Search Results - "Lam, Mei Ho"

Bioanalytical methods for the quantification of hydromorphone, fentanyl, norfentanyl, morphine, morphine-3ß-glucuronide and morphine-6ß-glucuronide in human plasma by de Bruijn, Peter, Kuip, Evelien J.M., Lam, Mei-Ho, Mathijssen, Ron H.J., Koolen, Stijn L.W.

“…•Sensitive methods for the quantitation of hydromorphone, morphine, fentanyl and the metabolites norfentanyl, morphine-3ß-glucuronide and…”
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Development and validation of an UPLC–MS/MS method for the quantification of tamoxifen and its main metabolites in human scalp hair by Drooger, Jan C., Jager, Agnes, Lam, Mei-Ho, den Boer, Mathilda D., Sleijfer, Stefan, Mathijssen, Ron H.J., de Bruijn, Peter

“…•Analysis of hair segments is a non-invasive method for measuring drug levels over time.•Adequate managing of hair samples before performing the analyses is…”
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Early cessation of the clinical development of LiPlaCis, a liposomal cisplatin formulation by de Jonge, Maja J.A, Slingerland, Marije, Loos, Walter J, Wiemer, Erik A.C, Burger, Herman, Mathijssen, Ron H.J, Kroep, Judith R, den Hollander, Margret A.G, van der Biessen, Diane, Lam, Mei-Ho, Verweij, Jaap, Gelderblom, Hans

“…Abstract Purpose To evaluate the safety and tolerability of LiPlaCis, a liposomal formulated platinum compound, in patients with solid tumours and to determine…”
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Bioanalytical method for the quantification of sunitinib and its n-desethyl metabolite SU12662 in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry by de Bruijn, Peter, Sleijfer, Stefan, Lam, Mei-Ho, Mathijssen, Ron H.J., Wiemer, Erik A.C., Loos, Walter J.

“…A rapid and sensitive ultra performance liquid chromatography/tandem mass spectrometry (UPLC–MS/MS) method has been developed and validated for the…”
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Quantification of cabazitaxel in human plasma by liquid chromatography/triple-quadrupole mass spectrometry: A practical solution for non-specific binding by de Bruijn, Peter, de Graan, Anne-Joy M., Nieuweboer, Annemieke, Mathijssen, Ron H.J., Lam, Mei-Ho, de Wit, Ronald, Wiemer, Erik A.C., Loos, Walter J.

“…► LC–MS/MS method for the quantitation of cabazitaxel in human plasma. ► Practical solution for non-specific binding. ► Validated according to the guidance of…”
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Validated bioanalytical method for the quantification of RGB-286638, a novel multi-targeted protein kinase inhibitor, in human plasma and urine by liquid chromatography/tandem triple-quadrupole mass spectrometry by de Bruijn, Peter, Moghaddam-Helmantel, Inge M. Ghobadi, de Jonge, Maja J.A., Meyer, Thorsten, Lam, Mei-Ho, Verweij, Jaap, Wiemer, Erik A.C., Loos, Walter J.

“…A rapid and sensitive liquid chromatography/tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the quantitative determination of…”
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Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry by Loos, Walter J., de Graan, Anne-Joy M., de Bruijn, Peter, van Schaik, Ron H.N., van Fessem, Marianne A.C., Lam, Mei-Ho, Mathijssen, Ron H.J., Wiemer, Erik A.C.

“…A rapid and sensitive ultra performance liquid chromatography/tandem mass spectrometry (UPLC–MS/MS) method has been developed and validated for the…”
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Augmentation of Endoxifen Exposure in Tamoxifen-Treated Women Following SSRI Switch by Binkhorst, Lisette, Bannink, Marjolein, de Bruijn, Peter, Ruit, Jan, Droogendijk, Helga, van Alphen, Robbert J., den Boer, Tilly D., Lam, Mei Ho, Jager, Agnes, van Gelder, Teun, Mathijssen, Ron H. J.

“…Background and Objective The anti-oestrogen tamoxifen requires metabolic activation to endoxifen by cytochrome P450 (CYP) enzymes, predominantly CYP2D6. Potent…”
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