Search Results - "Lam, K.W."

Effective mRNA pulmonary delivery by dry powder formulation of PEGylated synthetic KL4 peptide by Qiu, Yingshan, Man, Rico C.H., Liao, Qiuying, Kung, Keshia L.K., Chow, Michael Y.T., Lam, Jenny K.W.

“…[Display omitted] •PEG12KL4 peptide is a promising mRNA delivery vector for pulmonary delivery.•Inhalable mRNA dry powder can be prepared by spray drying and…”
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Objective monitoring tools for improved management of childhood asthma by Au-Doung, Phillip L W, Chan, Jason C H, Kui, Oliver Y H, Ho, Marco K Y, Cheung, Yin Ting, Lam, Jenny K W, Chan, Hak-Kim, Brannan, John, Chan, Kate C C, Li, Albert M, Leung, Sharon S Y

“…Asthma is a common chronic disease amongst children. Epidemiological studies showed that the mortality rate of asthma in children is still high worldwide…”
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Chemical–physical properties and cytotoxicity of N-decanoyl amino acid-based surfactants: Effect of polar heads by Perinelli, Diego R., Casettari, Luca, Cespi, Marco, Fini, Francesco, Man, Dede K.W., Giorgioni, Gianfabio, Canala, Silvia, Lam, Jenny K.W., Bonacucina, Giulia, Palmieri, Giovanni F.

“…[Display omitted] •N-Decanoyl aminoacyl derivates were analyzed at physiological pH in comparison to SDS.•Toxicological profile was assessed by MTT, LDH,…”
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Dry Powder Formulation of Plasmid DNA and siRNA for Inhalation by Chow, Michael Y T, Lam, Jenny K W

“…Nucleic acid therapeutics has huge potential for the treatment of a wide range of diseases including respiratory diseases. Plasmid DNA (pDNA) and small…”
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Pulmonary delivery of rifampicin microspheres using lower generation polyamidoamine dendrimers as a carrier by Rajabnezhad, Saeid, Casettari, Luca, Lam, Jenny K.W., Nomani, Alireza, Torkamani, Mohammad Reza, Palmieri, Giovanni Filippo, Rajabnejad, Mohammad Reza, Darbandi, Mohammad Ali

“…Different generations (G1, G2 and G3) of polyamidoamine dendrimers (PAMAM) were synthesized and co-spray dried with rifampicin to produce inhalable…”
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Formulation of pH responsive peptides as inhalable dry powders for pulmonary delivery of nucleic acids by Liang, Wanling, Kwok, Philip C.L., Chow, Michael Y.T., Tang, Patricia, Mason, A. James, Chan, Hak-Kim, Lam, Jenny K.W.

“…[Display omitted] Nucleic acids have the potential to be used as therapies or vaccines for many different types of disease, but delivery remains the most…”
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Peak early diastolic mitral annulus velocity by tissue Doppler imaging adds independent and incremental prognostic value by Wang, Mei, Yip, Gabriel W.K, Wang, Angela Y.M, Zhang, Yan, Ho, Pik Yuk, Tse, Mui Kiu, Lam, Peggo K.W, Sanderson, John E

“…The aim of this study was to ascertain if left ventricular mitral annulus velocities measured by tissue Doppler imaging (TDI) are more powerful predictors of…”
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Effective endogenous gene silencing mediated by pH responsive peptides proceeds via multiple pathways by Lam, Jenny K.W., Liang, Wanling, Lan, Yun, Chaudhuri, Poulami, Chow, Michael Y.T., Witt, Katarzyna, Kudsiova, Laila, Mason, A. James

“…Cationic amphipathic histidine rich peptides possess high plasmid DNA and siRNA delivery capabilities. To further understand the pH responsive siRNA delivery…”
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Effects of Differential Glycosylation of Glycodelins on Lymphocyte Survival by Lee, Cheuk-Lun, Pang, Poh-Choo, Yeung, William S.B., Tissot, Bérangère, Panico, Maria, Lao, Terence T.H., Chu, Ivan K., Lee, Kai-Fai, Chung, Man-Kin, Lam, Kevin K.W., Koistinen, Riitta, Koistinen, Hannu, Seppälä, Markku, Morris, Howard R., Dell, Anne, Chiu, Philip C.N.

