Search Results - "Lam, Sherry"

Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability by Bonaventura, Jordi, Lam, Sherry, Carlton, Meghan, Boehm, Matthew A., Gomez, Juan L., Solís, Oscar, Sánchez-Soto, Marta, Morris, Patrick J., Fredriksson, Ida, Thomas, Craig J., Sibley, David R., Shaham, Yavin, Zarate, Carlos A., Michaelides, Michael

“…Ketamine, a racemic mixture of (S)-ketamine and (R)-ketamine enantiomers, has been used as an anesthetic, analgesic and more recently, as an antidepressant…”
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High-potency ligands for DREADD imaging and activation in rodents and monkeys by Bonaventura, Jordi, Eldridge, Mark A. G., Hu, Feng, Gomez, Juan L., Sanchez-Soto, Marta, Abramyan, Ara M., Lam, Sherry, Boehm, Matthew A., Ruiz, Christina, Farrell, Mitchell R., Moreno, Andrea, Galal Faress, Islam Mustafa, Andersen, Niels, Lin, John Y., Moaddel, Ruin, Morris, Patrick J., Shi, Lei, Sibley, David R., Mahler, Stephen V., Nabavi, Sadegh, Pomper, Martin G., Bonci, Antonello, Horti, Andrew G., Richmond, Barry J., Michaelides, Michael

“…Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a popular chemogenetic technology for manipulation of neuronal activity in…”
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Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search by Bonaventura, Jordi, Gomez, Juan L., Carlton, Meghan L., Lam, Sherry, Sanchez-Soto, Marta, Morris, Patrick J., Moaddel, Ruin, Kang, Hye Jin, Zanos, Panos, Gould, Todd D., Thomas, Craig J., Sibley, David R., Zarate, Carlos A., Michaelides, Michael

“…The off-label use of racemic ketamine and the FDA approval of (S)-ketamine are promising developments for the treatment of depression. Nevertheless, racemic…”
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A non-canonical striatopallidal Go pathway that supports motor control by Labouesse, Marie A., Torres-Herraez, Arturo, Chohan, Muhammad O., Villarin, Joseph M., Greenwald, Julia, Sun, Xiaoxiao, Zahran, Mysarah, Tang, Alice, Lam, Sherry, Veenstra-VanderWeele, Jeremy, Lacefield, Clay O., Bonaventura, Jordi, Michaelides, Michael, Chan, C. Savio, Yizhar, Ofer, Kellendonk, Christoph

“…In the classical model of the basal ganglia, direct pathway striatal projection neurons (dSPNs) send projections to the substantia nigra (SNr) and…”
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Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior by Gomez, Juan L., Bonaventura, Jordi, Keighron, Jacqueline, Wright, Kelsey M., Marable, Dondre L., Rodriguez, Lionel A., Lam, Sherry, Carlton, Meghan L., Ellis, Randall J., Jordan, Chloe J., Bi, Guo-hua, Solis, Oscar, Pignatelli, Marco, Bannon, Michael J., Xi, Zheng-Xiong, Tanda, Gianluigi, Michaelides, Michael

“…Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn 2+ ) also binds to the DAT, but the in vivo…”
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Curcumin effects on blood lipid profile in a 6-month human study by Baum, Larry, Cheung, Stanley K.K., Mok, Vincent C.T., Lam, Linda C.W., Leung, Vivian P.Y., Hui, Elsie, Ng, Chelsia C.Y., Chow, Moses, Ho, Ping C., Lam, Sherry, Woo, Jean, Chiu, Helen F.K., Goggins, William, Zee, Benny, Wong, Adrian, Mok, Hazel, Cheng, William K.F., Fong, Carmen, Lee, Jenny S.W., Chan, Ming-Houng, Szeto, Samuel S.L., Lui, Victor W.C., Tsoh, Joshua, Kwok, Timothy C.Y., Chan, Iris H.S., Lam, Christopher W.K.

“…Studies in animals and a short-term human study have suggested that curcumin, a polyphenolic compound concentrated in the curry spice turmeric, decreases serum…”
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Rapid determination of five probe drugs and their metabolites in human plasma and urine by liquid chromatography/tandem mass spectrometry: application to cytochrome P450 phenotyping studies by Yin, Ophelia Q. P., Lam, Sherry S. L., Lo, Cindy M. Y., Chow, Moses S. S.

“…A liquid chromatography/mass spectrometry method, for rapid determination of five cytochrome P450 (CYP) probe drugs and their relevant metabolites in human…”
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Simultaneous determination of paracetamol and dextropropoxyphene in human plasma by liquid chromatography/tandem mass spectrometry: application to clinical bioequivalence studies by Yin, Ophelia Q. P., Lam, Sherry S. L., Chow, Moses S. S.

