Search Results - "Lam, W. K. Jacky"

Convolutional neural network for discriminating nasopharyngeal carcinoma and benign hyperplasia on MRI by Wong, Lun M., King, Ann D., Ai, Qi Yong H., Lam, W. K. Jacky, Poon, Darren M. C., Ma, Brigette B. Y., Chan, K. C. Allen, Mo, Frankie K. F.

“…Objectives A convolutional neural network (CNN) was adapted to automatically detect early-stage nasopharyngeal carcinoma (NPC) and discriminate it from benign…”
Get full text

Recent advances in the management of nasopharyngeal carcinoma [version 1; peer review: 2 approved] by Lam, W. K. Jacky, Chan, Jason Y. K

“…Over the last few years, certain areas in the management nasopharyngeal carcinoma (NPC) that have an impact on the care of these patients have evolved,…”
Get full text

Intravoxel incoherent motion diffusion-weighted imaging for discrimination of benign and malignant retropharyngeal nodes by So, Tiffany Y., Ai, Qi-Yong H., Lam, W. K. Jacky, Qamar, Sahrish, Poon, Darren M. C., Hui, Edwin P., Mo, Frankie K. F., Chan, K. C. Allen, King, Ann D.

“…Purpose Anatomical imaging criteria for the diagnosis of malignant head and neck nodes may not always be reliable. This study aimed to evaluate the diagnostic…”
Get full text

A Novel Dirofilaria Species Causing Human and Canine Infections in Hong Kong by TO, Kelvin K. W, WONG, Samson S. Y, YUEN, Kwok-Yung, POON, Rosana W. S, TRENDELL-SMITH, Nigel J, NGAN, Antonio H. Y, LAM, Jacky W. K, TANG, Tommy H. C, AHCHONG, Ah-Kian, KAN, Joshua Chi-Hang, CHAN, Kwok-Hung

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Single-Molecule Sequencing Enables Long Cell-Free DNA Detection and Direct Methylation Analysis for Cancer Patients by Choy, L Y Lois, Peng, Wenlei, Jiang, Peiyong, Cheng, Suk Hang, Yu, Stephanie C Y, Shang, Huimin, Olivia Tse, O Y, Wong, John, Wong, Vincent Wai Sun, Wong, Grace L H, Lam, W K Jacky, Chan, Stephen L, Chiu, Rossa W K, Chan, K C Allen, Lo, Y M Dennis

“…Abstract Background Analysis of circulating tumor DNA has become increasingly important as a tool for cancer care. However, the focus of previous studies has…”
Get full text

High-resolution analysis for urinary DNA jagged ends by Xie, Tingting, Wang, Guangya, Ding, Spencer C., Lee, Wing-Shan, Cheng, Suk Hang, Chan, Rebecca W. Y., Zhou, Ze, Ma, Mary-Jane L., Han, Diana S. C., Teoh, Jeremy Y. C., Lam, W. K. Jacky, Jiang, Peiyong, Chiu, Rossa W. K., Chan, K. C. Allen, Lo, Y. M. Dennis

“…Single-stranded ends of double-stranded DNA (jagged ends) are more abundant in urinary DNA than in plasma DNA. However, the lengths of jagged ends in urinary…”
Get full text

Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma by Lam, W. K. Jacky, Jiang, Peiyong, Chan, K. C. Allen, Cheng, Suk H., Zhang, Haiqiang, Peng, Wenlei, Tse, O. Y. Olivia, Tong, Yu K., Gai, Wanxia, Zee, Benny C. Y., Ma, Brigette B. Y., Hui, Edwin P., Chan, Anthony T. C., Woo, John K. S., Chiu, Rossa W. K., Lo, Y. M. Dennis

“…Circulating tumor-derived DNA testing for cancer screening has recently been demonstrated in a prospective study on identification of nasopharyngeal carcinoma…”
Get full text

Towards multi-cancer screening using liquid biopsies by Lo, Y. M. Dennis, Lam, W. K. Jacky

“…Cell-free DNA and proteins are secreted into the bloodstream by multiple types of cancer. In a recently published prospective study involving 10,006 women,…”
Get full text

Circular RNAs as Urinary Biomarkers by Jacky Lam, W K, Dennis Lo, Y M

“…[...]as mentioned above, some circRNAs are abundant in the various human cell types (3). [...]the circRNA expression patterns are diverse among different cell…”
Get full text

Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases by Lam, W. K. Jacky, Jiang, Peiyong, Chan, K. C. Allen, Peng, Wenlei, Shang, Huimin, Heung, Macy M. S., Cheng, Suk Hang, Zhang, Haiqiang, Tse, O. Y. Olivia, Raghupathy, Radha, Ma, Brigette B. Y., Hui, Edwin P., Chan, Anthony T. C., Woo, John K. S., Chiu, Rossa W. K., Lo, Y. M. Dennis

“…Epstein-Barr virus (EBV) is associated with a number of diseases, including malignancies. Currently, it is not known whether patients with different…”
Get full text

Jagged Ends of Urinary Cell-Free DNA: Characterization and Feasibility Assessment in Bladder Cancer Detection by Zhou, Ze, Cheng, Suk Hang, Ding, Spencer C, Heung, Macy M S, Xie, Tingting, Cheng, Timothy H T, Lam, W K Jacky, Peng, Wenlei, Teoh, Jeremy Y C, Chiu, Peter K F, Ng, Chi-Fai, Jiang, Peiyong, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis

