Search Results - "Lam, Siu W."

Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia by Pillay, Janesh, Ramakers, Bart P., Kamp, Vera M., Loi, Adele Lo Tam, Lam, Siu W., Hietbrink, Falco, Leenen, Luke P., Tool, Anton T., Pickkers, Peter, Koenderman, Leo

“…Systemic inflammation results in release of refractory neutrophils which can cause susceptibility to infections and activates differentiated neutrophils, which…”
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The cancer secretome, current status and opportunities in the lung, breast and colorectal cancer context by Schaaij-Visser, Tieneke B.M., de Wit, Meike, Lam, Siu W., Jiménez, Connie R.

“…Despite major improvements on the knowledge and clinical management, cancer is still a deadly disease. Novel biomarkers for better cancer detection, diagnosis…”
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Infection of Previously Closed Urachus Mimicking Malignancy: A Case Report and Literature Review of Radiological Findings to the Diagnosis by Lam, Siu W, Linsen, Philip VM, Elgersma, Otto E

“…The urachus is a vestigial structure of the allantois and cloaca. It involutes as fetal development progresses to become a fibrous cord, which courses between…”
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Genotypes of CYP2C8 and FGD4 and their association with peripheral neuropathy or early dose reduction in paclitaxel-treated breast cancer patients by Lam, Siu W, Frederiks, Charlotte N, van der Straaten, Tahar, Honkoop, Aafke H, Guchelaar, Henk-Jan, Boven, Epie

“…Background: The purpose of this study was to evaluate single-nucleotide polymorphisms (SNPs) in genes encoding key metabolising enzymes or involved in…”
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Single-nucleotide polymorphisms in the genes of CES2, CDA and enzymatic activity of CDA for prediction of the efficacy of capecitabine-containing chemotherapy in patients with metastatic breast cancer by Lam, Siu W., van der Noort, Vincent, van der Straaten, Tahar, Honkoop, Aafke H., Peters, Godefridus J., Guchelaar, Henk-Jan, Boven, Epie

“…[Display omitted] We examined whether genetic polymorphisms (SNPs) in the capecitabine activation pathway and CDA enzymatic activity were associated with…”
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Angiogenesis- and Hypoxia-Associated Proteins as Early Indicators of the Outcome in Patients with Metastatic Breast Cancer Given First-Line Bevacizumab-Based Therapy by Lam, Siu W, Nota, Nienke M, Jager, Agnes, Bos, Monique M E M, van den Bosch, Joan, van der Velden, Ankie M T, Portielje, Johanneke E A, Honkoop, Aafke H, van Tinteren, Harm, Boven, Epie

“…We examined whether pretreatment levels of angiogenesis- or hypoxia-related proteins and their changes after one cycle of first-line bevacizumab-based therapy…”
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Imaging in interventional oncology, the better you see, the better you treat by Gómez, Fernando M, Van der Reijd, Denise J, Panfilov, Ilia A, Baetens, Tarik, Wiese, Kevin, Haverkamp‐Begemann, Naomi, Lam, Siu W, Runge, Jurgen H, Rice, Samuel L, Klompenhouwer, Elisabeth G, Maas, Monique, Helmberger, Thomas, Beets‐Tan, Regina GH

“…Summary Imaging and image processing is the fundamental pillar of interventional oncology in which diagnostic, procedure planning, treatment and follow‐up are…”
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A functional bioassay to determine the activity of anti-VEGF antibody therapy in blood of patients with cancer by Wentink, Madelon Q, Broxterman, Henk J, Lam, Siu W, Boven, Epie, Walraven, Maudy, Griffioen, Arjan W, Pili, Roberto, van der Vliet, Hans J, de Gruijl, Tanja D, Verheul, Henk M W

“…Background: Only a small proportion of patients respond to anti-VEGF therapy, pressing the need for a reliable biomarker that can identify patients who will…”
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First in humans: dobutamine stress cardiac computed tomography to evaluate dynamic compression of an anomalous left coronary artery by Linsen, Philip V.M, Kofflard, Marcel J.M, Lam, Siu W, Kock, Marc C.J.M

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Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer by Warmoes, Marc, Lam, Siu W, van der Groep, Petra, Jaspers, Janneke E, Smolders, Yvonne H C M, de Boer, Leon, Pham, Thang V, Piersma, Sander R, Rottenberg, Sven, Boven, Epie, Jonkers, Jos, van Diest, Paul J, Jimenez, Connie R

