Search Results - "Lam, Christopher Wai Kei"

Pomiferin targets SERCA, mTOR, and P-gp to induce autophagic cell death in apoptosis-resistant cancer cells, and reverses the MDR phenotype in cisplatin-resistant tumors in vivo by Qu, Yuan-Qing, Song, Lin-Lin, Xu, Su-Wei, Yu, Margaret Sum Yee, Kadioglu, Onat, Michelangeli, Francesco, Law, Betty Yuen Kwan, Efferth, Thomas, Lam, Christopher Wai-Kei, Wong, Vincent Kam Wai

“…Drug resistance in cancer has been classified as innate resistance or acquired resistance, which were characterized by apoptotic defects and ABC transporters…”
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Skewed inflammation is associated with aberrant interleukin‐37 signaling pathway in atopic dermatitis by Hou, Tianheng, Tsang, Miranda Sin‐Man, Chu, Ida Miu‐Ting, Kan, Lea Ling‐Yu, Hon, Kam‐Lun, Leung, Ting‐Fan, Lam, Christopher Wai‐Kei, Wong, Chun‐Kwok

“…Background Atopic dermatitis (AD) is a severe global burden on physical, physiological, and mental health. The role of IL‐37, a fundamental inhibitor of…”
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Advanced Carbon‐Based Anodes for Potassium‐Ion Batteries by Wu, Xuan, Chen, Yanli, Xing, Zheng, Lam, Christopher Wai Kei, Pang, Su‐Seng, Zhang, Wei, Ju, Zhicheng

“…The ever‐increasing demand for large‐scale energy storage systems requires novel battery technologies with low‐cost and sustainable properties. Due to…”
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Early Enhanced Expression of Interferon-Inducible Protein-10 (CXCL-10) and Other Chemokines Predicts Adverse Outcome in Severe Acute Respiratory Syndrome by Tang, Nelson Leung-Sang, Chan, Paul Kay-Sheung, Wong, Chun-Kwok, To, Ka-Fai, Wu, Alan Ka-Lun, Sung, Ying-Man, Hui, David Shu-Cheong, Sung, Joseph Jao-Yiu, Lam, Christopher Wai-Kei

“…Exaggerated activation of cytokines/chemokines has been proposed as a factor in adverse outcome of severe acute respiratory syndrome (SARS). Previous studies…”
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Consumption of Sugar-Sweetened Beverages Has a Dose-Dependent Effect on the Risk of Non-Alcoholic Fatty Liver Disease: An Updated Systematic Review and Dose-Response Meta-Analysis by Chen, Hongwei, Wang, Jue, Li, Zheng, Lam, Christopher Wai Kei, Xiao, Ying, Wu, Qibiao, Zhang, Wei

“…Non-alcoholic fatty liver disease (NAFLD) is a serious health problem, but the dose-response relationship between sugar-sweetened beverages (SSBs) and NAFLD…”
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HM30181A, a potent P-glycoprotein inhibitor, potentiates the absorption and in vivo antitumor efficacy of paclitaxel in an orthotopic brain tumor model by Zeng, Wu, Kwan Law, Betty Yuen, Wai Wong, Vincent Kam, Bik Chan, Denise So, Fai Mok, Simon Wing, Ying Gao, Joyce Jia, Yan Ho, Rebecca Ka, Liang, Xu, Li, Jia Hao, Lee, Ming Tsung, Yoon, Weng Li, Smolinski, Michael P, Nam Lau, Johnson Yiu, Kei Lam, Christopher Wai, Fok, Manson

“…Delivery of chemotherapeutic drugs to the brain has remained a major obstacle in the treatment of glioma, owing to the presence of the blood-brain barrier and…”
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Is a single time point C-reactive protein predictive of outcome in peritoneal dialysis patients? by YEE-MOON WANG, Angela, WOO, Jean, WAI-KEI LAM, Christopher, MEI WANG, MAN-MEI SEA, Mandy, LUI, Siu-Fai, KAM-TAO LI, Philip, SANDERSON, John

“…C-reactive protein is the prototype marker of inflammation and has been shown to predict mortality in hemodialysis patients. However, it remains uncertain as…”
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Effect of Paricalcitol on Left Ventricular Mass and Function in CKD—The OPERA Trial by WANG, Angela Yee-Moon, FANG FANG, YU, Cheuk-Man, CHAN, John, WEN, Yue-Yi, SHANG QING, CHAN, Iris Hiu-Shuen, LO, Gladys, LAI, Kar-Neng, LO, Wai-Kei, LAM, Christopher Wai-Kei

“…Vitamin D seems to protect against cardiovascular disease, but the reported effects of vitamin D on patient outcomes in CKD are controversial. We conducted a…”
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IL-37 Ameliorating Allergic Inflammation in Atopic Dermatitis Through Regulating Microbiota and AMPK-mTOR Signaling Pathway-Modulated Autophagy Mechanism by Hou, Tianheng, Sun, Xiaoyu, Zhu, Jing, Hon, Kam-Lun, Jiang, Peiyong, Chu, Ida Miu-Ting, Tsang, Miranda Sin-Man, Lam, Christopher Wai-Kei, Zeng, Huasong, Wong, Chun-Kwok

