Search Results - "Lake, Jordan"
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The Fat of the Matter: Obesity and Visceral Adiposity in Treated HIV Infection
Published in Current HIV/AIDS reports (01-12-2017)“…Purpose of Review The aim of this review is to summarize knowledge of the prevalence, relevant physiology, and consequences of obesity and visceral adiposity…”
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2
Impact of Integrase inhibitors and tenofovir alafenamide on weight gain in people with HIV
Published in Current opinion in HIV & AIDS (01-05-2021)“…Obesity is increasing in people with HIV (PWH). This review aims to summarise the recent evidence investigating the associations between the use of integrase…”
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Weight Gain Following Initiation of Antiretroviral Therapy: Risk Factors in Randomized Comparative Clinical Trials
Published in Clinical infectious diseases (12-09-2020)“…Abstract Background Initiation of antiretroviral therapy (ART) often leads to weight gain. While some of this weight gain may be an appropriate…”
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Metabolic disease in HIV infection
Published in The Lancet infectious diseases (01-11-2013)“…Summary The treatment of metabolic disease is becoming an increasingly important component of the long-term management of patients with well controlled HIV on…”
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Risk Factors for Weight Gain Following Switch to Integrase Inhibitor–Based Antiretroviral Therapy
Published in Clinical infectious diseases (03-12-2020)“…Abstract Background Treatment initiation with integrase strand transfer inhibitors (INSTIs) has been associated with excess weight gain. Whether similar gains…”
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HIV and antiretroviral therapy-related fat alterations
Published in Nature reviews. Disease primers (18-06-2020)“…Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss (lipoatrophy), with or without central fat accumulation (lipohypertrophy), was…”
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Obesity following ART initiation is common and influenced by both traditional and HIV-/ART-specific risk factors
Published in Journal of antimicrobial chemotherapy (01-08-2018)“…Obesity rates are increasing among HIV-infected individuals, but risk factors for obesity development on ART remain unclear. In a cohort of HIV-infected adults…”
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Weight Change Following Antiretroviral Therapy Switch in People With Viral Suppression: Pooled Data from Randomized Clinical Trials
Published in Clinical infectious diseases (20-10-2021)“…We sought to identify factors associated with weight gain in randomized clinical trials of antiretroviral therapy (ART) switch. We explored the effects of…”
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Optimizing HIV prevention and care for transgender adults
Published in AIDS (London) (01-03-2019)“…Transgender women have recently been acknowledged as a unique and important risk group in HIV research and care. Although transgender men also face specific…”
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Dolutegravir/abacavir/lamivudine versus current ART in virally suppressed patients (STRIIVING): a 48-week, randomized, non-inferiority, open-label, Phase IIIb study
Published in Antiviral therapy (01-01-2017)“…Simplified dosing regimens are important for patients who face challenges in adhering to HIV-1 therapy. We investigated the safety and virological efficacy of…”
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Expert Panel Review on Nonalcoholic Fatty Liver Disease in Persons With Human Immunodeficiency Virus
Published in Clinical gastroenterology and hepatology (01-02-2022)“…Nonalcoholic fatty liver disease (NAFLD) affects 25% of adults in the general population and is a disease spectrum ranging from steatosis to nonalcoholic…”
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Non-alcoholic fatty liver disease is not associated with impairment in health-related quality of life in virally suppressed persons with human immune deficiency virus
Published in PloS one (10-02-2023)“…Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in persons with HIV (PWH) (HIV-NAFLD). It is unknown if HIV-NAFLD is associated with…”
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Weight Gain After Antiretroviral Therapy Initiation and Subsequent Risk of Metabolic and Cardiovascular Disease
Published in Clinical infectious diseases (17-02-2024)“…Weight gain following initiation of antiretroviral therapy (ART) is common. We assessed the impact of changes in weight in the year following ART initiation…”
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Practical Review of Recognition and Management of Obesity and Lipohypertrophy in Human Immunodeficiency Virus Infection
Published in Clinical infectious diseases (15-05-2017)“…Background. Obesity and lipohypertrophy are common in treated human immunodeficiency virus (HIV) infection and contribute to morbidity and mortality among…”
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HIV Infection Is Associated with Increased Fatty Infiltration of the Thigh Muscle with Aging Independent of Fat Distribution
Published in PloS one (06-01-2017)“…Lower muscle density on computed tomography (CT) provides a measure of fatty infiltration of muscle, an aspect of muscle quality that has been associated with…”
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Risk of Incident Diabetes Mellitus, Weight Gain, and Their Relationships With Integrase Inhibitor-Based Initial Antiretroviral Therapy Among Persons With Human Immunodeficiency Virus in the United States and Canada
Published in Clinical infectious diseases (05-10-2021)“…Integrase strand transfer inhibitor (INSTI)-based combination antiretroviral therapy (cART) is associated with greater weight gain among persons with human…”
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Adipose Tissue Dysfunction and Energy Balance Paradigms in People Living With HIV
Published in Endocrine reviews (04-03-2024)“…Abstract Over the past 4 decades, the clinical care of people living with HIV (PLWH) evolved from treatment of acute opportunistic infections to the management…”
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Abdominal obesity, sarcopenia, and osteoporosis are associated with frailty in men living with and without HIV
Published in AIDS (London) (19-06-2018)“…OBJECTIVE:The relationships between frailty and body composition in older adults with HIV infection are poorly understood. We sought to describe associations…”
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Burden of fatty liver and hepatic fibrosis in persons with HIV: A diverse cross-sectional US multicenter study
Published in Hepatology (Baltimore, Md.) (01-08-2023)“…The current prevalence of fatty liver disease (FLD) due to alcohol-associated (AFLD) and nonalcoholic (NAFLD) origins in US persons with HIV (PWH) is not well…”
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Progressive increases in fat mass occur in adults living with HIV on antiretroviral therapy, but patterns differ by sex and anatomic depot
Published in Journal of antimicrobial chemotherapy (01-04-2019)“…Abstract Objectives Although weight gain on ART is common, the long-term trajectory of and factors affecting increases in fat mass in people living with HIV…”
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