Search Results - "Lakay, Francisco"

The spread of tomato yellow leaf curl virus from the Middle East to the world by Lefeuvre, Pierre, Martin, Darren P, Harkins, Gordon, Lemey, Philippe, Gray, Alistair J A, Meredith, Sandra, Lakay, Francisco, Monjane, Adérito, Lett, Jean-Michel, Varsani, Arvind, Heydarnejad, Jahangir

“…The ongoing global spread of Tomato yellow leaf curl virus (TYLCV; Genus Begomovirus, Family Geminiviridae) represents a serious looming threat to tomato…”
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Identification and control for the effects of bioinformatic globin depletion on human RNA-seq differential expression analysis by Sheerin, Dylan, Lakay, Francisco, Esmail, Hanif, Kinnear, Craig, Sansom, Bianca, Glanzmann, Brigitte, Wilkinson, Robert J., Ritchie, Matthew E., Coussens, Anna K.

“…When profiling blood samples by RNA-sequencing (RNA-seq), RNA from haemoglobin (Hgb) can account for up to 70% of the transcriptome. Due to considerations of…”
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Inducible resistance to maize streak virus by Shepherd, Dionne N, Dugdale, Benjamin, Martin, Darren P, Varsani, Arvind, Lakay, Francisco M, Bezuidenhout, Marion E, Monjane, Adérito L, Thomson, Jennifer A, Dale, James, Rybicki, Edward P

“…Maize streak virus (MSV), which causes maize streak disease (MSD), is the major viral pathogenic constraint on maize production in Africa. Type member of the…”
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Testing novel strategies for patients hospitalised with HIV-associated disseminated tuberculosis (NewStrat-TB): protocol for a randomised controlled trial by Namale, Phiona E, Boloko, Linda, Vermeulen, Marcia, Haigh, Kate A, Bagula, Fortuna, Maseko, Alexis, Sossen, Bianca, Lee-Jones, Scott, Msomi, Yoliswa, McIlleron, Helen, Mnguni, Ayanda Trevor, Crede, Thomas, Szymanski, Patryk, Naude, Jonathan, Ebrahim, Sakeena, Vallie, Yakoob, Moosa, Muhammed Shiraz, Bandeker, Ismail, Hoosain, Shakeel, Nicol, Mark P, Samodien, Nazlee, Centner, Chad, Dowling, Wentzel, Denti, Paolo, Gumedze, Freedom, Little, Francesca, Parker, Arifa, Price, Brendon, Schietekat, Denzil, Simmons, Bryony, Hill, Andrew, Wilkinson, Robert J, Oliphant, Ida, Hlungulu, Siphokazi, Apolisi, Ivy, Toleni, Monica, Asare, Zimkhitha, Mpalali, Mkanyiseli Kenneth, Boshoff, Erica, Prinsloo, Denise, Lakay, Francisco, Bekiswa, Abulele, Jackson, Amanda, Barnes, Ashleigh, Johnson, Ryan, Wasserman, Sean, Maartens, Gary, Barr, David, Schutz, Charlotte, Meintjes, Graeme

“…HIV-associated tuberculosis (TB) contributes disproportionately to global tuberculosis mortality. Patients hospitalised at the time of the diagnosis of…”
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Molecular diversity, geographic distribution and host range of monocot-infecting mastreviruses in Africa and surrounding islands by Kraberger, Simona, Saumtally, Salem, Pande, Daniel, Khoodoo, Michel H.R., Dhayan, Sonalall, Dookun-Saumtally, Asha, Shepherd, Dionne N., Hartnady, Penelope, Atkinson, Richard, Lakay, Francisco M., Hanson, Britt, Redhi, Devasha, Monjane, Adérito L., Windram, Oliver P., Walters, Matthew, Oluwafemi, Sunday, Michel-Lett, Jean, Lefeuvre, Pierre, Martin, Darren P., Varsani, Arvind

“…•Discovery of MSV strain C isolates infecting maize in Kenya.•MSV strain G infecting Digitaria sp. on the island of Grand Canaria.•MSV and PanSV have very…”
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A rep-based hairpin inhibits replication of diverse maize streak virus isolates in a transient assay by OWOR, Betty E, MARTIN, Darren P, RYBICKI, Edward P, THOMSON, Jennifer A, BEZUIDENHOUT, Marion E, LAKAY, Francisco M, SHEPHERD, Dionne N

“…Maize streak disease, caused by the A strain of the African endemic geminivirus, maize streak mastrevirus (MSV-A), threatens the food security and livelihoods…”
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Adaptive evolution by recombination is not associated with increased mutation rates in Maize streak virus by Monjane, Adérito L, Pande, Daniel, Lakay, Francisco, Shepherd, Dionne N, van der Walt, Eric, Lefeuvre, Pierre, Lett, Jean-Michel, Varsani, Arvind, Rybicki, Edward P, Martin, Darren P