“…Interaction between eosinophils and dermal fibroblasts is essential for provoking allergic inflammation in atopic dermatitis (AD). co-culture of human…”
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The Diagnostic Utility of Cardiac Biomarkers in Dialysis Patients by Wang, Angela Yee-Moon, Wai-Kei Lam, Christopher

“…Mortality in dialysis patients remains high due to excessive cardiovascular disease burden from coronary artery disease, left ventricular hypertrophy, and…”
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Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma by Sun, Xiaoyu, Hou, Tianheng, Cheung, Edwin, Iu, Tiffany Nga-Teng, Tam, Victor Wai-Hou, Chu, Ida Miu-Ting, Tsang, Miranda Sin-Man, Chan, Paul Kay-Sheung, Lam, Christopher Wai-Kei, Wong, Chun-Kwok

“…We elucidated the anti-inflammatory mechanisms of IL-38 in allergic asthma. Human bronchial epithelial cells and eosinophils were cocultured upon stimulation…”
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1,2,3,4,6-Pentagalloyl Glucose, a RBD-ACE2 Binding Inhibitor to Prevent SARS-CoV-2 Infection by Chen, Rui Hong, Yang, Li Jun, Hamdoun, Sami, Chung, Sookja Kim, Lam, Christopher Wai-Kei, Zhang, Kai Xi, Guo, Xiaoling, Xia, Chenglai, Law, Betty Yuen Kwan, Wong, Vincent Kam Wai

“…The outbreak of SARS-CoV-2 virus caused more than 80,155,187 confirmed COVID-19 cases worldwide, which has posed a serious threat to global public health and…”
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Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections by Gao, Xun, Chan, Paul Kay Sheung, Lui, Grace Chung Yan, Hui, David Shu Cheong, Chu, Ida Miu-Ting, Sun, Xiaoyu, Tsang, Miranda Sin-Man, Chan, Ben Chung Lap, Lam, Christopher Wai-Kei, Wong, Chun-Kwok

“…Interleukin-38 has recently been shown to have anti-inflammatory properties in lung inflammatory diseases. However, the effects of IL-38 in viral pneumonia…”
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Prognostic Value of Plasma Myeloperoxidase in ESRD Patients by Wang, Angela Yee-Moon, MD, PhD, FRCP, Lam, Christopher Wai-Kei, PhD, FACB, Chan, Iris Hiu-Shuen, PhD, Wang, Mei, PhD, Lui, Siu-Fai, FRCP, Sanderson, John E., MD, FRCP

“…Background Myeloperoxidase (MPO) has been suggested to have a role in atherosclerosis through its strong oxidative capacity. We hypothesized that MPO level may…”
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The flavonoids of Sophora flavescens exerts anti‐inflammatory activity via promoting autophagy of Bacillus Calmette‐Guérin‐stimulated macrophages by Kan, Lea Ling‐Yu, Liu, Dehua, Chan, Ben Chung‐Lap, Tsang, Miranda Sin‐Man, Hou, Tianheng, Leung, Ping Chung, Lam, Christopher Wai‐Kei, Wong, Chun Kwok

“…Tuberculosis (TB), a highly infectious air‐borne disease, has remained a global health problem. Conventional treatment and preventions such as antibiotics and…”
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Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia by Tomlinson, Brian, Patil, Nivritti Gajanan, Fok, Manson, Lam, Christopher Wai Kei

“…Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do not reach…”
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IL-37 Targets TSLP-Primed Basophils to Alleviate Atopic Dermatitis by Hou, Tianheng, Tsang, Miranda Sin-Man, Kan, Lea Ling-Yu, Li, Peiting, Chu, Ida Miu-Ting, Lam, Christopher Wai-Kei, Wong, Chun-Kwok

“…Atopic dermatitis (AD) represents a severe global burden on physical, physiological and mental health. Innate immune cell basophils are essential for provoking…”
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The Immuno-Modulatory Activities of Pentaherbs Formula on Ovalbumin-Induced Allergic Rhinitis Mice via the Activation of Th1 and Treg Cells and Inhibition of Th2 and Th17 Cells by Li, Peiting, Tsang, Miranda Sin-Man, Kan, Lea Ling-Yu, Hou, Tianheng, Hon, Sharon Sze-Man, Chan, Ben Chung-Lap, Chu, Ida Miu-Ting, Lam, Christopher Wai-Kei, Leung, Ping-Chung, Wong, Chun-Kwok

“…Allergic rhinitis (AR) is a highly prevalent allergic disease induced by immunoglobulin (Ig) E-mediated hypersensitivity reaction at the nasal epithelium…”
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FAK-mediated activation of ERK for eosinophil migration: a novel mechanism for infection-induced allergic inflammation by Cheung, Phyllis Fung-Yi, Wong, Chun-Kwok, Ip, Wai-Ki, Lam, Christopher Wai-Kei

“…Bacterial and viral infections often induce the exacerbation of allergic diseases. In this study, we investigated the activation of human eosinophils by…”
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NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation by Jiao, Delong, Wong, Chun-Kwok, Qiu, Huai-Na, Dong, Jie, Cai, Zhe, Chu, Man, Hon, Kam-Lun, Tsang, Miranda Sin-Man, Lam, Christopher Wai-Kei

“…The skin of patients with atopic dermatitis （AD） has a unique predisposition for colonization by Staphylococcus aureus （S. aureus）, which contributes to the…”
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