Search Results - "Lam, Simon W"

Predictors of response to fixed-dose vasopressin in adult patients with septic shock by Sacha, Gretchen L., Lam, Simon W., Duggal, Abhijit, Torbic, Heather, Bass, Stephanie N., Welch, Sarah C., Butler, Robert S., Bauer, Seth R.

“…Background Vasopressin is often utilized for hemodynamic support in patients with septic shock. However, the most appropriate patient to initiate therapy in is…”
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Effects of Norepinephrine and Vasopressin Discontinuation Order in the Recovery Phase of Septic Shock: A Systematic Review and Individual Patient Data Meta‐Analysis by Hammond, Drayton A., Sacha, Gretchen L., Bissell, Brittany D., Musallam, Nadine, Altshuler, Diana, Flannery, Alexander H., Lam, Simon W., Bauer, Seth R.

“…Objective The impact of vasopressin and norepinephrine discontinuation order in the recovery phase of septic shock remains controversial. This systematic…”
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Characterizing Critical Care Pharmacy Services Across the United States by MacLaren, Robert, Roberts, Russel J, Dzierba, Amy L, Buckley, Mitchell, Lat, Ishaq, Lam, Simon W

“…Involvement of clinical pharmacists in the ICU attenuates costs, avoids adverse drug events, and reduces morbidity and mortality. This survey assessed services…”
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Ketamine Safety and Use in the Emergency Department for Pain and Agitation/Delirium: A Health System Experience by Mo, Hanjie, Campbell, Matthew J, Fertel, Baruch S, Lam, Simon W, Wells, Elizabeth J, Casserly, Elizabeth, Meldon, Stephen W

“…Two protocols were developed to guide the use of subdissociative dose ketamine (SDDK) for analgesia and dissociative sedation ketamine for severe…”
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Association of Arterial pH With Hemodynamic Response to Vasopressin in Patients With Septic Shock: An Observational Cohort Study by Bauer, Seth R, Sacha, Gretchen L, Siuba, Matthew T, Lam, Simon W, Reddy, Anita J, Duggal, Abhijit, Vachharajani, Vidula

“…Vasopressin is reported to retain vasoconstrictive activity in the setting of acidemia, but preclinical models are inconsistent and studies have not evaluated…”
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Systematic Review and Meta-Analysis of Procalcitonin-Guidance Versus Usual Care for Antimicrobial Management in Critically Ill Patients: Focus on Subgroups Based on Antibiotic Initiation, Cessation, or Mixed Strategies by Lam, Simon W., Bauer, Seth R., Fowler, Robert, Duggal, Abhijit

“…OBJECTIVE:Numerous studies have evaluated the use of procalcitonin guidance during different phases of antibiotics management (initiation, cessation, or a…”
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Association of Catecholamine Dose, Lactate, and Shock Duration at Vasopressin Initiation With Mortality in Patients With Septic Shock by Sacha, Gretchen L., Lam, Simon W., Wang, Lu, Duggal, Abhijit, Reddy, Anita J., Bauer, Seth R.

“…To determine the association of catecholamine dose, lactate concentration, and timing from shock onset at vasopressin initiation with in-hospital mortality…”
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The PS1 hairpin of Mcm3 is essential for viability and for DNA unwinding in vitro by Lam, Simon K W, Ma, Xiaoli, Sing, Tina L, Shilton, Brian H, Brandl, Christopher J, Davey, Megan J

“…The pre-sensor 1 (PS1) hairpin is found in ring-shaped helicases of the AAA+ family (ATPases associated with a variety of cellular activities) of proteins and…”
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Clinical and Microbiological Outcomes in Obese Patients Receiving Colistin for Carbapenem-Resistant Gram-Negative Bloodstream Infection by Lam, Simon W, Athans, Vasilios

“…Carbapenem-resistant infections are associated with poor outcomes, and treatment options are limited. Colistin is one of few antibiotics which retain activity…”
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Healthcare system conversion to a biosimilar: Trials and tribulations by Lam, Simon W, Amoline, Kevin, Marcum, Christopher, Leonard, Mandy

“…Abstract Purpose While biologic medications have transformed the care and management of millions of patients, they are a large financial strain on the…”
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Phenobarbital and symptom-triggered lorazepam versus lorazepam alone for severe alcohol withdrawal in the intensive care unit by Nguyen, Thu A., Lam, Simon W.

“…A symptom-triggered lorazepam regimen is the standard for treating alcohol withdrawal syndrome (AWS) in an inpatient setting. However, in severe AWS, lorazepam…”
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Balanced Crystalloids Versus Saline in Critically Ill Adults: A Systematic Review and Meta-analysis by Hammond, Drayton A., Lam, Simon W., Rech, Megan A., Smith, Melanie N., Westrick, Jennifer, Trivedi, Abhaya P., Balk, Robert A.

“…Background: The optimal resuscitative fluid remains controversial. Objective: To assess the association between crystalloid fluid and outcomes in critically…”
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Amikacin Pharmacokinetics During Continuous Veno-Venous Hemodialysis by Lam, Simon W., Bauer, Seth R.

“…Introduction Little is known about the pharmacokinetics of amikacin during continuous renal replacement therapy. Methods This prospective observational study…”
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Association Between Colistin Dose and Microbiologic Outcomes in Patients With Multidrug-Resistant Gram-Negative Bacteremia by Vicari, Giulia, Bauer, Seth R., Neuner, Elizabeth A., Lam, Simon W.

“…Background. Colistin is increasingly used for the treatment of multidrug-resistant gram-negative infections. However, colistin dosing varies greatly and the…”
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Inhaled Epoprostenol Through Noninvasive Routes of Ventilator Support Systems by Ammar, Mahmoud A., Sasidhar, Madhu, Lam, Simon W.

“…Background: The administration of inhaled epoprostenol (iEPO) through noninvasive routes of ventilator support systems has never been previously evaluated…”
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Effect of Pharmacy-Driven Bedside Discharge Medication Delivery Program on Day 30 Hospital Readmission by Lam, Simon W., Sokn, Erick

“…Background: Previous studies demonstrated that transitions of care bundles, which include bedside discharge medication delivery (BDMD), may be helpful in…”
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Effect of clinical pharmacist interventions on cost in an integrated health system specialty pharmacy by Lankford, Cory, Dura, Jillian, Tran, Annie, Lam, Simon W, Naelitz, Bryan, Willner, Marc, Geyer, Kristel

“…Patients who are prescribed specialty medications require close monitoring, including assessment of laboratory parameters, toxicities, and adherence. Specialty…”
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Author's Response: Abrupt Discontinuation Versus Down-Titration of Vasopressin in Patients Recovering from Septic Shock by Lam, Simon W., Sacha, Gretchen L., Bauer, Seth R.

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Abrupt Discontinuation Versus Down-Titration of Vasopressin in Patients Recovering from Septic Shock by Lam, Simon W., Sacha, Gretchen L., Duggal, Abhijit, Reddy, Anita J., Bauer, Seth R.

“…To compare patient outcomes based on management of arginine vasopressin (AVP) during the recovery phase of septic shock (abrupt vs. tapering discontinuation)…”
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Cost-effectiveness of three different strategies for the treatment of first recurrent Clostridium difficile infection diagnosed in a community setting by Lam, Simon W, Neuner, Elizabeth A, Fraser, Thomas G, Delgado, David, Chalfin, Donald B

“…A significant portion of patients with Clostridium difficile infections (CDI) experience recurrence, and there is little consensus on its treatment. With the…”
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