Search Results - "Lake, Camille"

Sequence similarity between SARS-CoV-2 nucleocapsid and multiple sclerosis-associated proteins provides insight into viral neuropathogenesis following infection by Lake, Camille M., Breen, Joseph J.

“…The novel coronavirus SARS-CoV-2 continues to cause death and disease throughout the world, underscoring the necessity of understanding the virus and host…”
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Restimulation-Induced Cell Death (RICD): Methods for Modeling, Investigating, and Quantifying RICD Sensitivity in Primary Human T Cells via Flow Cytometric Analysis by Pohida, Katherine, Lake, Camille M, Yee, Debra, Snow, Andrew L

“…When the body mounts an immune response against a foreign pathogen, the adaptive arm of the immune system relies upon clonal expansion of antigen-specific T…”
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TIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8+ T cells in conjunction with CEACAM1 by Lake, Camille M., Voss, Kelsey, Bauman, Bradly M., Pohida, Katherine, Jiang, Timothy, Dveksler, Gabriela, Snow, Andrew L.

“…Immune homeostasis depends upon effective clearance of pathogens while simultaneously preventing autoimmunity and immunopathology in the host…”
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Seroprevalence of Baylisascaris procyonis Infection among Humans, Santa Barbara County, California, USA, 2014-2016 by Weinstein, Sara B, Lake, Camille M, Chastain, Holly M, Fisk, David, Handali, Sukwan, Kahn, Philip L, Montgomery, Susan P, Wilkins, Patricia P, Kuris, Armand M, Lafferty, Kevin D

“…Baylisascaris procyonis (raccoon roundworm) infection is common in raccoons and can cause devastating pathology in other animals, including humans. Limited…”
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Using publicly available, interactive epidemiological dashboards: an innovative approach to sharing data from the Rakai Community Cohort Study by Footer, Kevin, Lake, Camille M, Porter, Joshua R, Ha, Grace K, Ahmed, Tanvir, Glogowski, Alex, Ndyanabo, Anthony, Grabowski, M Kate, Chang, Larry W, Ssekasanvu, Joseph, Kagaayi, Joseph, Serwadda, David M, Mckina, Jackie, Whalen, Christopher, Ssentongo, Lloyd, Nsimbi, Ivan, Kakeeto, Benedicto, Kigozi, Godfrey, Ssekubugu, Robert, Lutalo, Tom, Wawer, Maria J, Gray, Ronald H, Reynolds, Steven J, Rosenthal, Alex, Quinn, Thomas C, Tartakovsky, Michael

“…Public sharing of de-identified biomedical data promotes collaboration between researchers and accelerates the development of disease prevention and treatment…”
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Sequence similarity between SARS-CoV-2 Nucleocapsid and CNS proteins provides mechanistic insight into viral neuropathogenesis following infection by Lake, Camille, Breen, Joseph

“…Abstract The novel coronavirus SARS-CoV-2 emerged in 2019 and continues to cause death and disease throughout the world. To date, there have been 272 million…”
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PD-1 protects expanding human T cells from premature restimulation-induced cell death by Lee, Katherine, Elster, Sara, Lake, Camille M, Snow, Andrew L

“…Abstract Programmed cell death-1 (PD-1) is a co-inhibitory protein that dampens TCR/CD28 signaling in part by recruiting the phosphatase SHP2 to the…”
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TIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8+ T cells in conjunction with CEACAM1 by Lake, Camille, Voss, Kelsey, Bauman, Bradly M., Pohida, Katherine, Jiang, Timothy, Dveksler, Gabriela, Snow, Andrew L.

“…Abstract Immune homeostasis depends upon effective clearance of pathogens while simultaneously preventing immunopathology in the host. Restimulation-induced…”
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TIM-3-dependent regulation of restimulation-induced cell death sensitivity flips changes in early versus late-stage human effector T cells by Lake, Camille, Jiang, Timothy, Bauman, Bradley, Voss, Kelsey, Snow, Andrew L

“…Abstract In healthy individuals, the balance between immune-mediated pathogen clearance and tissue damage is tightly regulated through multiple processes. One…”
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URBAn Native Elders: Risk and Protective Factors for Alzheimer’s Disease and Related Dementias ‐ Overview and Methods by Nelson, Lonnie A, Mednansky, Sage W., Pham‐Lake, Camille, Bryne, Charlotte, Jones, Jacob, Valenzuela, Yenny Gabriela, Rivas, Rhiannon, Cuellar‐Rocha, Priscilla, West, Cynthia, Lee, Sunny T., Ali, Tauqeer, Collier, Ann, Mortenson, Ryan, Suchy‐Dicey, Astrid M, Muller, Clemma, Buchwald, Dedra

