Search Results - "Lakshmikanth, T"
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Studies on the sequential pathology of Kyasanur Forest Disease (KFD) in Mouse brain: KFD virus induces apoptosis of neurons in cerebrum and hippocampus
Published in PloS one (01-03-2024)“…The sequential pathology of Kyasanur forest disease (KFD) in mouse brain was assessed in this study. Kyasanur forest disease virus (KFDV) strain P9605 used in…”
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Journal Article -
2
Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice
Published in Diabetologia (01-04-2013)“…Aims/hypothesis Enterovirus (e.g. Coxsackie B virus serotypes [CVBs]) infections may be associated with development of type 1 diabetes. Studies conducted in…”
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3
Human Immune System Variation during 1 Year
Published in Cell reports (Cambridge) (21-07-2020)“…The human immune system varies extensively between individuals, but variation within individuals over time has not been well characterized. Systems-level…”
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4
Enhanced Edge Computing Model by using Data Combs for Big Data in Metaverse
Published in 2023 International Conference on Intelligent Data Communication Technologies and Internet of Things (IDCIoT) (05-01-2023)“…The Metaverse is a huge project undertaken by Facebook in order to bring the world closer together and help people live out their dreams. Even handicapped can…”
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Conference Proceeding -
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Building Robust FinTech Applications and Reducing Strain on Strategic Data Centers using the LoTus Model
Published in 2023 7th International Conference on Intelligent Computing and Control Systems (ICICCS) (17-05-2023)“…Agile is a well-known project management approach that has been used for many years. It places a strong emphasis on client satisfaction, adaptability, and…”
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Conference Proceeding -
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Enhanced Automated Oxygen Level controller for COVID Patient By Using Internet of Things (IoT)
Published in 2022 6th International Conference on Electronics, Communication and Aerospace Technology (01-12-2022)“…The Internet of Things (IoT) shall be merged firmly and interact with a higher number of altered embedded sensor networks. It provides open access for the…”
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Conference Proceeding -
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Stereotypic Immune System Development in Newborn Children
Published in Cell (23-08-2018)“…Epidemiological data suggest that early life exposures are key determinants of immune-mediated disease later in life. Young children are also particularly…”
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Journal Article -
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The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19
Published in Cell (12-11-2020)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is typically very mild and often asymptomatic in children. A complication is the rare…”
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A genome-wide transcriptomic analysis of protein-coding genes in human blood cells
Published in Science (American Association for the Advancement of Science) (20-12-2019)“…Blood is the predominant source for molecular analyses in humans, both in clinical and research settings. It is the target for many therapeutic strategies,…”
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10
Bifidobacteria-mediated immune system imprinting early in life
Published in Cell (22-07-2021)“…Immune-microbe interactions early in life influence the risk of allergies, asthma, and other inflammatory diseases. Breastfeeding guides healthier…”
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Preliminary study of micromechanical stress delivery for cell biology studies
Published in Microelectronic engineering (01-05-2007)“…Cell programs as growth and differentiation are determined by the chemical and physical characteristics of the extra cellular matrix (ECM). Changes in the…”
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Journal Article Conference Proceeding -
12
The repertoire of maternal anti-viral antibodies in human newborns
Published in Nature medicine (01-04-2019)“…All circulating immunoglobulin G (IgG) antibodies in human newborns are of maternal origin 1 and transferred across the placenta to provide passive immunity…”
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Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation
Published in Cell metabolism (06-02-2018)“…The role of tryptophan-kynurenine metabolism in psychiatric disease is well established, but remains less explored in peripheral tissues. Exercise training…”
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14
Studies on the sequential pathology of Kyasanur Forest Disease
Published in PloS one (01-03-2024)“…The sequential pathology of Kyasanur forest disease (KFD) in mouse brain was assessed in this study. Kyasanur forest disease virus (KFDV) strain P9605 used in…”
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Journal Article -
15
Integration of molecular profiles in a longitudinal wellness profiling cohort
Published in Nature communications (2020)“…An important aspect of precision medicine is to probe the stability in molecular profiles among healthy individuals over time. Here, we sample a longitudinal…”
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Longitudinal analyses of development of the immune system during the first five years of life in relation to lifestyle
Published in Allergy (Copenhagen) (01-05-2022)“…Background Changes in immune cell composition during the immunological window within the first years after birth are not fully understood, especially the…”
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Journal Article -
17
The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells
Published in Blood (12-03-2009)“…Natural killer (NK) cells express inhibitory receptors for major histocompatibility complex (MHC) class I. If self-MHC is down-regulated or absent, lack of…”
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Normalized Interferon Signatures and Clinical Improvements by IFNAR1 Blocking Antibody (Anifrolumab) in Patients with Type I Interferonopathies
Published in Journal of clinical immunology (01-12-2025)“…Purpose A causal role of type-I interferons (IFN-I) in autoinflammatory type-I interferonopathies such as SAVI (STING–associated vasculopathy with onset in…”
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Journal Article -
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Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19
Published in Cell reports. Medicine (25-08-2020)“…Severe disease of SARS-CoV-2 is characterized by vigorous inflammatory responses in the lung, often with a sudden onset after 5–7 days of stable disease…”
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Journal Article -
20
Automated Cell Processing for Mass Cytometry Experiments
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Mass cytometry is a powerful technology for high-dimensional single-cell measurements in millions of individual cells. Antibodies and other detection probes…”
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