Search Results - "Lake, G."

Pathogen Distribution and Antimicrobial Resistance Among Pediatric Healthcare-Associated Infections Reported to the National Healthcare Safety Network, 2011-2014 by Lake, Jason G, Weiner, Lindsey M, Milstone, Aaron M, Saiman, Lisa, Magill, Shelley S, See, Isaac

“…OBJECTIVE To describe pathogen distribution and antimicrobial resistance patterns for healthcare-associated infections (HAIs) reported to the National…”
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Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) by Yamada, Tomoya, Cohen, Samuel M., Lake, Brian G.

“…Many nongenotoxic chemicals have been shown to produce liver tumors in mice and/or rats by a mode of action (MOA) involving activation of the constitutive…”
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Thin, thick and dark discs in ΛCDM by Read, J. I., Lake, G., Agertz, O., Debattista, Victor P.

“…In a Λ cold dark matter (ΛCDM) cosmology, the Milky Way accretes satellites into the stellar disc. We use cosmological simulations to assess the frequency of…”
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Constraining the Milky Way halo shape using thin streams by Lux, H., Read, J. I., Lake, G., Johnston, K. V.

“…Tidal streams are a powerful probe of the Milky Way (MW) potential shape. In this paper, we introduce a simple test-particle method to fit stream data, using a…”
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Induction of drug metabolism: Species differences and toxicological relevance by Graham, Mark J, Lake, Brian G

“…Abstract A large number of drugs and other chemicals have been shown to induce hepatic microsomal cytochrome P450 (CYP) forms in experimental animals and…”
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Determining orbits for the Milky Way's dwarfs by Lux, H., Read, J. I., Lake, G.

“…We calculate orbits for the Milky Way dwarf galaxies with proper motions, and compare these to subhalo orbits in a high-resolution cosmological simulation. We…”
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Pituitary Adenomas: An Overview by Lake, Marcy G., DO, Krook, Linda S., MD, Cruz, Samya V., MD

“…Prolactinomas and nonfunctioning adenomas are the most common types of pituitary adenomas. Patients with pituitary adenomas may present initially with symptoms…”
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Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans by Mallick, Pankajini, Moreau, Marjory, Song, Gina, Efremenko, Alina Y, Pendse, Salil N, Creek, Moire R, Osimitz, Thomas G, Hines, Ronald N, Hinderliter, Paul, Clewell, Harvey J, Lake, Brian G, Yoon, Miyoung

“…Abstract To address concerns around age-related sensitivity to pyrethroids, a life-stage physiologically based pharmacokinetic (PBPK) model, supported by in…”
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Making a difference in the real world. User-centred impact evaluation of an eight-country, community-based early childhood programme by Lake, G., Urban, M., Giblin, F., French, G., Farrell, T.

“…This paper presents a unique approach to the Impact Evaluation of a project that focused on low-threshold intergenerational play-based interactions in order to…”
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A Stable Finite-Difference Scheme for Population Growth and Diffusion on a Map by Petersen, W P, Callegari, S, Lake, G R, Tkachenko, N, Weissmann, J D, Zollikofer, Ch P E

“…We describe a general Godunov-type splitting for numerical simulations of the Fisher-Kolmogorov-Petrovski-Piskunov growth and diffusion equation on a world map…”
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Globular cluster formation in the Virgo cluster by Moran, C. Corbett, Teyssier, R., Lake, G.

“…Metal-poor globular clusters (MPGCs) are a unique probe of the early universe, in particular the reionization era. A popular hypothesis is that the observed…”
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Cold collapse and the core catastrophe by Moore, B., Quinn, T., Governato, F., Stadel, J., Lake, G.

“…We show that a universe dominated by cold dark matter fails to reproduce the rotation curves of dark matter dominated galaxies, one of the key problems that it…”
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A dark matter disc in three cosmological simulations of Milky Way mass galaxies by Read, J. I., Mayer, L., Brooks, A. M., Governato, F., Lake, G.

“…Making robust predictions for the phase-space distribution of dark matter at the solar neighbourhood is vital for dark matter direct-detection experiments. To…”
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Density Profiles and Substructure of Dark Matter Halos: Converging Results at Ultra-High Numerical Resolution by Ghigna, S, Moore, B, Governato, F, Lake, G, Quinn, T, Stadel, J

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Involvement of Peroxisome Proliferator-Activated Receptor-Alpha in Liver Tumor Production by Permethrin in the Female Mouse by Kondo, Miwa, Miyata, Kaori, Nagahori, Hirohisa, Sumida, Kayo, Osimitz, Thomas G, Cohen, Samuel M, Lake, Brian G, Yamada, Tomoya

“…Abstract The nongenotoxic pyrethroid insecticide permethrin produced hepatocellular tumors in CD-1 mice but not in Wistar rats. Recently, based on findings of…”
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Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes by Haines, Corinne, Elcombe, Barbara M., Chatham, Lynsey R., Vardy, Audrey, Higgins, Larry G., Elcombe, Clifford R., Lake, Brian G.

“…Phenobarbital (PB), a constitutive androstane receptor (CAR) activator, produces liver tumours in rodents by a mitogenic mode of action involving CAR…”
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Interpersonal Firearm Injury and Death in Portland, Oregon: 2018 Through 2021 by Lake, Marcy G., Baker-Robinson, William, Harris, Jeffrey R., Rowhani-Rahbar, Ali, Carlson, Kathleen F., Bezruchka, Stephen

“…The annual number of firearm injuries in Portland, Oregon has been higher in the years since 2020 than in any prior year in the city’s history. This…”
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B cell activating factor (BAFF) in the natural history of chronic hepatitis C virus liver disease and mixed cryoglobulinaemia by Lake‐Bakaar, G., Jacobson, I., Talal, A.

“…Summary B cell activating factor (BAFF) plays a crucial role in the process of development, maturation and activation of B lymphocytes. Chronic hepatitis C…”
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Resolving the Structure of Cold Dark Matter Halos by Moore, B, Governato, F, Quinn, T, Stadel, J, Lake, G

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Editor's Highlight: Mode of Action Analysis for Rat Hepatocellular Tumors Produced by the Synthetic Pyrethroid Momfluorothrin: Evidence for Activation of the Constitutive Androstane Receptor and Mitogenicity in Rat Hepatocytes by Okuda, Yu, Kushida, Masahiko, Sumida, Kayo, Nagahori, Hirohisa, Nakamura, Yoshimasa, Higuchi, Hashihiro, Kawamura, Satoshi, Lake, Brian G, Cohen, Samuel M, Yamada, Tomoya

“…High dietary levels of momfluorothrin, a nongenotoxic synthetic pyrethroid, induced hepatocellular tumors in male and female Wistar rats in a 2-year bioassay…”
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