Search Results - "Lam, Yun Wah"
-
1
A Concerted Enzymatic and Bioorthogonal Approach for Extra‐ and Intracellular Activation of Environment‐Sensitive Ruthenium(II)‐Based Imaging Probes and Photosensitizers
Published in Angewandte Chemie International Edition (17-07-2023)“…In this article, we report a novel targeting strategy involving the combination of an enzyme‐instructed self‐assembly (EISA) moiety and a strained cycloalkyne…”
Get full text
Journal Article -
2
Differential actions of chlorhexidine on the cell wall of Bacillus subtilis and Escherichia coli
Published in PloS one (11-05-2012)“…Chlorhexidine is a chlorinated phenolic disinfectant used commonly in mouthwash for its action against bacteria. However, a comparative study of the action of…”
Get full text
Journal Article -
3
Structure, Photophysical and Electrochemical Properties, Biomolecular Interactions, and Intracellular Uptake of Luminescent Cyclometalated Iridium(III) Dipyridoquinoxaline Complexes
Published in Inorganic chemistry (01-03-2010)“…A series of luminescent cyclometalated iridium(III) dipyridoquinoxaline complexes [Ir(N∧C)2(N∧N)](PF6) (HN∧C = 1-phenylpyrazole, Hppz, N∧N =…”
Get full text
Journal Article -
4
Luminescent Rhenium(I) Polypyridine Complexes Appended with an α-D-Glucose Moiety as Novel Biomolecular and Cellular Probes
Published in Chemistry : a European journal (18-07-2011)“…Glowing sweets! Three luminescent rhenium(I) polypyridine complexes have been modified with an α‐D‐glucose moiety. Their biomolecular binding, bacterial…”
Get full text
Journal Article -
5
A Triphenylphosphonium-Functionalised Cyclometalated Platinum(II) Complex as a Nucleolus-Specific Two-Photon Molecular Dye
Published in Chemistry : a European journal (06-04-2010)“…An organometallic cyclometalated platinum(II) complex, [Pt(L3)Cl][PF6], has been synthesised from a specially designed cyclometalating ligand, HL3…”
Get full text
Journal Article -
6
Synthesis and antitumor activity of a series of osmium(VI) nitrido complexes bearing quinolinolato ligands
Published in Chemical communications (Cambridge, England) (01-01-2013)“…A series of osmium(VI) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities…”
Get more information
Journal Article -
7
The molecularly imprinted polymer essentials: curation of anticancer, ophthalmic, and projected gene therapy drug delivery systems
Published in Journal of controlled release (10-10-2018)“…The development of polymeric materials as drug delivery systems has advanced from systems that rely on classical passive targeting to carriers that can sustain…”
Get full text
Journal Article -
8
Mitochondria-targeting cyclometalated iridium(III)–PEG complexes with tunable photodynamic activity
Published in Biomaterials (01-10-2013)“…Abstract We present a new class of phosphorescent cyclometalated iridium(III) polypyridine poly(ethylene glycol) (PEG) complexes [Ir(N^ C)2 (bpy–CONH–PEG)](PF6…”
Get full text
Journal Article -
9
TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration
Published in Nature communications (17-05-2021)“…Despite the widespread observations on the osteogenic effects of magnesium ion (Mg 2+ ), the diverse roles of Mg 2+ during bone healing have not been…”
Get full text
Journal Article -
10
Construction of an alkaline phosphatase-specific two-photon probe and its imaging application in living cells and tissues
Published in Biomaterials (01-09-2017)“…Alkaline phosphatase (ALP) is a family of enzymes involved in the regulation of important biological processes such as cell differentiation and bone…”
Get full text
Journal Article -
11
An iminocoumarin benzothiazole-based fluorescent probe for imaging hydrogen sulfide in living cells
Published in Talanta (Oxford) (01-04-2015)“…Hydrogen sulfide (H2S) has recently been identified as the third gaseous signaling molecule that is involved in regulating many important cellular processes…”
Get full text
Journal Article -
12
Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins
Published in Current biology (01-05-2007)“…The nucleolus is a subnuclear organelle in which rRNAs are transcribed, processed, and assembled with ribosomal proteins into ribosome subunits. Mass…”
Get full text
Journal Article -
13
Development of a Visible Light Triggerable Traceless Staudinger Ligation Reagent
Published in Journal of organic chemistry (02-11-2018)“…A series of substituted 9-methylenylanthracene photocages for diphenylphosphinothioesters have been synthesized to explore their photo-uncaging properties by…”
Get full text
Journal Article -
14
Design and Synthesis of Near-infrared Fluorescent Probes for Imaging of Biological Nitroxyl
Published in Scientific reports (20-11-2015)“…Nitroxyl (HNO), the reduced and protonated form of nitric oxide (NO), has recently been identified as an interesting and important signaling molecule in…”
Get full text
Journal Article -
15
Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes
Published in The Journal of cell biology (20-10-2008)“…The identification of interaction partners in protein complexes is a major goal in cell biology. Here we present a reliable affinity purification strategy to…”
Get full text
Journal Article -
16
A Quantitative Proteomics Analysis of Subcellular Proteome Localization and Changes Induced by DNA Damage
Published in Molecular & cellular proteomics (01-03-2010)“…A major challenge in cell biology is to identify the subcellular distribution of proteins within cells and to characterize how protein localization changes…”
Get full text
Journal Article -
17
A Unidirectional Cell Switching Gate by Engineering Grating Length and Bending Angle
Published in PloS one (28-01-2016)“…On a microgrooved substrate, cells migrate along the pattern, and at random positions, reverse their directions. Here, we demonstrate that these reversals can…”
Get full text
Journal Article -
18
Live Imaging of Planaria
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2018)“…Planarian regeneration involves a complex series of cellular events, precisely choreographed in space and time. Time-lapse imaging can provide powerful…”
Get more information
Journal Article -
19
Capturing instructive cues of tissue microenvironment by silica bioreplication
Published in Acta biomaterialia (15-01-2020)“…Cells in tissues are enveloped by an instructive niche made of the extracellular matrix. These instructive niches contain three general types of information:…”
Get full text
Journal Article -
20
Novel Blood Collection Method Allows Plasma Proteome Analysis from Single Zebrafish
Published in Journal of proteome research (05-04-2013)“…Zebrafish is an important model organism in biological research. One of the least explored tissues of zebrafish is blood, because the existing methods for…”
Get full text
Journal Article