Search Results - "Lake, A. A."
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What we know so far: COVID-19 current clinical knowledge and research
Published in Clinical medicine (London, England) (01-03-2020)“…In December 2019, health authorities in Wuhan, China, identified a cluster of pneumonia cases of unknown aetiology linked to the city's South China Seafood…”
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Changes in household food and drink purchases following restrictions on the advertisement of high fat, salt, and sugar products across the Transport for London network: A controlled interrupted time series analysis
Published in PLoS medicine (17-02-2022)“…Restricting the advertisement of products with high fat, salt, and sugar (HFSS) content has been recommended as a policy tool to improve diet and tackle…”
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Glucolipotoxicity: A Proposed Etiology for Wooden Breast and Related Myopathies in Commercial Broiler Chickens
Published in Frontiers in physiology (13-03-2020)“…Wooden breast is one of several myopathies of fast-growing commercial broilers that has emerged as a consequence of intensive selection practices in the…”
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Where is the greatest potential for resource recovery in wastewater treatment plants?
Published in Water research (Oxford) (15-07-2022)“…•Structured approach developed to select regional resource recovery strategies.•Multi-criteria analysis considering cost, carbon, 6 capitals, market and…”
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Low cost satellite constellations for nearly continuous global coverage
Published in Nature communications (10-01-2020)“…Satellite services are fundamental to the global economy, and their design reflects a tradeoff between coverage and cost. Here, we report the discovery of two…”
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Two Cheers for Bargaining Theory: Assessing Rationalist Explanations of the Iraq War
Published in International security (01-12-2010)“…The Iraq War has received little sustained analysis from scholars of international relations. I assess the rationalist approach to war-or, simply, bargaining…”
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A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice
Published in BMC cancer (16-10-2017)“…Cytotoxic chemotherapeutics form the cornerstone of systemic treatment of many cancers. Patients are dosed at maximum tolerated dose (MTD), which is carefully…”
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Weighing the risks and benefits of flowering early in the spring for the woody perennial Prunus pumila
Published in American journal of botany (18-10-2024)“…There are advantages to flowering early in the spring, including greater pollinator fidelity and longer fruit maturation time. But plant phenology has advanced…”
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Chemotherapy and immunotherapy: mapping the road ahead
Published in Current opinion in immunology (01-04-2016)“…Highlights • Essential constituents of immunogenic cell death. • Chemotherapy-induced modulation of antigen-presenting and immunosuppressive cells. • Clinical…”
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Legitimating Power: The Domestic Politics of U.S. International Hierarchy
Published in International security (01-10-2013)“…The United States has maintained international hierarchies over the Western Hemisphere for more than a century and over Western Europe for nearly seven…”
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White Man’s IR: An Intellectual Confession
Published in Perspectives on politics (01-12-2016)“…Drawing largely on my own career in academia, I elaborate on the need for greater gender, racial and other forms of diversity in International Relations…”
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Genetic basis and identification of candidate genes for wooden breast and white striping in commercial broiler chickens
Published in Scientific reports (24-03-2021)“…Wooden breast (WB) and white striping (WS) are highly prevalent and economically damaging muscle disorders of modern commercial broiler chickens characterized…”
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The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma
Published in Nature genetics (01-07-2011)“…Malignant pleural mesotheliomas (MPMs) often show CDKN2A and NF2 inactivation, but other highly recurrent mutations have not been described. To identify…”
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Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity
Published in PloS one (23-04-2013)“…Several chemotherapeutics exert immunomodulatory effects. One of these is the nucleoside analogue gemcitabine, which is widely used in patients with lung…”
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Cancer chemotherapy: insights into cellular and tumor microenvironmental mechanisms of action
Published in Frontiers in oncology (29-07-2022)“…Chemotherapy has historically been the mainstay of cancer treatment, but our understanding of what drives a successful therapeutic response remains limited…”
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An application of hybrid life cycle assessment as a decision support framework for green supply chains
Published in International journal of production research (02-11-2015)“…In an effort to achieve sustainable operations, green supply chain management has become an important area for firms to concentrate on due to its inherent…”
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Immunotherapy and chemotherapy - a practical partnership
Published in Nature reviews. Cancer (01-05-2005)“…This article discusses how recent data have altered the way we understand how dying tumour cells, particularly those killed by chemotherapy, engage with…”
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The effect of hypoglycaemia during hospital admission on health‐related outcomes for people with diabetes: a systematic review and meta‐analysis
Published in Diabetic medicine (01-11-2019)“…Aim To assess the health‐related outcomes of hypoglycaemia for people with diabetes admitted to hospital; specifically, hospital length of stay and mortality…”
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Obesogenic urban form: Theory, policy and practice
Published in Health & place (01-12-2009)“…There is a growing body of research, which suggests that many contemporary urban environments do not support healthy lifestyle choices and are implicated in…”
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Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses
Published in Frontiers in immunology (14-10-2020)“…Immunotherapies have revolutionized cancer treatment. In particular, immune checkpoint therapy (ICT) leads to durable responses in some patients with some…”
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