“…A liquid chromatography/mass spectrometry method for simultaneous determination of paracetamol and dextropropoxyphene in human plasma is described. Paracetamol…”
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Essential role of P-glycoprotein in the mechanism of action of oliceridine by Ventriglia, Emilya, Rizzo, Arianna, Gomez, Juan L, Friedman, Jacob, Lam, Sherry, Solís, Oscar, Rais, Rana, Bonaventura, Jordi, Michaelides, Michael

“…Mu opioid receptor (MOR) agonists comprise the most effective analgesics, but their therapeutic utility is limited by adverse effects. One approach for…”
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The show must go on. Reply to “Distinct functions of S-ketamine and R-ketamine in mediating biobehavioral processes of drug dependency: comments on Bonaventura et al” by Insop Shim by Bonaventura, Jordi, Lam, Sherry, Carlton, Meghan, Boehm, Matthew, Gomez, Juan L., Solís, Oscar, Sánchez-Soto, Marta, Morris, Patrick J., Fredriksson, Ida, Thomas, Craig J., Sibley, David R., Shaham, Yavin, Zarate, Carlos A., Michaelides, Michael

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Opioid-galanin receptor heteromers mediate the dopaminergic effects of opioids by Cai, Ning-Sheng, Quiroz, César, Bonaventura, Jordi, Bonifazi, Alessandro, Cole, Thomas O, Purks, Julia, Billing, Amy S, Massey, Ebonie, Wagner, Michael, Wish, Eric D, Guitart, Xavier, Rea, William, Lam, Sherry, Moreno, Estefanía, Casadó-Anguera, Verònica, Greenblatt, Aaron D, Jacobson, Arthur E, Rice, Kenner C, Casadó, Vicent, Newman, Amy H, Winkelman, John W, Michaelides, Michael, Weintraub, Eric, Volkow, Nora D, Belcher, Annabelle M, Ferré, Sergi

“…Identifying non-addictive opioid medications is a high priority in medical sciences, but μ-opioid receptors mediate both the analgesic and addictive effects of…”
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Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging by Bonaventura, Jordi, Boehm, Matthew A, Jedema, Hank P, Solis, Oscar, Pignatelli, Marco, Song, Xiaowei, Lu, Hanbing, Richie, Christopher T, Zhang, Shiliang, Gomez, Juan L, Lam, Sherry, Morales, Marisela, Gharbawie, Omar A, Pomper, Martin G, Stein, Elliot A, Bradberry, Charles W, Michaelides, Michael

“…Optogenetics is a widely used technology with potential for translational research. A critical component of such applications is the ability to track the…”
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Time will tell. Reply to “Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al.” by Chen et al by Bonaventura, Jordi, Lam, Sherry, Carlton, Meghan, Boehm, Matthew, Gomez, Juan L., Solís, Oscar, Sánchez-Soto, Marta, Morris, Patrick J., Fredriksson, Ida, Thomas, Craig J., Sibley, David R., Shaham, Yavin, Zarate, Carlos A., Michaelides, Michael

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18F-labeled radiotracers for in vivo imaging of DREADD with positron emission tomography by Hu, Feng, Morris, Patrick J., Bonaventura, Jordi, Fan, Hong, Mathews, William B., Holt, Daniel P., Lam, Sherry, Boehm, Matthew, Dannals, Robert F., Pomper, Martin G., Michaelides, Michael, Horti, Andrew G.

“…Designer Receptors Exclusively Activated by Designer Drugs (DREADD) are a preclinical chemogenetic approach with clinical potential for various disorders…”
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Elucidating the effects of typical and atypical dopamine uptake inhibitors on the phasic release of dopamine in mice by Keighron, Jacqueline D., Bonaventura, Jordi, Li, Yang, Sandtner, Walter, Slack, Rachel, Cao, Jian Jing, Lam, Sherry, Michaelides, Michael, Sitte, Harald, Newman, Amy H., Tanda, Gianluigi

“…Atypical dopamine uptake inhibitors (DUIs), such as JHW 007, bind to the dopamine transporter (DAT), the same pharmacological target shared by psychostimulants…”
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18 F-labeled radiotracers for in vivo imaging of DREADD with positron emission tomography by Hu, Feng, Morris, Patrick J, Bonaventura, Jordi, Fan, Hong, Mathews, William B, Holt, Daniel P, Lam, Sherry, Boehm, Matthew, Dannals, Robert F, Pomper, Martin G, Michaelides, Michael, Horti, Andrew G

“…Designer Receptors Exclusively Activated by Designer Drugs (DREADD) are a preclinical chemogenetic approach with clinical potential for various disorders…”
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Synaptic Zn 2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior by Gomez, Juan L, Bonaventura, Jordi, Keighron, Jacqueline, Wright, Kelsey M, Marable, Dondre L, Rodriguez, Lionel A, Lam, Sherry, Carlton, Meghan L, Ellis, Randall J, Jordan, Chloe J, Bi, Guo-Hua, Solis, Oscar, Pignatelli, Marco, Bannon, Michael J, Xi, Zheng-Xiong, Tanda, Gianluigi, Michaelides, Michael

“…Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn ) also binds to the DAT, but the in vivo…”
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