“…Single-stranded (ss) DNA viruses in the family Geminiviridae are proving to be very useful in real-time evolution studies. The high mutation rate of…”
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Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity by Riou, Catherine, Keeton, Roanne, Moyo-Gwete, Thandeka, Hermanus, Tandile, Kgagudi, Prudence, Baguma, Richard, Valley-Omar, Ziyaad, Smith, Mikhail, Tegally, Houriiyah, Doolabh, Deelan, Iranzadeh, Arash, Tyers, Lynn, Mutavhatsindi, Hygon, Tincho, Marius B, Benede, Ntombi, Marais, Gert, Chinhoyi, Lionel R, Mennen, Mathilda, Skelem, Sango, du Bruyn, Elsa, Stek, Cari, de Oliveira, Tulio, Williamson, Carolyn, Moore, Penny L, Wilkinson, Robert J, Ntusi, Ntobeko A B, Burgers, Wendy A

“…SARS-CoV-2 variants that escape neutralization and potentially affect vaccine efficacy have emerged. T cell responses play a role in protection from…”
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Effects of tuberculosis and/or HIV-1 infection on COVID-19 presentation and immune response in Africa by du Bruyn, Elsa, Stek, Cari, Daroowala, Remi, Said-Hartley, Qonita, Hsiao, Marvin, Schafer, Georgia, Goliath, Rene T., Abrahams, Fatima, Jackson, Amanda, Wasserman, Sean, Allwood, Brian W., Davis, Angharad G., Lai, Rachel P.-J., Coussens, Anna K., Wilkinson, Katalin A., de Vries, Jantina, Tiffin, Nicki, Cerrone, Maddalena, Ntusi, Ntobeko A. B., Riou, Catherine, Wilkinson, Robert J.

“…Few studies from Africa have described the clinical impact of co-infections on SARS-CoV-2 infection. Here, we investigate the presentation and outcome of…”
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Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa by Tamuhla, Tsaone, Coussens, Anna K, Abrahams, Maleeka, Blumenthal, Melissa J, Lakay, Francisco, Wilkinson, Robert J, Riou, Catherine, Raubenheimer, Peter, Dave, Joel A, Tiffin, Nicki

“…Background There is limited knowledge regarding African genetic drivers of disease due to prohibitive costs of large-scale genomic research in Africa. Methods…”
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Replication modes of Maize streak virus mutants lacking RepA or the RepA–pRBR interaction motif by Ruschhaupt, Moritz, Martin, Darren P, Lakay, Francisco, Bezuidenhout, Marion, Rybicki, Edward P, Jeske, Holger, Shepherd, Dionne N

“…Abstract The plant-infecting mastreviruses (family Geminiviridae ) express two distinct replication-initiator proteins, Rep and RepA. Although RepA is…”
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Replication modes of Maize streak virus mutants lacking RepA or the RepAapRBR interaction motif by Ruschhaupt, Moritz, Martin, Darren, Lakay, Francisco, Bezuidenhout, Marion, Rybicki, Edward, Jeske, Holger, Shepherd, Dionne

“…The plant-infecting mastreviruses (family Geminiviridae) express two distinct replication-initiator proteins, Rep and RepA. Although RepA is essential for…”
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Extensive recombination-induced disruption of genetic interactions is highly deleterious but can be partially reversed by small numbers of secondary recombination events by Monjane, Adérito L, Martin, Darren P, Lakay, Francisco, Muhire, Brejnev M, Pande, Daniel, Varsani, Arvind, Harkins, Gordon, Shepherd, Dionne N, Rybicki, Edward P

“…Although homologous recombination can potentially provide viruses with vastly more evolutionary options than are available through mutation alone, there are…”
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Complete sequences of tomato leaf curl Palampur virus isolates infecting cucurbits in Iran by Heydarnejad, Jahangir, Mozaffari, Azadeh, Massumi, Hossain, Fazeli, Roya, Gray, Alistair J. A, Meredith, Sandra, Lakay, Francisco, Shepherd, Dionne N, Martin, Darren P, Varsani, Arvind

“…Tomato leaf curl disease (TLCD) and and tomato yellow leaf curl (TYLCD) is caused by a number of begomovirus species that collectively threaten tomato…”
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The Spread of Tomato Yellow Leaf Curl Virus from the Middle East to the World: e1001164 by Lefeuvre, Pierre, Martin, Darren P, Harkins, Gordon, Lemey, Philippe, Gray, Alistair JA, Meredith, Sandra, Lakay, Francisco, Monjane, Adérito, Lett, Jean-Michel, Varsani, Arvind, Heydarnejad, Jahangir

“…The ongoing global spread of Tomato yellow leaf curl virus (TYLCV; Genus Begomovirus, Family Geminiviridae) represents a serious looming threat to tomato…”
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Bromus catharticus striate mosaic virus: a new mastrevirus infecting Bromus catharticus from Australia by Hadfield, James, Martin, Darren P, Stainton, Daisy, Kraberger, Simona, Owor, Betty E, Shepherd, Dionne N, Lakay, Francisco, Markham, Peter G, Greber, Ray S, Briddon, Rob W, Varsani, Arvind

“…Although monocotyledonous-plant-infecting mastreviruses (in the family Geminiviridae) are known to cause economically significant crop losses in certain areas…”
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Inducible Resistance to Maize Streak Virus: e105932 by Shepherd, Dionne N, Dugdale, Benjamin, Martin, Darren P, Varsani, Arvind, Lakay, Francisco M, Bezuidenhout, Marion E, Monjane, Aderito L, Thomson, Jennifer A, Dale, James, Rybicki, Edward P

“…Maize streak virus (MSV), which causes maize streak disease (MSD), is the major viral pathogenic constraint on maize production in Africa. Type member of the…”
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