Search Results - "Lam, Wai Har"
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Rhodium-BisbenzodioxanPhos Complex-Catalyzed Homogeneous Enantioselective Pauson-Khand-Type Cyclization in Alcoholic Solvents
Published in Advanced synthesis & catalysis (01-11-2005)“…The chiral atropisomeric diphosphane ligand (S)‐BisbenzodioxanPhos was found to be highly effective in the co‐operative processeses of aldehyde decarbonylation…”
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2
A New Class of Versatile Chiral-Bridged Atropisomeric Diphosphine Ligands: Remarkably Efficient Ligand Syntheses and Their Applications in Highly Enantioselective Hydrogenation Reactions
Published in Journal of the American Chemical Society (03-05-2006)“…A series of chiral diphosphine ligands denoted as PQ-Phos was prepared by atropdiastereoselective Ullmann coupling and ring-closure reactions. The Ullmann…”
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3
Effect of a Prodrug of the Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate on the Growth of Androgen-Independent Prostate Cancer In Vivo
Published in Nutrition and cancer (2008)“…Epigallocatechin-3-gallate (EGCG) is the major and most potent polyphenol compound of green tea that has been shown to have anticancer effects against various…”
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4
A pro-drug of the green tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) prevents differentiated SH-SY5Y cells from toxicity induced by 6-hydroxydopamine
Published in Neuroscience letters (29-01-2010)“…Regular consumption of green tea benefits people in prevention from cardiovascular disorders, obesity as well as neurodegenerative diseases…”
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A potential prodrug for a green tea polyphenol proteasome inhibitor: evaluation of the peracetate ester of (−)-epigallocatechin gallate [(−)-EGCG]
Published in Bioorganic & medicinal chemistry (01-11-2004)“…[Display omitted] Green tea has been shown to have many biological effects, including effects on metabolism, angiogenesis, oxidation, and cell proliferation…”
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6
Rhodium-Catalyzed Asymmetric Aqueous Pauson-Khand-Type Reaction
Published in Chemistry : a European journal (20-06-2005)“…An interesting rhodium‐catalyzed asymmetric aqueous Pauson–Khand‐type reaction was developed. A chiral atropisomeric dipyridyldiphosphane ligand was found to…”
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7
Semi-synthesis and proteasome inhibition of D-ring deoxy analogs of (-)-epigallocatechin gallate (EGCG), the active ingredient of green tea extract
Published in Canadian journal of chemistry (01-06-2008)“…A semi-synthetic route to the D -ring analogs of (-)-epigallocatechin gallate (EGCG) from the relatively abundant (-)-epigallocatechin (EGC), isolated from…”
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Tea polyphenols, their biological effects and potential molecular targets
Published in Histology and histopathology (01-04-2008)“…Tea is the most popular beverage in the world, second only to water. Tea contains an infusion of the leaves from the Camellia sinensis plant rich in…”
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Easily Accessible Benzamide-Derived P,O Ligands (Bphos) for Palladium-Catalyzed Carbon-Nitrogen Bond-Forming Reactions
Published in Chemistry, an Asian journal (05-02-2007)“…Easily accessible benzamide‐derived hemilabile phosphine ligands were efficiently prepared through ortho‐directed lithiation of the corresponding…”
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10
Iridium-catalyzed cascade decarbonylation/highly enantioselective Pauson–Khand-type cyclization reactions
Published in Tetrahedron: asymmetry (18-04-2006)“…An easily accessible chiral iridium-BINAP complex can effect the cooperative processes of decarbonylation of an aldehyde and cascaded enantioselective…”
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Green tea and tea polyphenols in cancer prevention
Published in Frontiers in bioscience (01-09-2004)“…The cancer-preventive effects of green tea and its main constituent (-)-epigallocatechin gallate [(-)-EGCG] are widely supported by results from…”
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12
Semi-synthesis and proteasome inhibition of D-ring deoxy analogs of
Published in Canadian journal of chemistry (01-06-2008)Get full text
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13
Investigation of the structure-activity relationship (SAR) of natural products ((-)-EGCG from green tea and YCK from Murraya paniculata)
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Dissertation -
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Investigation of the structure -activity relationship (SAR) of natural products ((−)-EGCG from green tea and YCK from Murraya paniculata)
Published 01-01-2004“…In view of the attention on the biological activity of (−)-epigallocatechin gallate (EGCG) from green tea and YCK from Murraya paniculata, this research aimed…”
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Dissertation -
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Synthetic peracetate tea polyphenols as potent proteasome inhibitors and apoptosis inducers in human cancer cells
Published in Frontiers in bioscience (01-05-2005)“…It has been suggested that proteasome activity is essential for tumor cell proliferation and drug resistance development. We have previously shown that natural…”
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