Search Results - "Lal Gupta, Chhedi"
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Platforms for elucidating antibiotic resistance in single genomes and complex metagenomes
Published in Environment international (01-05-2020)“…•We review bioinformatics platforms to explore ARG in high-throughput sequencing data.•We discuss the strength and weakness of available tools for different…”
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Microbiome in sickle cell disease: Pathophysiology and therapeutic insights
Published in British journal of haematology (01-10-2024)“…Sickle cell disease (SCD) is a complex genetic blood disorder characterized by abnormal haemoglobin, resulting in sickle-shaped red blood cells. While…”
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Hidden Resistome: Enrichment Reveals the Presence of Clinically Relevant Antibiotic Resistance Determinants in Treated Wastewater-Irrigated Soils
Published in Environmental science & technology (18-05-2021)“…Treated-wastewater (TW) irrigation transfers antibiotic-resistant bacteria (ARB) to soil, but persistence of these bacteria is generally low due to resilience…”
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Impelling TLR9: Road to perspective vaccine for visceral leishmaniasis
Published in Drug development research (01-04-2022)“…Recent trends in immunotherapy have shown enthusiasm in exploring Toll‐like receptors (TLRs) for designing therapeutical interventions against numerous deadly…”
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Corrigendum: Comparative genomics of Bacillus cereus sensu lato spp. biocontrol strains in correlation to in-vitro phenotypes and plant pathogen antagonistic capacity
Published in Frontiers in microbiology (23-10-2023)“…[This corrects the article DOI: 10.3389/fmicb.2023.996287.]…”
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Comparative genomics of Bacillus cereus sensu lato spp. biocontrol strains in correlation to in-vitro phenotypes and plant pathogen antagonistic capacity
Published in Frontiers in microbiology (09-02-2023)“…(Bcsl) strains are widely explored due to their capacity to antagonize a broad range of plant pathogens. These include sp. UW85, whose antagonistic capacity is…”
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Assessment of Diazotrophic Proteobacteria in Sugarcane Rhizosphere When Intercropped With Legumes (Peanut and Soybean) in the Field
Published in Frontiers in microbiology (31-07-2020)“…Several factors influenced the sugarcane production, and among them, higher use of nitrogen and depletion of soil nutrient constitutes a significant concern in…”
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Longitudinal study on the effects of growth-promoting and therapeutic antibiotics on the dynamics of chicken cloacal and litter microbiomes and resistomes
Published in Microbiome (28-08-2021)“…Therapeutic and growth-promoting antibiotics are frequently used in broiler production. Indirect evidence indicates that these practices are linked to the…”
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Microglial TLR9: Plausible Novel Target for Therapeutic Regime Against Glioblastoma Multiforme
Published in Cellular and molecular neurobiology (01-10-2021)Get full text
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Functional attributes of evolutionary conserved Arg45 of Wolbachia (Brugia malayi) translation initiation factor-1
Published in Future microbiology (01-01-2016)“…Wolbachia is a promising antifilarial chemotherapeutic target. Translation initiation factor-1 (Tl IF-1) is an essential factor in prokaryotes. Functional…”
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Spatial and temporal dynamics of microbiomes and resistomes in broiler litter stockpiles
Published in Computational and structural biotechnology journal (01-01-2021)“…[Display omitted] Farmers apply broiler chicken litter to soils to enrich organic matter and provide crops with nutrients, following varying periods of…”
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Wolbachia transcription elongation factor "Wol GreA" interacts with α2ββ'σ subunits of RNA polymerase through its dimeric C-terminal domain
Published in PLoS neglected tropical diseases (01-06-2014)“…Wolbachia, an endosymbiont of filarial nematode, is considered a promising target for therapy against lymphatic filariasis. Transcription elongation factor…”
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Microglial TLR9: Plausible Novel Target for Therapeutic Regime Against Glioblastoma Multiforme
Published in Cellular and molecular neurobiology (01-10-2021)“…An understanding of pattern recognition receptors (PRRs) and immunomodulatory approach based on activation of these receptors has provided insights critical…”
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Repolarization of glioblastoma macrophage cells using non-agonistic Dectin-1 ligand encapsulating TLR-9 agonist: plausible role in regenerative medicine against brain tumor
Published in International journal of neuroscience (03-06-2021)“…Glioblastoma multiforme (GBM) is the most severe forms of brain cancer, eventually becoming the leading cause of brain cancer-related death worldwide. Owing to…”
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Leishmanial CpG DNA nanovesicles: A propitious prophylactic approach against visceral leishmaniasis
Published in International immunopharmacology (01-01-2021)“…Schematic illustration of study plan undertaken to evaluate prophylactic efficacy of novel TLR9 agonist recognized from L. donovani genome. Schizophyllan; a…”
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Molecular characterization of recombinant arginase of Leishmania donovani
Published in Protein expression and purification (01-07-2019)“…Arginase catalyzes the first committed step in the biosynthesis of polyamines that enable cell growth and hence potential drug target for the treatment of…”
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Pharmacophore-based virtual screening approach for identification of potent natural modulatory compounds of human Toll-like receptor 7
Published in Journal of biomolecular structure & dynamics (12-12-2019)“…Toll-like receptor 7 (TLR7) is a transmembrane glycoprotein playing very crucial role in the signaling pathways involved in innate immunity and has been…”
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PAR 1&2 driven placenta EVT invasion act via LRP5/6 as coreceptors
Published in The FASEB journal (01-12-2020)“…While the involvement of protease-activated receptors (PARs) in the physiological regulation of human placenta development, as in tumor biology, is recognized,…”
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Antiproliferative activity and mode of action analysis of novel amino and amido substituted phenantrene and naphtho[2,1-b]thiophene derivatives
Published in European journal of medicinal chemistry (01-01-2020)“…Herein we present and describe the design and synthesis of novel phenantrene derivatives substituted with either amino or amido side chains and their…”
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PAR1&2 driven placenta EVT invasion act via LRP5/6 as coreceptors
Published in The FASEB journal (01-12-2020)“…While the involvement of protease‐activated receptors (PARs) in the physiological regulation of human placenta development, as in tumor biology, is recognized,…”
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