“…Background Over 86% of American Indian and Alaska Native elders live in urban metropolitan areas, yet the extant epidemiological data on cognition and aging in…”
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Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease by Ozen, Ahmet, Kasap, Nurhan, Vujkovic-Cvijin, Ivan, Apps, Richard, Cheung, Foo, Karakoc-Aydiner, Elif, Akkelle, Bilge, Sari, Sinan, Tutar, Engin, Ozcay, Figen, Uygun, Dilara Kocacik, Islek, Ali, Akgun, Gamze, Selcuk, Merve, Sezer, Oya Balci, Zhang, Yu, Kutluk, Gunsel, Topal, Erdem, Sayar, Ersin, Celikel, Cigdem, Houwen, Roderick H. J., Bingol, Aysen, Ogulur, Ismail, Eltan, Sevgi Bilgic, Snow, Andrew L., Lake, Camille, Fantoni, Giovanna, Alba, Camille, Sellers, Brian, Chauvin, Samuel D., Dalgard, Clifton L., Harari, Olivier, Ni, Yan G., Wang, Ming-Dauh, Devalaraja-Narashimha, Kishor, Subramanian, Poorani, Ergelen, Rabia, Artan, Reha, Guner, Sukru Nail, Dalgic, Buket, Tsang, John, Belkaid, Yasmine, Ertem, Deniz, Baris, Safa, Lenardo, Michael J.

“…Complement hyperactivation, angiopathic thrombosis and protein-losing enteropathy (CHAPLE disease) is a lethal disease caused by genetic loss of the complement…”
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Molecular and temporal control of restimulation-induced cell death (RICD) in T lymphocytes by Lee, Katherine P, Epstein, Benjamin, Lake, Camille M, Snow, Andrew L

“…For effective adaptive immunity, T lymphocytes must rapidly expand and contract in an antigen-specific manner to effectively control invading pathogens and…”
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FOXP3, CD48 and autophagy confer the protection of CD4 and CD8 human T cells from T cell receptor restimulation-induced cell death by Voss, Kelsey, Lott, Nathaniel M, Lake, Camille, Bauman, Bradly M, Dorjbal, Batsukh, Luthers, Christopher R, Arjunaraja, Swadhinya, Dalgard, Clifton L, Snow, Andrew L

“…Abstract The proliferation and contraction of activated effector T cells must be carefully coordinated to maintain immune homeostasis. This is achieved in part…”
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FOXP3 protects conventional human T cells from premature restimulation-induced cell death by Voss, Kelsey, Lake, Camille, Luthers, Christopher R., Lott, Nathaniel M., Dorjbal, Batsukh, Arjunaraja, Swadhinya, Bauman, Bradly M., Soltis, Anthony R., Sukumar, Gauthaman, Dalgard, Clifton L., Snow, Andrew L.

“…The adaptive immune response relies on specific apoptotic programs to maintain homeostasis. Conventional effector T cell (Tcon) expansion is constrained by…”
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Impairment in the mesohippocampal dopamine circuit following exposure to the brominated flame retardant, HBCDD by Pham-Lake, Camille, Aronoff, Elizabeth B, Camp, Chad R, Vester, Aimee, Peters, Sam J, Caudle, W.Michael

“…Highlights • Brominated flame retardants (BFR) are associated with neurobehavioral deficits • HBCDD exposure decreased presynaptic dopaminergic proteins in the…”
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461. Classical Antigen Presenting Cell Activation Correlates with T Cell Immunity and COVID-19 Severity by Lu, Zhongyan, Pena-DaMata, Jarina, Pohida, Katherine, Lake, Camille, Epsi, Nusrat J, Richard, Stephanie A, Agan, Brian, Pollett, Simon, Simons, Mark P, Dalgard, Clifton, Blair, Paul W, Chenoweth, Josh, Snow, Andrew L, Burgess, Timothy, Malloy, Allison M

“…Abstract Background The initial response of immune cells against respiratory viruses often determines the severity and duration of disease. The early…”
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