Search Results - "Lallemand, Benjamin"
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Sporopollenin Biosynthetic Enzymes Interact and Constitute a Metabolon Localized to the Endoplasmic Reticulum of Tapetum Cells
Published in Plant physiology (Bethesda) (01-06-2013)“…The sporopollenin polymer is the major constituent of exine, the outer pollen wall. Recently fatty acid derivatives have been shown to be the precursors of…”
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Amaryllidaceae Alkaloids Belonging to Different Structural Subgroups Display Activity against Apoptosis-Resistant Cancer Cells
Published in Journal of natural products (Washington, D.C.) (23-07-2010)“…Fifteen Amaryllidaceae alkaloids (1−15) were evaluated for their antiproliferative activities against six distinct cancer cell lines. Several of these natural…”
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Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines
Published in Bioorganic & medicinal chemistry letters (15-07-2011)“…A series of 25 selected oxyprenylated natural phenylpropanoids were synthesized, and their growth inhibitory activities were evaluated in vitro together with…”
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Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity
Published in International journal of oncology (01-08-2013)“…Ophiobolin A, a sesterterpenoid produced by plant pathogenic fungi, was purified from the culture extract of Drechslera gigantea and tested for its…”
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Analysis of TETRAKETIDE α-PYRONE REDUCTASE Function in Arabidopsis thaliana Reveals a Previously Unknown, but Conserved, Biochemical Pathway in Sporopollenin Monomer Biosynthesis
Published in The Plant cell (01-12-2010)“…The precise structure of the sporopollenin polymer that is the major constituent of exine, the outer pollen wall, remains poorly understood. Recently,…”
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LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B Encode Hydroxyalkyl α-Pyrone Synthases Required for Pollen Development and Sporopollenin Biosynthesis in Arabidopsis thaliana
Published in The Plant cell (01-12-2010)“…Plant type III polyketide synthases (PKSs) catalyze the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array…”
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Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas
Published in The FASEB journal (01-11-2010)“…Melanomas display poor response rates to adjuvant therapies because of their intrinsic resistance to proapoptotic stimuli. This study indicates that such…”
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Peak Compression Force Physics in Rugby Union Scrum
Published in Proceedings (01-06-2020)“…Scrums play a major role in Rugby Union games, and are historically known as a showdown between the two packs of opposing teams, composed of their eight…”
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N-(2-{3-[3,5-Bis(trifluoromethyl)phenyl]ureido}ethyl)-glycyrrhetinamide (6b): A Novel Anticancer Glycyrrhetinic Acid Derivative that Targets the Proteasome and Displays Anti-Kinase Activity
Published in Journal of medicinal chemistry (13-10-2011)“…18-β-Glycyrrhetinic acid (GA; 1) and many of its derivatives are cytotoxic in cancer cells. The current study aims to characterize the anticancer effects of 17…”
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Synthesis and plasma pharmacokinetics in CD-1 mice of a 18β-glycyrrhetinic acid derivative displaying anti-cancer activity
Published in Journal of pharmacy and pharmacology (01-03-2013)“…Objectives The plasma pharmacokinetic profile in CD‐1 mice of a novel 18β‐glycyrrhetinic acid (GA) derivative, which displays in vitro anti‐cancer activity,…”
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Evaluation of in vitro anticancer activity of sphaeropsidins A–C, fungal rearranged pimarane diterpenes, and semisynthetic derivatives
Published in Phytochemistry letters (01-12-2012)“…Sphearopsidins A (1), B and C, phytotoxins produced by Diplodia cupressi were tested together their semisynthetic derivatives for their in vitro anticancer…”
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Synthesis and plasma pharmacokinetics in CD-1 mice of a 18[beta]-glycyrrhetinic acid derivative displaying anti-cancer activity
Published in Journal of pharmacy and pharmacology (01-03-2013)“…Objectives The plasma pharmacokinetic profile in CD-1 mice of a novel 18[beta]-glycyrrhetinic acid (GA) derivative, which displays invitro anti-cancer…”
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Evaluation of the anticancer activities of two fungal polycyclic ethanones, alternethanoxins A and B, and two of their derivatives
Published in International journal of oncology (01-01-2011)“…Alternethanoxins A (1) and B (2) are fungal phytotoxins that are produced by Alternaria sonchi and have been recently characterized as new polycyclic…”
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In vitro anticancer activity, toxicity and structure–activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii
Published in Toxicology and applied pharmacology (01-07-2011)“…The in vitro anticancer activity and toxicity of phyllostictine A, a novel oxazatricycloalkenone recently isolated from a plant-pathogenic fungus (…”
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LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B Encode Hydroxyalkyl α-Pyrone Syntheses Required for Pollen Development and Sporopollenin Biosynthesis in Arabidopsis thaliana
Published in The Plant cell (01-12-2010)“…Plant type III polyketide synthases (PKSs) catalyze the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array…”
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Analysis of TETRAKETIDE [alpha]-PYRONE REDUCTASE Function in Arabidopsis thaliana Reveals a Previously Unknown, but Conserved, Biochemical Pathway in Sporopollenin Monomer Biosynthesis (C)(W)
Published in The Plant cell (01-12-2010)“…The precise structure of the sporopollenin polymer that is the major constituent of exine, the outer pollen wall, remains poorly understood. Recently,…”
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LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B Encode Hydroxyalkyl [alpha]-Pyrone Synthases Required for Pollen Development and Sporopollenin Biosynthesis in Arabidopsis thaliana (C)(W)(OA)
Published in The Plant cell (01-12-2010)“…Plant type III polyketide synthases (PKSs) catalyze the condensation of malonyl-CoA units with various CoA ester starter molecules to generate a diverse array…”
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Ceramide, cerebroside and triterpenoid saponin from the bark of aerial roots of Ficus elastica (Moraceae)
Published in Phytochemistry (Oxford) (01-11-2012)“…Three compounds, namely ficusamide (1), ficusoside (2) and elasticoside (3), together with nine known derivatives, were isolated from the bark of aerial roots…”
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