Search Results - "Lalonde, Robert L"

Multiple embryonic sources converge to form the pectoral girdle skeleton in zebrafish by Kuroda, Shunya, Lalonde, Robert L., Mansour, Thomas A., Mosimann, Christian, Nakamura, Tetsuya

“…The morphological transformation of the pectoral/shoulder girdle is fundamental to the water-to-land transition in vertebrate evolution. Although previous…”
Get full text

Effects of fin fold mesenchyme ablation on fin development in zebrafish by Lalonde, Robert L, Akimenko, Marie-Andrée

“…The evolution of the tetrapod limb involved an expansion and elaboration of the endoskeletal elements, while the fish fin rays were lost. Loss of fin-specific…”
Get full text

Lateral thinking in syndromic congenital cardiovascular disease by Kocere, Agnese, Lalonde, Robert L, Mosimann, Christian, Burger, Alexa

“…Syndromic birth defects are rare diseases that can present with seemingly pleiotropic comorbidities. Prime examples are rare congenital heart and…”
Get full text

Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state by Kherdjemil, Yacine, Lalonde, Robert L., Sheth, Rushikesh, Dumouchel, Annie, de Martino, Gemma, Pineault, Kyriel M., Wellik, Deneen M., Stadler, H. Scott, Akimenko, Marie-Andrée, Kmita, Marie

“…The mutually exclusive expression of the Hoxa11 and Hoxa13 genes is required for pentadactyl (five-digit) limbs and is proposed to have contributed to the…”
Get full text

Differential actinodin1 regulation in embryonic development and adult fin regeneration in Danio rerio by Phan, Hue-Eileen, Northorp, Marissa, Lalonde, Robert L, Ngo, Dung, Akimenko, Marie-Andrée

“…Actinotrichia are the first exoskeletal elements formed during zebrafish fin development. These rigid fibrils serve as skeletal support for the fin fold and as…”
Get full text

Contributions of 5'HoxA/D regulation to actinodin evolution and the fin-to-limb transition by Lalonde, Robert L, Akimenko, Marie-Andrée

“…The evolution of tetrapod limbs from paired fish fins comprised major changes to the appendicular dermal and endochondral skeleton. Fish fin rays were lost,…”
Get full text

Functional comparison of human ACVR1 and zebrafish Acvr1l FOP‐associated variants in embryonic zebrafish by Lalonde, Robert L., Nicolas, Hannah A., Cutler, Rowan S., Pantekidis, Irene, Zhang, Weibo, Yelick, Pamela C.

“…Background Fibrodysplasia ossificans progressiva (FOP), a rare disease characterized by progressive heterotopic ossification of muscle and connective tissues,…”
Get full text

Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole‐Exome Sequencing in a Patient with Delayed‐Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1R206H‐Specific Human Cellular and Zebrafish Models by Wentworth, Kelly L., Lalonde, Robert L., Groppe, Jay C., Brewer, Niambi, Moody, Tania, Hansberry, Steven, Taylor, Kimberly E., Shore, Eileen M., Kaplan, Frederick S., Pignolo, Robert J., Yelick, Pamela C., Hsiao, Edward C.

“…ABSTRACT Bone morphogenetic protein (BMP) signaling is critical in skeletal development. Overactivation can trigger heterotopic ossification (HO) as in…”
Get full text

Heterogeneity and genomic loci of ubiquitous transgenic Cre reporter lines in zebrafish by Lalonde, Robert L., Kemmler, Cassie L., Riemslagh, Fréderike W., Aman, Andrew J., Kresoja‐Rakic, Jelena, Moran, Hannah R., Nieuwenhuize, Susan, Parichy, David M., Burger, Alexa, Mosimann, Christian

“…Background The most‐common strategy for zebrafish Cre/lox‐mediated lineage labeling experiments combines ubiquitously expressed, lox‐based Switch reporter…”
Get full text

A median fin derived from the lateral plate mesoderm and the origin of paired fins by Tzung, Keh-Weei, Lalonde, Robert L., Prummel, Karin D., Mahabaleshwar, Harsha, Moran, Hannah R., Stundl, Jan, Cass, Amanda N., Le, Yao, Lea, Robert, Dorey, Karel, Tomecka, Monika J., Zhang, Changqing, Brombacher, Eline C., White, William T., Roehl, Henry H., Tulenko, Frank J., Winkler, Christoph, Currie, Peter D., Amaya, Enrique, Davis, Marcus C., Bronner, Marianne E., Mosimann, Christian, Carney, Tom J.

“…The development of paired appendages was a key innovation during evolution and facilitated the aquatic to terrestrial transition of vertebrates. Largely…”
Get full text

pIGLET : Safe harbor landing sites for reproducible and efficient transgenesis in zebrafish by Lalonde, Robert L, Wells, Harrison H, Kemmler, Cassie L, Nieuwenhuize, Susan, Lerma, Raymundo, Burger, Alexa, Mosimann, Christian

“…Standard zebrafish transgenesis involves random transgene integration with resource-intensive screening. While phiC31 integrase-based / recombination has…”
Get full text

Cover Image by Lalonde, Robert L., Kemmler, Cassie L., Riemslagh, Fréderike W., Aman, Andrew J., Kresoja‐Rakic, Jelena, Moran, Hannah R., Nieuwenhuize, Susan, Parichy, David M., Burger, Alexa, Mosimann, Christian

Get full text

Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1 R206H -Specific Human Cellular and Zebrafish Models by Wentworth, Kelly L, Lalonde, Robert L, Groppe, Jay C, Brewer, Niambi, Moody, Tania, Hansberry, Steven, Taylor, Kimberly E, Shore, Eileen M, Kaplan, Frederick S, Pignolo, Robert J, Yelick, Pamela C, Hsiao, Edward C

“…Bone morphogenetic protein (BMP) signaling is critical in skeletal development. Overactivation can trigger heterotopic ossification (HO) as in fibrodysplasia…”
Get full text