Search Results - "Lajos, Papp"

New Trends in the Quality Control of Enantiomeric Drugs: Quality by Design-Compliant Development of Chiral Capillary Electrophoresis Methods by Orlandini, Serena, Hancu, Gabriel, Szabó, Zoltán-István, Modroiu, Adriana, Papp, Lajos-Attila, Gotti, Roberto, Furlanetto, Sandra

“…Capillary electrophoresis (CE) is a potent method for analyzing chiral substances and is commonly used in the enantioseparation and chiral purity control of…”
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Simultaneous determination of enantiomeric and organic impurities of vildagliptin on a cellulose tris(3-chloro-4-methylphenylcarbamate) column under revered-phase conditions by Papp, Lajos-Attila, Hancu, Gabriel, Szabó, Zoltán-István

“…A new, reversed-phase HPLC (RP-HPLC) method was developed for the simultaneous determination of the dipeptidyl-peptidase-IV-inhibitor antidiabetic drug…”
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Photosensitivity Reactions Induced by Photochemical Degradation of Drugs by Klelemen, Hajnal, Hancu, Gabriel, Kacsó, Edina, Papp, Lajos-Attila

“…Photochemical degradation of drugs can lead to degradation products with potential toxic or allergizing effects for the human body. A significant amount of…”
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Vivianite formation as indicator of human impact in porous sediments by Árpád, Csámer, Lajos, Papp, Ferenc, Kristály, Sándor, Szakáll, Péter, Rózsa

“…Environmental geological survey of a chemical works situated in NE Hungary has been performed for decades. Up till now, several hundreds of drillings of…”
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Calming Hungarian Grey Cattle in Headlocks Using Processed Nasal Vocalization of a Mother Cow by Lenner, Ádám, Papp, Zoltán Lajos, Szabó, Csaba, Komlósi, István

“…Sound analysis is an important field of research for improving precision livestock farming systems. If the information carried by livestock sounds is…”
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Is it Time to Migrate to Liquid Chromatography Automated Platforms in the Clinical Laboratory? A Brief Point of View by Papp, Lajos-Attila, Imre, Silvia, Bálint, István, Lungu, Andreea-Ioana, Mărcutiu, Petra-Edina, Papp, Júlia, Ion, Valentin

“…Abstract Liquid chromatography coupled to mass spectrometry already started to surpass the major drawbacks in terms of sensitivity, specificity and…”
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The Use of Dual Cyclodextrin Chiral Selector Systems in the Enantioseparation of Pharmaceuticals by Capillary Electrophoresis: An Overview by Hancu, Gabriel, Papp, Lajos Attila, Tóth, Gergő, Kelemen, Hajnal

“…Cyclodextrin (CD) derivatives are the most efficient and frequently used chiral selectors (CSs) in capillary electrophoresis (CE). There are situations when…”
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Application of Experimental Design Methodologies in the Enantioseparation of Pharmaceuticals by Capillary Electrophoresis: A Review by Hancu, Gabriel, Orlandini, Serena, Papp, Lajos Attila, Modroiu, Adriana, Gotti, Roberto, Furlanetto, Sandra

“…Chirality is one of the major issues in pharmaceutical research and industry. Capillary electrophoresis (CE) is an interesting alternative to the more…”
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The Use of Antibiotics as Chiral Selectors in Capillary Electrophoresis: A Review by Hancu, Gabriel, Papp, Lajos Attila, Szekely-Szentmiklosi, Blanka, Kelemen, Hajnal

“…Chirality is becoming an essential issue in modern pharmaceutical research as regulatory agencies emphasize the safety and efficiency of enantiomers in drug…”
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Comprehensive Review on Chiral Stationary Phases in Single-Column Simultaneous Chiral-Achiral HPLC Separation Methods by Papp, Lajos Attila, Szabó, Zoltán István, Hancu, Gabriel, Farczádi, Lénárd, Mircia, Eleonora

“…This comprehensive review explores the utilization of chiral stationary phases (CSPs) in the context of single-column simultaneous chiral-achiral…”
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Chiral Discrimination of Mexiletine Enantiomers by Capillary Electrophoresis Using Cyclodextrins as Chiral Selectors and Experimental Design Method Optimization by Cârcu-Dobrin, Melania, Hancu, Gabriel, Papp, Lajos Attila, Fülöp, Ibolya

