Search Results - "Lam, KS"

A systematic review on the impact of diabetes mellitus on the ocular surface by Shih, K Co, Lam, K S-L, Tong, L

“…Diabetes mellitus is associated with extensive morbidity and mortality in any human community. It is well understood that the burden of diabetes is attributed…”
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Therapeutic cancer targeting peptides by Aina, Olulanu H., Sroka, Thomas C., Chen, Man-Ling, Lam, Kit S.

“…Antitumor monoclonal antibodies have shown clinical promise as cancer cell surface targeting agents. More tumor targeting antibodies are likely to be approved…”
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Biodistribution and pharmacokinetics of a telodendrimer micellar paclitaxel nanoformulation in a mouse xenograft model of ovarian cancer by Xiao, Wenwu, Luo, Juntao, Jain, Teesta, Riggs, John W, Tseng, Harry P, Henderson, Paul T, Cherry, Simon R, Rowland, Douglas, Lam, Kit S

“…A multifunctional telodendrimer-based micelle system was characterized for delivery of imaging and chemotherapy agents to mouse tumor xenografts. Previous…”
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Dystrophic Scoliosis in Neurofibromatosis and Rib-head Resection: A Case Report by KL, Chong, KS, Lam, Z, Zuki

“…Surgical management of scoliosis in Neurofibromatosis type I may be challenging at times especially when dealing with dystrophic curves. We highlight the…”
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Applications of One-Bead One-Compound Combinatorial Libraries and Chemical Microarrays in Signal Transduction Research by Lam, Kit S, Liu, Ruiwu, Miyamoto, Suzanne, Lehman, Alan L, Tuscano, Joseph M

“…The “one-bead-one-compound” (OBOC) combinatorial library method synthesizes millions of random compounds such that each bead displays only one compound. Bead…”
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Medical decompression of vertebral hydatidosis by LAM, K. S, FARAJ, A, MULHOLLAND, R. C, FINCH, R. G

“…A case report from one of the longest follow-up studies of survivors with spinal hydatid disease. This patient was treated with a combination of albendazole…”
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Identifying peptide ligands for cell surface receptors using cell-growth-on-bead assay and one-bead one-compound combinatorial library by LAU, Derick H, LINLANG GUO, RUIWU LIU, AIMIN SONG, CHUNKUI SHAO, LAM, Kit S

“…A cell-growth-on-bead assay was used to screen one-bead, one-compound combinatorial libraries for peptide ligands that attract attachment and growth of human…”
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Urban heat island diagnosis using ASTER satellite images and ‘in situ’ air temperature by Nichol, Janet E., Fung, Wing Yee, Lam, Ka-se, Wong, Man Sing

“…This study demonstrates that thermal satellite images combined with ‘in situ’ ground data can be used to examine models of heat island genesis and thus…”
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Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials by Potts, B C, Albitar, M X, Anderson, K C, Baritaki, S, Berkers, C, Bonavida, B, Chandra, J, Chauhan, D, Cusack, Jr, J C, Fenical, W, Ghobrial, I M, Groll, M, Jensen, P R, Lam, K S, Lloyd, G K, McBride, W, McConkey, D J, Miller, C P, Neuteboom, S T C, Oki, Y, Ovaa, H, Pajonk, F, Richardson, P G, Roccaro, A M, Sloss, C M, Spear, M A, Valashi, E, Younes, A, Palladino, M A

“…The proteasome has emerged as an important clinically relevant target for the treatment of hematologic malignancies. Since the Food and Drug Administration…”
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Upfront consolidation treatment with 131I‐mIbG followed by myeloablative chemotherapy and hematopoietic stem cell transplantation in high‐risk neuroblastoma by Feng, Jianhua, Cheng, Frankie WT, Leung, Alex WK, Lee, Vincent, Yeung, Eva WM, Ching Lam, Hoi, Cheung, Jeanny, Lam, Grace KS, Chow, Terry TW, Yan, Carol LS, Kong Li, Chi

“…Importance 131I‐metaiodobenzylguanidine (131I‐mIBG) has a significant targeted antitumor effect for neuroblastoma. However, currently there is a paucity of…”
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A convenient synthesis of coumarin-3-carboxylic acids via Knoevenagel condensation of Meldrum's acid with ortho-hydroxyaryl aldehydes or ketones by Song, Aimin, Wang, Xiaobing, Lam, Kit S