“…Abstract Background Double-stranded DNA in plasma is known to carry single-stranded ends, called jagged ends. Plasma DNA jagged ends are biomarkers for…”
Get full text

Early detection of nasopharyngeal carcinoma: performance of a short contrast-free screening magnetic resonance imaging by King, Ann D, Ai, Qi Yong H, Lam, W K Jacky, Tse, Irene O L, So, Tiffany Y, Wong, Lun M, Tsang, Jayden Yip Man, Leung, Ho Sang, Zee, Benny C Y, Hui, Edwin P, Ma, Brigette B Y, Vlantis, Alexander C, van Hasselt, Andrew C, Chan, Anthony T C, Woo, John K S, Chan, K C Allen

“…Although contrast-enhanced magnetic resonance imaging (MRI) detects early-stage nasopharyngeal carcinoma (NPC) not detected by endoscopic-guided biopsy (EGB),…”
Get full text

Dynamic Changes of Post-Radiotherapy Plasma Epstein-Barr Virus DNA in a Randomized Trial of Adjuvant Chemotherapy Versus Observation in Nasopharyngeal Cancer by Hui, Edwin Pun, Ma, Brigette B Y, Lam, W K Jacky, Chan, K C Allen, Mo, Frankie, Ai, Qi-Yong Hemis, King, Ann D, Wong, Chi Hang, Wong, Kenneth C W, Lam, Daisy C M, Tong, Macy, Poon, Darren M C, Li, Leung, Lau, Thomas K H, Wong, Kwan Hung, Lo, Y M Dennis, Chan, Anthony T C

“…To study the dynamic changes in plasma Epstein-Barr virus (pEBV) DNA after radiotherapy in nasopharyngeal cancer (NPC). We conducted a randomized controlled…”
Get full text

DNA of Erythroid Origin Is Present in Human Plasma and Informs the Types of Anemia by Lam, W K Jacky, Gai, Wanxia, Sun, Kun, Wong, Raymond S M, Chan, Rebecca W Y, Jiang, Peiyong, Chan, Natalie P H, Hui, Winnie W I, Chan, Anthony W H, Szeto, Cheuk-Chun, Ng, Siew C, Law, Man-Fai, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis

“…There is much interest in the tissue of origin of circulating DNA in plasma. Data generated using DNA methylation markers have suggested that hematopoietic…”
Get full text

Fragment Ends of Circulating Microbial DNA as Signatures for Pathogen Detection in Sepsis by Wang, Guangya, Lam, W K Jacky, Ling, Lowell, Ma, Mary-Jane L, Ramakrishnan, Saravanan, Chan, Don C T, Lee, Wing-Shan, Cheng, Suk Hang, Chan, Rebecca W Y, Yu, Stephanie C Y, Tse, Irene O L, Wong, Wai Tat, Jiang, Peiyong, Chiu, Rossa W K, Allen Chan, K C, Lo, Y M Dennis

“…Nuclear-derived cell-free DNA (cfDNA) molecules in blood plasma are nonrandomly fragmented, bearing a wealth of information related to tissues of origin…”
Get full text

Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma by Che, Huiwen, Jiang, Peiyong, Choy, L Y Lois, Cheng, Suk Hang, Peng, Wenlei, Chan, Rebecca W Y, Liu, Jing, Zhou, Qing, Lam, W K Jacky, Yu, Stephanie C Y, Lau, So Ling, Leung, Tak Y, Wong, John, Wong, Vincent Wai-Sun, Wong, Grace L H, Chan, Stephen L, Chan, K C Allen, Lo, Y M Dennis

“…Recent studies have revealed an unexplored population of long cell-free DNA (cfDNA) molecules in human plasma using long-read sequencing technologies. However,…”
Get full text

Clinical applications of circulating tumor-derived DNA in the management of gastrointestinal cancers - current evidence and future directions by Lam, Rachel C T, Johnson, David, Lam, Gigi, Li, Michelle L Y, Wong, Joyce W L, Lam, W K Jacky, Chan, K C Allen, Ma, Brigette

“…Advances in Next Generation Sequencing (NGS) technologies have enabled the accurate detection and quantification of circulating tumor-derived (ct)DNA in most…”
Get full text

Differential detection of megakaryocytic and erythroid DNA in plasma in hematological disorders by Lam, W. K. Jacky, Gai, Wanxia, Bai, Jinyue, Tam, Tommy H. C., Cheung, Wai Fung, Ji, Lu, Tse, Irene O. L., Tsang, Amy F. C., Li, Maggie Z. J., Jiang, Peiyong, Law, Man Fai, Wong, Raymond S. M., Chan, K. C. Allen, Lo, Y. M. Dennis

“…The tissues of origin of plasma DNA can be revealed by methylation patterns. However, the relative DNA contributions from megakaryocytes and erythroblasts into…”
Get full text

Personalized treatment for hepatocellular carcinoma: Current status and future perspectives by Chan, Stephen L, Wong, Nathalie, Lam, W K Jacky, Kuang, Ming

“…Systemic treatment for hepatocellular carcinoma (HCC) has been advancing rapidly over the last decade. More novel agents, including both targeted agents and…”
Get full text

Nasopharyngeal cancer screening with an anti-BNLF2b antibody: a new arrow in the quiver? by Lam, W. K. Jacky, Chan, Anthony T. C.

“…Epstein–Barr virus (EBV)-based biomarkers are used for nasopharyngeal carcinoma (NPC) screening in endemic regions. A recent prospective study describes the…”
Get full text