Search Results - "Lala, A K"

Increased exposure of hydrophobic surface in molten globule state of alpha-lactalbumin. Fluorescence and hydrophobic photolabeling studies by LALA, A. K, KAUL, P

“…The involvement of molten globule state as a distinct intermediate in the denaturation process in proteins is well documented. However, the structural…”
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Unfolding of diphtheria toxin. Identification of hydrophobic sites exposed on lowering of pH by photolabeling by D'Silva, P R, Lala, A K

“…We report here the use of a hydrophobic photoactivable reagent, 2-[3H]diazofluorene (DAF), to map the hydrophobic sites exposed when the pH is lowered in…”
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Intraoperative enteroscopy in obscure gastrointestinal hemorrhage by Lala, A K, Sitaram, V, Perakath, B, Ramakrishna, B S, Kurian, G, Khanduri, P

“…Forty three patients were diagnosed to have obscure gastrointestinal hemorrhage (OGH) between January 1987 and April 1996. Pre-operative diagnostic…”
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Hydrophobic photolabeling as a new method for structural characterization of molten globule and related protein folding intermediates by D'SILVA, PATRICK R., LALA, ANIL K.

“…Recent advances in attempts to unravel the protein folding mechanism have indicated the need to identify the folding intermediates. Despite their transient…”
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Photochemical labeling of membrane hydrophobic core of human erythrocytes using a new photoactivable reagent 2-[3H]diazofluorene by Pradhan, D, Lala, A K

“…Photoactivable reagents have been useful for studying the structural aspects of membrane hydrophobic core. We have reported earlier (Anjaneyulu, P.S.R., and…”
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Photolabeling of a pore-forming toxin with the hydrophobic probe 2- [3H]diazofluorene. Identification of membrane-inserted segments of Staphylococcus aureus alpha-toxin by Lala, A K, Raja, S M

“…The identification of membrane-inserted segments of pore-forming soluble proteins is crucial to understanding the action of these proteins at the molecular…”
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Conformation of Met5-enkephalin determined by high field PMR spectroscopy by Roques, B P, Garbay-Jaureguiberry, C, Oberlin, R, Anteunis, M, Lala, A K

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Organization of diphtheria toxin in membranes. A hydrophobic photolabeling study by D'Silva, P R, Lala, A K

“…Diphtheria toxin (DT) is a disulfide linked AB-toxin consisting of a catalytic domain (C), a membrane-inserting domain (T), and a receptor-binding domain (R)…”
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Topography of multiple spanning transmembrane proteins - a photochemical approach by Lala, A. K., Batliwala, H. F., Bhat, Sujata

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Sterol-phospholipid interaction in model membranes: role of C5-C6 double bond in cholesterol by Ranadive, G. N, Lala, Anil K

“…Several double-bond isomers of cholesterol where the normal C5-C6 double bond (delta 5) has been moved to different positions in the ring skeleton, i.e., delta…”
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Purification and characterization of a short insect toxin from the venom of the scorpion Buthus tamulus by Dhawan, Ritu, Joseph, Suresh, Sethi, Anurag, Lala, Anil K

“…A short chain peptide has been isolated from the venom of a red scorpion of Indian origin, Buthus tamulus. This peptide was purified using ion exchange and…”
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BTK-2, a new inhibitor of the Kv1.1 potassium channel purified from Indian scorpion Buthus tamulus by Dhawan, Ritu, Varshney, Anurag, Mathew, M.K, Lala, Anil K

“…A novel inhibitor of voltage-gated potassium channel was isolated and purified to homogeneity from the venom of the red scorpion Buthus tamulus. The primary…”
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Differential Effects of Cholesterol and Lanosterol on Artificial Membranes by Yeagle, Philip L., Martin, R. Bruce, Lala, Anil K., Lin, Hung-Kuang, Bloch, Konrad

“…The effects of cholesterol, 4,4-dimethylcholesterol, and lanosterol (4,4′,14α -trimethyl-Δ8,24-cholestadiene-3β -ol) on some properties of lecithin vesicles…”
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Localization and Environment of Tryptophans in Soluble and Membrane-Bound States of a Pore-Forming Toxin from Staphylococcus aureus by Raja, Srikumar M., Rawat, Satinder S., Chattopadhyay, Amitabha, Lala, Anil K.

“…The location and environment of tryptophans in the soluble and membrane-bound forms of Staphylococcus aureus α-toxin were monitored using intrinsic tryptophan…”
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The effect of the sterol oxygen function on the interaction with phospholipids by Demel, R A, Lala, A K, Kumari, S N, Van Deenen, L L

“…The effect of cholesteryl ethers (namely cholesteryl methyl ether, cholesteryl ethyl ether, cholesteryl n-propyl ether, cholesteryl isopropyl ether,…”
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Design, synthesis, and fluorescence studies of fluorenyl fatty acids as new depth-dependent fluorescent probes for membranes: getting over the looping-back problem by Lala, Anil K, Dixit, R. R, Koppaka, V, Patel, S

“…Fluorescent fatty acids have proved very useful in studying the membrane hydrophobic core. They readily partition into membranes or can be converted to…”
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Transverse location of new fluorene based depth dependent fluorescent probes in membranes--quenching studies with 9,10-dibromostearic acid by Lala, A K, Koppaka, V

“…Fluorescence quenching technique has been used to determine the transverse location of the fluorescent fluorenyl fatty acids in single bilayer vesicles…”
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On the role of the sterol hydroxyl group in membranes by Lala, A K, Buttke, T M, Bloch, K

“…The adequacy of sterol derivatives containing a blocked 3-hydroxyl group for sustaining the growth of two sterol auxotrophs has been investigated. Mycoplasma…”
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A new carbene based heterobifunctional reagent Photochemical crosslinking of aldolase by Mogre, R.M., Batliwala, H.F., Anjaneyulu, P.S.R., Lala, A.K.

“…The synthesis of a new photoactivatable heterobifunctional crosslinking reagent, the N-oxysuccinimide ester of 2-carboxy-9-diazofluorene, is described. The…”
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Identification and characterization of membrane-associated polypeptides in Torpedo nicotinic acetylcholine receptor-rich membranes by hydrophobic photolabeling by Blanton, Michael P., Lala, Anil K., Cohen, Jonathan B.

“…To identify membrane-associated polypeptides present in Torpedo nicotinic acetylcholine receptor (AChR)-rich membranes, we used hydrophobic photolabeling with…”
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