“…Coumarin-3-carboxylic acids were obtained in high yields with excellent purity from ortho-hydroxybenzaldehydes and Meldrum's acid after a 2 h reflux in…”
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A Novel Peptide-Based Encoding System for “One-Bead One-Compound” Peptidomimetic and Small Molecule Combinatorial Libraries by Liu, Ruiwu, Marik, Jan, Lam, Kit S

“…The “one-bead one-compound” (OBOC) combinatorial library method is highly efficient, especially when used with well-established on-bead binding or functional…”
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The “One-Bead-One-Compound” Combinatorial Library Method by Lam, Kit S, Lebl, Michal, Krchňák, Viktor

“…Lam et al give a brief description of the one-bead-one-compound concept and a detailed account of the chemistry used for library synthesis, various screening…”
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Peptide and Small Molecule Microarray for High Throughput Cell Adhesion and Functional Assays by Falsey, James R, Renil, M, Park, Steven, Li, Shijun, Lam, Kit S

“…A novel class of chemical microchips consisting of glass microscope slides was prepared for the covalent attachment of small molecule ligands and peptides…”
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Structure−Activity Relationship Studies of Salinosporamide A (NPI-0052), a Novel Marine Derived Proteasome Inhibitor by Macherla, Venkat R, Mitchell, Scott S, Manam, Rama Rao, Reed, Katherine A, Chao, Ta-Hsiang, Nicholson, Benjamin, Deyanat-Yazdi, Gordafaried, Mai, Bao, Jensen, Paul R, Fenical, William F, Neuteboom, Saskia T. C, Lam, Kin S, Palladino, Michael A, Potts, Barbara C. M

“…Salinosporamide A (1, NPI-0052) is a potent proteasome inhibitor in development for treating cancer. In this study, a series of analogues was assayed for…”
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Chemical Xenobiotics and Mitochondrial Autoantigens in Primary Biliary Cirrhosis: Identification of Antibodies against a Common Environmental, Cosmetic, and Food Additive, 2-Octynoic Acid by Amano, Katsushi, Leung, Patrick S. C, Rieger, Roman, Quan, Chao, Wang, Xiaobing, Marik, Jan, Suen, Yat Fan, Kurth, Mark J, Nantz, Michael H, Ansari, Aftab A, Lam, Kit S, Zeniya, Mikio, Matsuura, Eiji, Coppel#, Ross L, Gershwin, M. Eric

“…Emerging evidence has suggested environmental factors as causative agents in the pathogenesis of primary biliary cirrhosis (PBC). We have hypothesized that in…”
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Management Outcome and the Role of Manipulation in Slipped Capital Femoral Epiphysis by Lim, YJ, Lam, KS, Lim, KBL, Mahadev, A, Lee, EH

“…Purpose. To examine and compare treatment outcomes for slipped capital femoral epiphysis (SCFE). Methods. 24 patients with acute or acute-on-chronic SCFE…”
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Traction and Spica Casting for Closed Femoral Shaft Fractures in Children by Lee, YHD, Lim, KBL, Gao, GX, Mahadev, A, Lam, KS, Tan, SB, Lee, EH

“…Purpose. To evaluate the treatment outcome of skin traction followed by spica casting for closed femoral shaft fractures in children. Methods. Between…”
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Bisphenol A and other bisphenol analogues including BPS and BPF in surface water samples from Japan, China, Korea and India by Yamazaki, Eriko, Yamashita, Nobuyoshi, Taniyasu, Sachi, Lam, James, Lam, Paul K.S., Moon, Hyo-Bang, Jeong, Yunsun, Kannan, Pranav, Achyuthan, Hema, Munuswamy, Natesan, Kannan, Kurunthachalam

“…Concentrations of eight bisphenol analogues (BPs) including BPA, BPS, and BPF were determined in surface waters collected from select rivers in Japan, Korea,…”
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Prospective Evaluation of Cancer Clinical Trial Accrual Patterns: Identifying Potential Barriers to Enrollment by Lara, Jr, P N, Higdon, R, Lim, N, Kwan, K, Tanaka, M, Lau, D H, Wun, T, Welborn, J, Meyers, F J, Christensen, S, O'Donnell, R, Richman, C, Scudder, S A, Tuscano, J, Gandara, D R, Lam, K S

“…Well-conducted cancer clinical trials are essential for improving patient outcomes. Unfortunately, only 3% of new cancer patients participate in clinical…”
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