“…Mexiletine (MXL) is a class IB antiarrhythmic agent, acting as a non-selective voltage-gated sodium channel blocker, used in therapy as a racemic mixture…”
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Determination of Chiral Impurity of Naproxen in Different Pharmaceutical Formulations Using Polysaccharide-Based Stationary Phases in Reversed-Phased Mode by Papp, Lajos-Attila, Krizbai, Sarolta, Dobó, Máté, Hancu, Gabriel, Szabó, Zoltán-István, Tóth, Gergő

“…A novel, validated, reversed-phase (RP), chiral high performance liquid chromatography (HPLC) method was developed for the enantiopurity control analysis of…”
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Enantioseparation and molecular docking study of selected chiral pharmaceuticals on a commercialized phenylcarbamate-β-cyclodextrin column using polar organic mode by Dobó, Máté, Ádám, Márk, Fiser, Béla, Papp, Lajos Attila, Dombi, Gergely, Sekkoum, Khaled, Szabó, Zoltán-István, Tóth, Gergő

“…The chiral separation capability of Chiral-CD-Ph column, containing phenylcarbamate-β-cyclodextrin as the chiral selector in polar organic mode was…”
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Mitogen-activated Protein Kinases p38 and ERK 1/2 Mediate the Wall Stress-induced Activation of GATA-4 Binding in Adult Heart by Tenhunen, Olli, Sármán, Balázs, Kerkelä, Risto, Szokodi, István, Papp, Lajos, Tóth, Miklós, Ruskoaho, Heikki

“…The zinc finger transcription factor GATA-4 has been implicated as a critical regulator of inducible cardiac gene expression and as a potential mediator of the…”
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Development of a Chiral Capillary Electrophoresis Method for the Enantioseparation of Verapamil Using Cyclodextrins as Chiral Selectors and Experimental Design Optimization by Cârcu-Dobrin, Melania, Hancu, Gabriel, Papp, Lajos Attila, Fülöp, Ibolya, Kelemen, Hajnal

“…Chirality is a property of asymmetry which determines the pharmacokinetic and pharmacological profiles of optically active pharmaceuticals. Verapamil (VER), a…”
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Chiral Separation of Vildagliptin by Capillary Electrophoresis—The Study of Enantiomeric Complexation by Papp, Lajos Attila, Hancu, Gabriel, Szabó, Zoltán István, Székely-Szentmiklósi, Blanka, Gáti, Tamás, Fiser, Béla, Kraszni, Márta, Tóth, Gergő

“…Vildagliptin (VIL) is a dipeptidyl peptidase-4 inhibitor used in the treatment of type 2 diabetes mellitus; in therapy, it is available as the enantiomerically…”
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Simultaneous determination of amoxicillin and clavulanic acid in pharmaceutical preparations by capillary zone electrophoresis by Hancu, Gabriel, Neacşu, Anamaria, Papp, Lajos Attila, Ciurba, Adriana

“…ABSTRACT Clavulanic acid enhances the antibacterial spectrum of amoxicillin by rendering most β-lactamase producing isolates susceptible to the drug. A fast,…”
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Chiral discrimination of amlodipine from pharmaceutical products using capillary electrophoresis by Cârcu-Dobrin, Melania, Sabău, Alexandra Georgiana, Hancu, Gabriel, Árpád, Gyéresi, Rusu, Aura, Kelemen, Hajnal, Papp, Lajos Attila, Cârje, Anca

“…The present work describes the development of a capillary electrophoresis (CE) method for the chiral discrimination of amlodipine (AML) enantiomers using…”
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Development of a generic method for the determination of proton-pump inhibitors by capillary zoneelectrophoresis by Papp, Lajos Attila, Gyéresi, Árpád, Hancu, Gabriel, Mircia, Eleonora, Kelemen, Hajnal

“…A generic capillary zone electrophoresis method was developed for the analysis of four proton pump inhibitors: omeprazole, pantoprazole, lansoprazole and…”
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Role of poly(ADP-ribose) polymerase activation in endotoxin-induced cardiac collapse in rodents by Pacher, Pál, Cziráki, Attila, Mabley, Jon G, Liaudet, Lucas, Papp, Lajos, Szabó, Csaba

“…Reactive oxygen and nitrogen species are overproduced in the cardiovascular system during circulatory shock. Oxidant-induced cell injury involves the…”
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