Search Results - "Lam, Bonnie Y.K"
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Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01-12-2019)“…Many consequences of cerebrovascular disease are identifiable by magnetic resonance imaging (MRI), but variation in methods limits multicenter studies and…”
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Delayed-onset dementia after stroke or transient ischemic attack
Published in Alzheimer's & dementia (01-11-2016)“…Abstract Introduction Patients surviving stroke without immediate dementia are at high risk of delayed-onset dementia. Mechanisms underlying delayed-onset…”
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Machine-learning derived MRI-based atrophy biomarker predicts long-term cognitive decline in stroke or transient ischemic attack
Published in Cerebral circulation - cognition and behavior (2024)“…Alzheimer's disease-resemblance atrophy index (AD-RAI) is a machine-learning derived MRI-based brain atrophy biomarker that is valid in predicting cognitive…”
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Can transcranial Doppler ultrasound be used for screening cerebral small vessel diseases in the community?
Published in Journal of the neurological sciences (15-11-2019)“…AbstractObjectivesElderly persons harbouring severe white matter hyperintensity (WMH), a radiological manifestation of cerebral small vessel disease (SVD),…”
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Efficacy and safety of cilostazol in decreasing progression of cerebral white matter hyperintensities—A randomized controlled trial
Published in Alzheimer's & dementia : translational research & clinical interventions (2022)“…Introduction Cerebral small vessel disease (SVD) is an important cause of dementia that lacks effective treatment. We evaluated the efficacy and safety of…”
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RISK FACTOR PROFILES PREDICTING DELAYED VASCULAR COGNITIVE IMPAIRMENT IN YOUNG AND OLD ISCHEMIC STROKE SURVIVORS
Published in Alzheimer's & dementia (01-07-2017)Get full text
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Neuroimaging standards for research into small vessel disease—advances since 2013
Published in Lancet neurology (01-07-2023)“…Cerebral small vessel disease (SVD) is common during ageing and can present as stroke, cognitive decline, neurobehavioural symptoms, or functional impairment…”
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Early-onset and delayed-onset poststroke dementia — revisiting the mechanisms
Published in Nature reviews. Neurology (01-03-2017)“…Key Points Early-onset poststroke dementia (PSD) depends on a complex interplay between features of the stroke lesion, such as large size or strategic site,…”
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Machine‐learning derived MRI‐based atrophy biomarker predicts long‐term cognitive decline in stroke or transient ischemic attack
Published in Alzheimer's & dementia (01-12-2023)“…Background Alzheimer’s disease‐resemblance atrophy index (AD‐RAI) is a machine‐learning derived MRI‐based brain atrophy biomarker that is valid in predicting…”
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Machine‐learning derived MRI‐based atrophy biomarker predicts long‐term cognitive decline in stroke or transient ischemic attack
Published in Alzheimer's & dementia (01-12-2023)“…Background Alzheimer’s disease‐resemblance atrophy index (AD‐RAI) is a machine‐learning derived MRI‐based brain atrophy biomarker that is valid in predicting…”
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Comparing machine learning-derived MRI-based and blood-based neurodegeneration biomarkers in predicting syndromal conversion in early AD
Published in Alzheimer's & dementia (01-11-2023)“…We compared the machine learning-derived, MRI-based Alzheimer's disease (AD) resemblance atrophy index (AD-RAI) with plasma neurofilament light chain (NfL)…”
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Association between amyloid, tau and cerebral small vessel disease
Published in Alzheimer's & dementia (01-06-2023)“…Background Controversy exists with respect to the etiological role of cerebral small vessel disease (CSVD) in Alzheimer’s disease (AD). We thus evaluated the…”
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Longitudinal white matter changes in frontotemporal dementia subtypes
Published in Human brain mapping (01-07-2014)“…Frontotemporal dementia is a degenerative brain condition characterized by focal atrophy affecting the frontal and temporal lobes predominantly. Changes in…”
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Mapping the contributing factors of depression in community elders: Neuroimaging / Optimal neuroimaging measures for early detection
Published in Alzheimer's & dementia (01-12-2020)“…Abstract Background The contributing factors of depressive symptoms in elderlies are not known quite well. This study aims to investigate the clinical and…”
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Mapping the contribution of clinical risk factors and MRI‐based imaging features to cognitive impairment in community elders
Published in Alzheimer's & dementia (01-12-2020)“…Background It is still not clear about the clinical risk factors of cognitive impairment in community elderlies. Although many studies have investigated the…”
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Mapping the contributing factors of depression in community elders
Published in Alzheimer's & dementia (01-12-2020)“…Background The contributing factors of depressive symptoms in elderlies are not known quite well. This study aims to investigate the clinical and neuroimaging…”
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Mapping the contribution of clinical risk factors and MRI‐based imaging features to cognitive impairment in community elders: Neuroimaging / Optimal neuroimaging measures for early detection
Published in Alzheimer's & dementia (01-12-2020)“…Abstract Background It is still not clear about the clinical risk factors of cognitive impairment in community elderlies. Although many studies have…”
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Development and validation of a risk score (CHANGE) for cognitive impairment after ischemic stroke
Published in Scientific reports (29-09-2017)“…Post-stroke cognitive impairment (PSCI) warrants early detection and management. We sought to develop a risk score for screening patients at bedside for risk…”
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