Search Results - "Lam, Stephen T."
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A directional switch of integrin signalling and a new anti-thrombotic strategy
Published in Nature (London) (07-11-2013)“…The direction of integrin signalling is found to be determined by the coordinated and opposing binding waves of talin and Gα 13 to the same region of the…”
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The P2Y12 Antagonists, 2-Methylthioadenosine 5′-Monophosphate Triethylammonium Salt and Cangrelor (ARC69931MX), Can Inhibit Human Platelet Aggregation through a Gi-independent Increase in cAMP Levels
Published in The Journal of biological chemistry (12-06-2009)“…ADP plays an integral role in the process of hemostasis by signaling through two platelet G-protein-coupled receptors, P2Y1 and P2Y12. The recent use of…”
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Phenotypic features of carbohydrate sulfotransferase 3 (CHST3) deficiency in 24 patients: Congenital dislocations and vertebral changes as principal diagnostic features
Published in American journal of medical genetics. Part A (01-10-2010)“…We recently reported on the deficiency of carbohydrate sulfotransferase 3 (CHST3; chondroitin‐6‐sulfotransferase) in six subjects diagnosed with recessive…”
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Modeling LiF and FLiBe Molten Salts with Robust Neural Network Interatomic Potential
Published in ACS applied materials & interfaces (02-06-2021)“…Lithium-based molten salts have attracted significant attention due to their applications in energy storage, advanced fission reactors, and fusion devices…”
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The Angiogenic Factor Cysteine-Rich 61 (CYR61, CCN1) Supports Vascular Smooth Muscle Cell Adhesion and Stimulates Chemotaxis through Integrin α6β1 and Cell Surface Heparan Sulfate Proteoglycans
Published in Endocrinology (Philadelphia) (01-04-2002)“…Cysteine-rich 61 (CYR61, CCN1) is a heparin-binding, extracellular, matrix-associated protein of the cysteine-rich 61/nephroblastoma family, which also…”
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Redox potential control in molten salt systems for corrosion mitigation
Published in Corrosion science (01-11-2018)“…In a molten salt nuclear reactor system, the redox potential must be controlled for mitigating corrosion of structural materials. The paper presented a…”
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Large-scale gene discovery in the oomycete Phytophthora infestans reveals likely components of phytopathogenicity shared with true fungi
Published in Molecular plant-microbe interactions (01-03-2005)“…To overview the gene content of the important pathogen Phytophthora infestans, large-scale cDNA and genomic sequencing was performed. A set of 75,757…”
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Modeling and predicting total hydrogen adsorption in nanoporous carbon materials for advanced nuclear systems
Published in Journal of nuclear materials (01-12-2018)“…The retention of hydrogen in a variety of disordered carbon materials including graphene nanoplatelets and amorphous carbon was measured by volumetric…”
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Deep neural network based quantum simulations and quasichemical theory for accurate modeling of molten salt thermodynamics
Published in Chemical science (Cambridge) (20-07-2022)“…With dual goals of efficient and accurate modeling of solvation thermodynamics in molten salt liquids, we employ ab initio molecular dynamics (AIMD)…”
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Transferable Deep Learning Potential Reveals Intermediate-Range Ordering Effects in LiF–NaF–ZrF4 Molten Salt
Published in JACS Au (26-12-2022)“…LiF–NaF–ZrF4 multicomponent molten salts are promising candidate coolants for advanced clean energy systems owing to their desirable thermophysical and…”
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Weak and strong hydrogen interactions on porous carbon materials in high-temperature systems
Published in Journal of nuclear materials (01-06-2019)“…The adsorption mechanisms of hydrogen on porous carbon materials were examined using constant volume chemisorption at 700 °C, the operating temperature of…”
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Treatment with trimetazidine dihydrochloride and lung cancer survival: Implications on metabolic re-programming
Published in Lung cancer (Amsterdam, Netherlands) (01-11-2024)“…•Trimetazidine use was associated with lower all-cause mortality, particularly non-cardiovascular mortality in ischemic heart patients with lung cancers.•This…”
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Short- to Intermediate-Range Structure, Transport, and Thermophysical Properties of LiF–NaF–ZrF4 Molten Salts
Published in Frontiers in physics (07-03-2022)“…LiF–NaF–ZrF 4 multicomponent molten salts are identified as promising candidates for coolant salts in molten salt reactors and advanced high-temperature…”
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Transferable Deep Learning Potential Reveals Intermediate-Range Ordering Effects in LiF-NaF-ZrF 4 Molten Salt
Published in JACS Au (26-12-2022)“…LiF-NaF-ZrF multicomponent molten salts are promising candidate coolants for advanced clean energy systems owing to their desirable thermophysical and…”
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Urinary incontinence should be added to the manifestation in women with Marfan syndrome
Published in International Urogynecology Journal (01-05-2010)“…Introduction and hypothesis We aimed to compare the incidence of urinary incontinence in women with Marfan syndrome and controls, hypothesizing that connective…”
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2,5-Dialkylresorcinol Biosynthesis in Pseudomonas aurantiaca: Novel Head-to-Head Condensation of Two Fatty Acid-Derived Precursors
Published in Journal of Bacteriology (01-02-2003)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A fast neural network approach for direct covariant forces prediction in complex multi-element extended systems
Published in Nature machine intelligence (01-10-2019)“…Neural network force field (NNFF) is a method for performing regression on atomic structure–force relationships, bypassing the expensive quantum mechanics…”
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Prenatal phenotype of Kabuki syndrome: A case series and literature review
Published in Prenatal diagnosis (01-08-2021)“…Objectives Kabuki syndrome (KS) is a genetic disorder characterized by intellectual disability, facial dysmorphism and congenital anomalies. We aim to…”
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Clinical and molecular characterization study of Chinese Kabuki syndrome in Hong Kong
Published in American journal of medical genetics. Part A (01-03-2021)“…Kabuki syndrome (OMIM #147920 and 300867) is a rare genetic disorder characterized by a distinctive facial gestalt, intellectual disability and multiple…”
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