Search Results - "Laliberté, Alexandre"

Replication competent HIV-guided CRISPR screen identifies antiviral factors including targets of the accessory protein Nef by Prelli Bozzo, Caterina, Laliberté, Alexandre, De Luna, Aurora, Pastorio, Chiara, Regensburger, Kerstin, Krebs, Stefan, Graf, Alexander, Blum, Helmut, Volcic, Meta, Sparrer, Konstantin M. J., Kirchhoff, Frank

“…Innate antiviral factors are essential for effective defense against viral pathogens. However, the identity of major restriction mechanisms remains elusive…”
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Luciferase reporter assays to monitor interferon signaling modulation by SARS-CoV-2 proteins by Hirschenberger, Maximilian, Hayn, Manuel, Laliberté, Alexandre, Koepke, Lennart, Kirchhoff, Frank, Sparrer, Konstantin Maria Johannes

“…We present a protocol for analyzing the impact of SARS-CoV-2 proteins in interferon signaling using luciferase reporter assays. Here, the induction of defined…”
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Activation of the ILT7 receptor and plasmacytoid dendritic cell responses are governed by structurally-distinct BST2 determinants by Bego, Mariana G., Miguet, Nolwenn, Laliberté, Alexandre, Aschman, Nicolas, Gerard, Francine, Merakos, Angelique A., Weissenhorn, Winfried, Cohen, Éric A.

“…Type I interferons (IFN-I) are key innate immune effectors predominantly produced by activated plasmacytoid dendritic cells (pDCs). By modulating immune…”
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Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIVmac239 in rhesus macaques by Laliberté, Alexandre, Prelli Bozzo, Caterina, Stahl-Hennig, Christiane, Hunszinger, Victoria, Joas, Simone, Sauermann, Ulrike, Roshani, Berit, Klippert, Antonina, Daskalaki, Maria, Mätz-Rensing, Kerstin, Stolte-Leeb, Nicole, Tharp, Gregory K., Fuchs, Dietmar, Gupta, Prachi Mehrotra, Silvestri, Guido, Nelson, Sydney A., Parodi, Laura, Giavedoni, Luis, Bosinger, Steven E., Sparrer, Konstantin M.J., Kirchhoff, Frank

“…The accessory viral protein R (Vpr) is encoded by all primate lentiviruses. Vpr counteracts DNA repair pathways, modulates viral immune sensing, and induces…”
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Single-cell transcriptomics identifies prothymosin α restriction of HIV-1 in vivo by Geretz, Aviva, Ehrenberg, Philip K, Clifford, Robert J, Laliberté, Alexandre, Prelli Bozzo, Caterina, Eiser, Daina, Kundu, Gautam, Yum, Lauren K, Apps, Richard, Creegan, Matthew, Gunady, Mohamed, Shangguan, Shida, Sanders-Buell, Eric, Sacdalan, Carlo, Phanuphak, Nittaya, Tovanabutra, Sodsai, Russell, Ronnie M, Bibollet-Ruche, Frederic, Robb, Merlin L, Michael, Nelson L, Ake, Julie A, Vasan, Sandhya, Hsu, Denise C, Hahn, Beatrice H, Kirchhoff, Frank, Thomas, Rasmi

“…Host restriction factors play key roles in innate antiviral defense, but it remains poorly understood which of them restricts HIV-1 in vivo. Here, we used…”
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Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIV mac239 in rhesus macaques by Laliberté, Alexandre, Prelli Bozzo, Caterina, Stahl-Hennig, Christiane, Hunszinger, Victoria, Joas, Simone, Sauermann, Ulrike, Roshani, Berit, Klippert, Antonina, Daskalaki, Maria, Mätz-Rensing, Kerstin, Stolte-Leeb, Nicole, Tharp, Gregory K, Fuchs, Dietmar, Gupta, Prachi Mehrotra, Silvestri, Guido, Nelson, Sydney A, Parodi, Laura, Giavedoni, Luis, Bosinger, Steven E, Sparrer, Konstantin M J, Kirchhoff, Frank

“…The accessory viral protein R (Vpr) is encoded by all primate lentiviruses. Vpr counteracts DNA repair pathways, modulates viral immune sensing, and induces…”
Get full text