“…Glycodelin is a human glycoprotein with four reported glycoforms, namely glycodelin-A (GdA), glycodelin-F (GdF), glycodelin-C (GdC), and glycodelin-S (GdS)…”
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Effects of Native Human Zona Pellucida Glycoproteins 3 and 4 on Acrosome Reaction and Zona Pellucida Binding of Human Spermatozoa by Chiu, Philip C. N, Wong, Ben S. T, Chung, Man-Kin, Lam, Kevin K. W, Pang, Ronald T. K, Lee, Kai-Fai, Sumitro, S. B, Gupta, S. K, Yeung, William S. B

“…Acrosome reaction is crucial to the penetration of spermatozoa through the zona pellucida (ZP). Glycosylation of ZP glycoproteins is important in…”
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Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage by Huang, Venus W., B.Sc, Zhao, Weie, M.B.B.S, Lee, Cheuk-Lun, Ph.D, Lee, Cherie Y.L., Ph.D, Lam, Kevin K.W., Ph.D, Ko, Jennifer K.Y., M.B.B.S, Yeung, William S.B., Ph.D, Ho, Pak-Chung, M.D, Chiu, Philip C.N., Ph.D

“…Objective To study the potential protective action in vitro of oviductal epithelial cell membrane proteins against oxidative damage in human spermatozoa…”
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MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells by Pang, Ronald T.K., Leung, Carmen O.N., Ye, Tian-Min, Liu, Weimin, Chiu, Philip C.N., Lam, Kevin K.W., Lee, Kai-Fai, Yeung, William S.B.

“…MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of other genes by transcriptional inhibition or translational repression. miR-34a is…”
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AP044 Development of nurse initiated defibrillation programme to improve the clinical outcome of patients with cardiac arrest by Lam, K.W, Au Yeung, K.W, Lai, K.Y

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Spray freeze drying of small nucleic acids as inhaled powder for pulmonary delivery by Liang, Wanling, Chan, Alan Y.L., Chow, Michael Y.T., Lo, Fiona F.K., Qiu, Yingshan, Kwok, Philip C.L., Lam, Jenny K.W.

“…The therapeutic potential of small nucleic acids such as small interfering RNA (siRNA) to treat lung diseases has been successfully demonstrated in many in…”
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Glycodelin-A as a modulator of trophoblast invasion by Lam, Kevin K.W., Chiu, Philip C.N., Chung, Man-Kin, Lee, Cheuk-Lun, Lee, Kai-Fai, Koistinen, Riitta, Koistinen, Hannu, Seppala, Markku, Ho, Pak-Chung, Yeung, William S.B.

“…BACKGROUND Trophoblast invasion is crucial to placentation. The relationship between decidual glycodelin-A and trophoblast invasion is not known. METHODS…”
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The roles of protein disulphide isomerase family A, member 3 (ERp57) and surface thiol/disulphide exchange in human spermatozoa–zona pellucida binding by Wong, Chi-Wai, Lam, Kevin K.W., Lee, Cheuk-Lun, Yeung, William S.B., Zhao, Wei E., Ho, Pak-Chung, Ou, Jian-Ping, Chiu, Philip C.N.

“…Abstract STUDY QUESTION Are multimeric sperm plasma membrane protein complexes, ERp57 and sperm surface thiol content involved in human spermatozoa–zona…”
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Biomedical applications of amino acid-modified chitosans: A review by Casettari, Luca, Vllasaliu, Driton, Lam, Jenny K.W, Soliman, Mahmoud, Illum, Lisbeth

“…Abstract The presence of reactive primary amines in the backbone structure of chitosan, enables the derivatisation with different functional groups and thereby…”
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Identification of CD147 (basigin) as a mediator of trophoblast functions by Lee, Cheuk-Lun, Lam, Maggie P.Y., Lam, Kevin K.W., Leung, Carmen O.N., Pang, Ronald T.K., Chu, Ivan K., Wan, Tiffany H.L., Chai, Joyce, Yeung, William S.B., Chiu, Philip C.N.

“…STUDY QUESTION Does CD147 regulate trophoblast functions in vitro? SUMMARY ANSWER CD147 exists as a receptor complex on human trophoblast and regulates the…”
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The identity of zona pellucida receptor on spermatozoa: An unresolved issue in developmental biology by Chiu, Philip C.N., Lam, Kevin K.W., Wong, Rachel C.W., Yeung, William S.B.

“…•The plasma membrane of spermatozoa is a dynamic structure with diverse microdomains.•Sperm plasma membrane undergoes dramatic changes during sperm maturation…”
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Glycodelin-A Stimulates Interleukin-6 Secretion by Human Monocytes and Macrophages through L-selectin and the Extracellular Signal-regulated Kinase Pathway by Lee, Cheuk-Lun, Lam, Eve Y.F., Lam, Kevin K.W., Koistinen, Hannu, Seppälä, Markku, Ng, Ernest H.Y., Yeung, William S.B., Chiu, Philip C.N.

“…Macrophages represent the second major type of decidual leukocytes at the fetomaternal interface. Changes in macrophage number and activity are associated with…”
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