Search Results - "Lajmi, Nesrine"
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Cancer‐testis antigen expression and its epigenetic modulation in acute myeloid leukemia
Published in American journal of hematology (01-11-2011)“…Cancer‐testis antigens (CTA) represent attractive targets for tumor immunotherapy. However, a broad picture of CTA expression in acute myeloid leukemia (AML)…”
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The cytokine/chemokine pattern in the bone marrow environment of multiple myeloma patients
Published in Experimental hematology (01-10-2010)“…Objective The interaction of multiple myeloma (MM) with its bone marrow (BM) microenvironment is important for the homing pattern, survival, and proliferation…”
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3
Cancer-testis antigens MAGE-C1/CT7 and MAGE-A3 promote the survival of multiple myeloma cells
Published in Haematologica (Roma) (01-05-2010)“…Multiple myeloma is a life-threatening disease and despite the introduction of stem cell transplantation and novel agents such as thalidomide, lenalidomide,…”
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Challenges and solutions to system-wide use of precision oncology as the standard of care paradigm
Published in Cambridge prisms. Precision medicine (2024)“…The personalised oncology paradigm remains challenging to deliver despite technological advances in genomics-based identification of actionable variants…”
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Surface molecule CD229 as a novel target for the diagnosis and treatment of multiple myeloma
Published in Haematologica (Roma) (01-10-2011)“…To date, multiple myeloma remains an incurable malignancy due to the persistence of minimal residual disease in the bone marrow. In this setting, monoclonal…”
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6
The trifunctional antibody catumaxomab amplifies and shapes tumor-specific immunity when applied to gastric cancer patients in the adjuvant setting
Published in Human vaccines & immunotherapeutics (01-12-2013)“…Background: Patients with gastric cancer benefit from perioperative chemotherapy, however, treatment is toxic and many patients will relapse. The trifunctional…”
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7
Longitudinal Analysis of Tetanus- and Influenza-Specific IgG Antibodies in Myeloma Patients
Published in Clinical & developmental immunology (01-01-2012)“…Background. Multiple myeloma (MM) and its therapies may induce a severely compromised humoral immunity. We have performed a longitudinal analysis of…”
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8
Patients with Multiple Myeloma Develop SOX2-Specific Autoantibodies after Allogeneic Stem Cell Transplantation
Published in Clinical & developmental immunology (01-01-2011)“…The occurrence of SOX2-specific autoantibodies seems to be associated with an improved prognosis in patients with monoclonal gammopathy of undetermined…”
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9
Cancer‐testis antigen MAGEC2 promotes proliferation and resistance to apoptosis in Multiple Myeloma
Published in British journal of haematology (01-12-2015)“…Summary Cancer‐testis antigens belonging to the MAGE family of genes, such as MAGEC2, are commonly and specifically expressed in Multiple Myeloma (MM) and are…”
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10
Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma
Published in Journal of translational medicine (20-06-2015)“…Most patients with multiple myeloma (MM) will relapse after an initial response and eventually succumb to their disease. This is due to the persistence of…”
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Role of Interleukin 16 in Multiple Myeloma
Published in JNCI : Journal of the National Cancer Institute (03-07-2012)“…Multiple myeloma is a malignancy characterized by the expansion of a plasma cell clone that localizes to the human bone marrow. Myeloma cells and bone marrow…”
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Abstract 4729: MAGE-C2 promotes proliferation and enhances resistance to p53 DNA damage-mediated apoptosis in multiple myeloma
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Background: MAGE-C2 is member of the MAGE class I family of genes and is commonly and specifically expressed in Multiple Myeloma (MM). Expression of…”
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13
An optimized assay for the enumeration of antigen-specific memory B cells in different compartments of the human body
Published in Journal of immunological methods (30-06-2010)“…In the framework of our current study we set out to develop an optimized assay for the quantification of antigen-specific B cells in different compartments of…”
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14
Cancer-Testis Antigen MAGE-C2/CT10 Promotes Proliferation and Enhances Resistance to p53 Mediated Apoptosis in Multiple Myeloma
Published in Blood (16-11-2012)“…Abstract 1808 Cancer-testis antigens belonging to the MAGE class I family of genes are commonly expressed in Multiple Myeloma (MM). Expression of MAGE class I…”
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15
Expression, epigenetic regulation, and humoral immunogenicity of cancer-testis antigens in chronic myeloid leukemia
Published in Leukemia research (01-12-2010)“…Abstract Objective Cancer-testis (CT) antigens represent attractive targets for tumor immunotherapy based on their tumor-restricted expression and…”
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Abstract 2450: Surface molecule CD229 represents a possible target for the treatment of multiple myeloma
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract BACKGROUND AND OBJECTIVES: The majority of patients with multiple myeloma (MM) will eventually relapse and succumb to their disease even after high…”
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A Characteristic Cytokine/Chemokine Milieu Is Present in the Bone Marrow Environment of Multiple Myeloma Patients Before and After Allogeneic Stem Cell Transplantation
Published in Blood (20-11-2009)“…Abstract 2795 Poster Board II-771 The interaction of Multiple Myeloma (MM) with its bone marrow (BM) microenvironment is important for the homing, survival,…”
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18
NY-ESO-1 expression and immunogenicity in prostate cancer patients
Published in Tunisie Medicale (01-10-2011)“…Prostate cancer is the second leading cause of men cancer-related death. Cancer immunotherapy has been investigated as a treatment which might be instituted at…”
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19
Longitudinal Analysis of Tetanus- and Influenza-Specific IgG Antibodies in Myeloma Patients
Published in Clinical & developmental immunology (2012)“…Background. Multiple myeloma (MM) and its therapies may induce a severely compromised humoral immunity. We have performed a longitudinal analysis of…”
Get full text
Journal Article -
20
Patients with Multiple Myeloma Develop SOX2-Specific Autoantibodies after Allogeneic Stem Cell Transplantation
Published in Clinical & developmental immunology (2011)“…The occurrence of SOX2-specific autoantibodies seems to be associated with an improved prognosis in patients with monoclonal gammopathy of undetermined…”
Get full text
Journal Article