Search Results - "Lakomek, Max"
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Hyperkalemia complicating propranolol treatment of an infantile hemangioma
Published in Pediatrics (Evanston) (01-12-2010)“…Propranolol treatment was recently reported to be successful for the management of severe infantile hemangioma. Known adverse effects of propranolol treatment…”
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2
Poor Outcome for Children and Adolescents With Progressive Disease or Relapse of Lymphoblastic Lymphoma: A Report From the Berlin-Frankfurt-Muenster Group
Published in Journal of clinical oncology (10-07-2009)“…Little is known about the outcome of pediatric patients with lymphoblastic lymphoma (LBL) who suffer from progressive disease or relapse. We analyzed the…”
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3
Potential involvement of F₀F₁-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines
Published in Apoptosis (London) (01-07-2010)“…Erucylphosphohomocholine (ErPC3, Erufosine™) was reported previously to induce apoptosis in otherwise highly apoptosis-resistant malignant glioma cell lines…”
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4
Monitoring Proteins Using In Vivo Near-Infrared Time-Domain Optical Imaging after 2-O-Hexyldiglycerol-Mediated Transfer to the Brain
Published in Molecular imaging and biology (01-04-2011)“…Purpose The aim of the present study was to gain insight into the penetration, biodistribution, and fate of globulins in the brain after 2- O…”
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5
Low occurrence of familial neuroblastomas and ganglioneuromas in five consecutive GPOH neuroblastoma treatment studies
Published in European journal of cancer (1990) (01-12-2004)“…Familial neuroblastoma is of special interest in view of the oncogenesis of this tumour with its early manifestation in childhood. The inheritance seems to…”
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6
Cranial irradiation of female rats causes dose-dependent and age-dependent activation or inhibition of pubertal development
Published in Pediatric research (01-05-2000)“…Cranial irradiation in prepubertal children with leukemia or brain tumors can lead to precocious or in high doses to late puberty. To unravel the underlying…”
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Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine
Published in Cellular oncology : the official journal of the International Society for Cellular Oncology (2008)“…We have previously shown that the anti-neoplastic agent erucylphosphohomocholine (ErPC3) requires the mitochondrial 18 kDa Translocator protein (TSPO),…”
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Cisplatin nephrotoxicity in children after continuous 72-h and 3×1-h infusions
Published in Pediatric nephrology (Berlin, West) (01-07-2001)“…Little is known about the association be- tween the rate of cisplatin administration and the severity of cisplatin-induced renal damage in children. The…”
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9
The 18 kDa translocator protein influences angiogenesis, as well as aggressiveness, adhesion, migration, and proliferation of glioblastoma cells
Published in Pharmacogenetics and genomics (01-07-2012)“…BACKGROUNDIt is known that the mitochondrial 18 kDa translocator protein (TSPO) is present in almost all peripheral tissues and also in glial cells in the…”
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10
Abstract 1539: Impact of glioma cell gene expression due to semaphorin expression
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Malignant brain tumours, like the Glioblastoma multiforme, belong to the most frequent tumours encountered in childhood. Unfortunately, even with optimal…”
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Effects of 18-kDa translocator protein knockdown on gene expression of glutamate receptors, transporters, and metabolism, and on cell viability affected by glutamate
Published in Pharmacogenetics and genomics (01-08-2012)“…OBJECTIVEPreviously, several important roles for glutamate have been described for the biology of primary brain tumors. For example, glutamate has been…”
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12
Favourable outcome of patients with childhood acute promyelocytic leukaemia after treatment with reduced cumulative anthracycline doses
Published in British journal of haematology (01-05-2010)“…Summary Acute promyelocytic leukaemia (APL) treatment often includes high cumulative doses of anthracyclines, which can cause long‐term cardiotoxicity. Here,…”
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13
Tumor localization of an anti-TGF-β antibody and its effects on gliomas
Published in International journal of oncology (01-01-2011)“…Even with current standard-of-care therapies, the prognosis for patients with malignant gliomas is very poor and several new treatment modalities for…”
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14
Ontogeny of the GNRH-, glutaminase- and glutamate decarboxylase-gene expression in the hypothalamus of female rats
Published in Brain research. Developmental brain research (10-09-1998)“…Amino acid neurotransmitters like γ-aminobutyric acid (GABA) and glutamate (GLU) are involved in the regulation of hypothalamic gonadotropin releasing hormone…”
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Abstract 5229: In vivo bioluminescence imaging of intracranially implanted glioma cells and opening of the blood-brain-barrier in mice
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) occur more frequently than other types of primary central nervous system tumors. Their…”
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Epidemiological investigation on chronic copper toxicity to children exposed via the public drinking water supply
Published in The Science of the total environment (20-01-2003)“…Copper in drinking water has been associated with Non-Indian Childhood Cirrhosis (NICC), a form of early childhood liver cirrhosis. This epidemiological study…”
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Alkylglycerol opening of the blood–brain barrier to small and large fluorescence markers in normal and C6 glioma‐bearing rats and isolated rat brain capillaries
Published in British journal of pharmacology (01-12-2003)“…The blood–brain barrier (BBB) represents the major impediment to successful delivery of therapeutic agents to target tissue within the central nervous system…”
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The Peripheral-Type Benzodiazepine Receptor and Tumorigenicity: Isoquinoline Binding Protein (IBP) Antisense Knockdown in the C6 Glioma Cell Line
Published in Biochemistry (Easton) (26-07-2005)“…Peripheral-type benzodiazepine receptors (PBR) are constituted by three protein components, the isoquinoline binding protein (IBP), the voltage-dependent anion…”
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Antibody levels against tetanus and diphtheria after polychemotherapy for childhood sarcoma: A report from the Late Effects Surveillance System
Published in Vaccine (11-02-2011)“…Abstract Background It is known that antineoplastic treatment may induce secondary immunodeficiency, but studies after childhood sarcoma are rare. Since 1998,…”
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Potential involvement of F0F1-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines: A mechanism for induction of apoptosis via the 18 kDa mitochondrial translocator protein
Published in Apoptosis (London) (01-07-2010)“…Erucylphosphohomocholine (ErPC3, Erufosine™) was reported previously to induce apoptosis in otherwise highly apoptosis-resistant malignant glioma cell lines…”
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