Search Results - "Lam, E.W"

1060 SUMOylation of FOXM1 Regulates its Activity and Cytotoxic Drug Response by Lam, E.W, Myatt, S.S

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729 FOXM1 Regulates BRIP1 Expression in Breast Cancer Epirubicin Treatment and Resistance by Monteiro, L, Lam, E.W

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164: Interplay between EMT-inducers and miRNAs during breast tumorigenesis by Moyret-Lalle, C, Vitton-Méa, B, Ruiz, E, Hermann, C, Lam, E.W, Puisieux, A

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728 The Role of FOXM1 and NBS1 in DNA Double Strand Breaks Repair and Epirubicin Resistance by Khongkow, P, Karunarathna, H.U, Lam, E.W

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677 FOXO3a Represses VEGF Expression Through FOXM1-dependent and -independent Mechanisms by Gomes, A.R, Karadedou, C.T, Lam, E.W

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FOXO transcription factors: key regulators of cell fate by Lam, E W-F, Francis, R E, Petkovic, M

“…FOXO (forkhead box O) transcription factors are crucial regulators of cell fate. This function of FOXO proteins relies on their ability to control diverse and…”
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732 The p38 MAPK2-MK2 Signalling Axis is Central in the Regulation of E2F1 and FOXM1 by Epirubicin by Koo, C.Y, de Olano, N, Monteiro, L, Pinto, P.H, Gomes, A.R, Aligue, R, Lam, E.W

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Indoor 3D Localization with Low-Cost LiFi Components by Lam, E.W., Little, T.D.C.

“…Indoor positioning or localization is an enabling technology expected to have a profound impact on mobile applications. Various modalities of radio frequency,…”
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Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance by Khongkow, P, Gomes, A R, Gong, C, Man, E P S, Tsang, J W-H, Zhao, F, Monteiro, L J, Coombes, R C, Medema, R H, Khoo, U S, Lam, E W-F

“…FOXM1 has been implicated in taxane resistance, but the molecular mechanism involved remains elusive. In here, we show that FOXM1 depletion can sensitize…”
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OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance by Karunarathna, U, Kongsema, M, Zona, S, Gong, C, Cabrera, E, Gomes, A R, Man, E P S, Khongkow, P, Tsang, J W-H, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F

“…The forkhead transcription factor FOXM1 has a key role in DNA damage response, and its deregulated overexpression is associated with genotoxic drug resistance…”
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Many forks in the path: cycling with FoxO by Ho, K K, Myatt, S S, Lam, E W-F

“…FoxO transcription factors are an evolutionary conserved subfamily of the forkhead transcription factors, characterized by the forkhead DNA-binding domain…”
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Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers by Siu, M K Y, Wong, E S Y, Kong, D S H, Chan, H Y, Jiang, L, Wong, O G W, Lam, E W-F, Chan, K K L, Ngan, H Y S, Le, X-F, Cheung, A N

“…Ovarian cancer is the most lethal of all gynecological malignancies, and the identification of novel prognostic and therapeutic targets for ovarian cancer is…”
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FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance by Khongkow, P, Karunarathna, U, Khongkow, M, Gong, C, Gomes, A R, Yagüe, E, Monteiro, L J, Kongsema, M, Zona, S, Man, E P S, Tsang, J W-H, Coombes, R C, Wu, K-J, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F

“…FOXM1 is implicated in genotoxic drug resistance but its mechanism of action remains elusive. We show here that FOXM1-depletion can sensitize breast cancer…”
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FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer by Karadedou, C T, Gomes, A R, Chen, J, Petkovic, M, Ho, K-K, Zwolinska, A K, Feltes, A, Wong, S Y, Chan, K Y K, Cheung, Y-N, Tsang, J W H, Brosens, J J, Khoo, U-S, Lam, E W-F

“…Vascular endothelial growth factor (VEGF) has a central role in breast cancer development and progression, but the mechanisms that control its expression are…”
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FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer by Gong, C, Fujino, K, Monteiro, L J, Gomes, A R, Drost, R, Davidson-Smith, H, Takeda, S, Khoo, U S, Jonkers, J, Sproul, D, Lam, E W-F

“…FOXA1 expression correlates with the breast cancer luminal subtype and patient survival. RNA and protein analysis of a panel of breast cancer cell lines…”
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The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment by Monteiro, L J, Khongkow, P, Kongsema, M, Morris, J R, Man, C, Weekes, D, Koo, C-Y, Gomes, A R, Pinto, P H, Varghese, V, Kenny, L M, Charles Coombes, R, Freire, R, Medema, R H, Lam, E W-F

“…FOXM1 is implicated in genotoxic drug resistance but its role and mechanism of action remain unclear. Here, we establish that γH2AX foci, indicative of DNA…”
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FOXM1 is a transcriptional target of ERα and has a critical role in breast cancer endocrine sensitivity and resistance by Millour, J, Constantinidou, D, Stavropoulou, A V, Wilson, M S C, Myatt, S S, Kwok, J M-M, Sivanandan, K, Coombes, R C, Medema, R H, Hartman, J, Lykkesfeldt, A E, Lam, E W-F

“…In this study, we investigated the regulation of FOXM1 expression by estrogen receptor α (ERα) and its role in hormonal therapy and endocrine resistance. FOXM1…”
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The FoxO-BNIP3 axis exerts a unique regulation of mTORCl and cell survival under energy stress by Lin, A, Yao, J, Zhuang, L, Wang, D, Han, J, Lam, E.W.-F, Gan, B

“…Normal cells possess adaptive mechanisms to couple energy availability with cell growth (cell size increase) and survival, and imbalances are associated with…”
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Mechanism and functional consequences of loss of FOXO1 expression in endometrioid endometrial cancer cells by Goto, T., Takano, M., Albergaria, André, Briese, J., Pomeranz, K. M., Cloke, B., Fusi, L., Feroze-Zaidi, F., Maywald, N., Sajin, M.

“…The forkhead transcription factor FOXO1, a downstream target of phosphatidylinositol-3-kinase/Akt signalling pathway, regulates cyclic differentiation and…”
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The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress by Lin, A, Yao, J, Zhuang, L, Wang, D, Han, J, Lam, E.W.-F, Gan, B

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