“…Breast cancer arising in female BRCA1 mutation carriers is characterized by an aggressive phenotype and early age of onset. We performed tandem mass…”
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Evaluation of hematological parameters on admission for the prediction of 7-day in-hospital mortality in a large trauma cohort by Lam, Siu W, Leenen, Luke P H, van Solinge, Wouter W, Hietbrink, Falco, Huisman, Albert

“…We evaluated the complete blood count (CBC) for the prediction of 7-day in-hospital mortality in a large adult trauma cohort. We conducted an analysis of two…”
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Comparison between the prognostic value of the white blood cell differential count and morphological parameters of neutrophils and lymphocytes in severely injured patients for 7-day in-hospital mortality by Lam, Siu W., Leenen, Luke P. H., van Solinge, Wouter W., Hietbrink, Falco, Huisman, Albert

“…Context: Current laboratory parameters provide limited information about the prognosis of severely injured patients; therefore, novel laboratory parameters are…”
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Abstract P6-08-09: Genetic polymorphisms (SNPs) as predictive markers for paclitaxel-induced peripheral neuropathy (PNP) and capecitabine-induced hand-foot syndrome (HFS) in HER-2 negative metastatic breast cancer patients by Lam, Siu W, Frederiks, Charlotte N, van der Straaten, Tahar, de Groot, Steffen M, Jager, Agnes, Bos, Monique MEM, Linn, Sabine C, van den Bosch, Joan, Braun, Hans J, van der Velden, Ankie MT, Los, Maartje, Portielje, Jojanneke EA, Kroep, Judith R, Honkoop, Aafke H, Smorenburg, Carolien H, Tanis, Bea, van Riel, Johanna MGH, Meerum Terwogt, Jetske M, den Boer, Marien O, Douma, Joep, Jeurissen, Frank, Berends, Johan, Guchelaar, Henk-Jan, Boven, Epie

“…Abstract Background Newly identified SNPs in genes encoding metabolizing enzymes (CYP2C8, CYP3A4) and drug target (TUBB2A) of paclitaxel have been associated…”
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Abstract P3-06-09: Plasma biomarker analysis in patients with HER2-negative locally recurrent or metastatic breast cancer (LR/MBC) treated with first-line bevacizumab (A) and paclitaxel (T) without or with capecitabine (X) by Lam, Siu W, Nota, Nienke M, de Groot, Steffen M, Jager, Agnes, Bos, Monique MEM, Linn, Sabine C, van den Bosch, Joan, Braun, Hans J, van der Velden, Ankie MT, Los, Maartje, Portielje, Johanneke EA, Kroep, Judith R, Honkoop, Aafke H, Smorenburg, Carolien H, Tanis, Bea, van Riel, Johanna MGH, Meerum Terwogt, Jetske M, den Boer, Marien O, Douma, Joep, Jeurissen, Frank, Berends, Johan, van Tinteren, Harm, Boven, Epie

“…Abstract Background The phase II ATX trial aimed at evaluating safety and efficacy of first-line AT or ATX for HER2-negative LR/MBC (NTR1348; BOOG 2006-06)…”
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Plasma VEGF-a, angiopoietin-2 (ANG2) and soluble(s)TIE2 in patients (pts) with HER2-negative locally recurrent or metastatic breast cancer (LR/MBC) treated with first-line bevacizumab (A) and paclitaxel (T) without or with capecitabine (X) by Lam, Siu W., de Groot, Steffen M., Honkoop, Aafke H., Nota, Nienke M., Jager, A., van der Velden, Ankie M.T., Bos, Monique M.E.M., Linn, Sabine C., Van Den Bosch, J., Kroep, Judith R., Braun, J. J., de Haas, Richard R., Smorenburg, Carolien H., de Graaf, Hiltje, Portielje, Johanna Elisabeth A., Los, Maartje, de Gooyer, Domingo, van Tinteren, Harm, Boven, Epie

“…Abstract only 1072 Background: In the randomized phase II ATX trial, pts with HER2-negative LR/MBC were treated with first-line AT or ATX. We determined the…”
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Infection of Previously Closed Urachus Mimicking Malignancy: A Case Report and Literature Review of Radiological Findings to the Diagnosis by Lam, Siu W, Linsen, Philip Vm, Elgersma, Otto E

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