Search Results - "Lajis, Nordin HJ"
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Vasorelaxant activity of indole alkaloids from Tabernaemontana dichotoma
Published in Journal of natural medicines (01-01-2013)“…The aim of this study was to search for bioactive natural products from medicinal plants targeting vasorelaxant activity and we found the methanol extract from…”
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2
Anti-Diabetic Activity and Metabolic Changes Induced by Andrographis paniculata Plant Extract in Obese Diabetic Rats
Published in Molecules (Basel, Switzerland) (09-08-2016)“…Andrographis paniculata is an annual herb and widely cultivated in Southeast Asian countries for its medicinal use. In recent investigations, A. paniculata was…”
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3
STRUCTURE ELUCIDATION OF ANTIBACTERIAL COMPOUND FROM Ficus deltoidea Jack LEAVES
Published in Indonesian journal of chemistry (12-07-2011)“…An antibacterial compound has been isolated from Ficus deltoidea Jack leaves. Based on spectroscopic data (IR, 1H-NMR, 13C NMR 1D and 2D and MS), the structure…”
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4
The synthetic curcuminoid BHMC restores endotoxin-stimulated HUVEC dysfunction:Specific disruption on enzymatic activity of p38 MAPK
Published in European journal of pharmacology (15-02-2015)“…2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone (BHMC) has been proven to selectively inhibit the synthesis of proinflammatory mediators in…”
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5
Chrotacumines A−D, Chromone Alkaloids from Dysoxylum acutangulum
Published in Journal of natural products (Washington, D.C.) (23-10-2009)“…Four new chromone alkaloids, chrotacumines A−D (1−4), consisting of a 5,7-dihydroxy-2-methylchromone, an N-Me piperidine ring, and an ester side chain were…”
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6
Comparison of Antioxidative Properties of Carbazole Alkaloids from Murraya koenigii Leaves
Published in Journal of agricultural and food chemistry (22-10-2003)“…A new dimeric carbazole alkaloid, 8,10‘-[3,3‘,11,11‘-tetrahydro-9,9‘-dihydroxy-3,3‘,5,8‘-tetramethyl-3,3‘-bis(4-methyl-3-pentenyl)]bipyrano[3,2-a]carbazole…”
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In vivo study of tetraprenyltoluquinone, an anticancer compounds from Garcinia cowa Roxb
Published in Journal of young pharmacists (01-04-2017)“…Objective: To investigate the in vivo antitumor effect of TPTQ against H-460 lung cancer cell lines in nude mice. Materials and Methods: Female nude mice…”
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8
Curcumin-like diarylpentanoid analogues as melanogenesis inhibitors
Published in Journal of natural medicines (2012)“…Anti-melanogenesis screening of 47 synthesized curcumin-like diarylpentanoid analogues was performed to show that some had a potent inhibitory effect on the…”
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9
Antioxidant, radical-scavenging, anti-inflammatory, cytotoxic and antibacterial activities of methanolic extracts of some Hedyotis species
Published in Life sciences (1973) (11-03-2005)“…The antioxidant, radical-scavenging, anti-inflammatory, cytotoxic and antibacterial activities of methanolic extracts of seven Hedyotisspecies were…”
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10
A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc
Published in Molecules (Basel, Switzerland) (07-04-2011)“…A new abietene diterpene, kaempfolienol (5S,6S,7S,9S,10S,11R,13S-abiet-8(14)-enepenta-6,7,9,11,13-ol, 1), was isolated from a rhizome extract of Kaempferia…”
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11
Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood
Published in European journal of pharmacology (24-05-2006)“…Some chalcones, such as hydroxychalcones have been reported previously to inhibit major pro-inflammatory mediators such as nitric oxide (NO), prostaglandin E 2…”
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12
Discrimination of young and mature leaves of Melicope ptelefolia using 1H NMR and multivariate data analysis
Published in Food chemistry (15-05-2011)“…► PCA showed a clear discrimination between the young and mature leaves extracts by PC3 and PC4. ► PC3 and PC4 accounted for 11.2% and 8.5% of variation,…”
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13
Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum
Published in Tetrahedron letters (26-08-2009)“…Two novel triterpenes, acutaxylines A ( 1) and B ( 2) were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was…”
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14
Development and validation of a bioanalytical method for quantification of 2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) in rat plasma
Published in Molecules (Basel, Switzerland) (07-12-2012)“…A sensitive and accurate high performance liquid chromatography with ultraviolet/visible light detection (HPLC-UV/VIS) method for the quantification of…”
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15
Cytotoxic aaptamines from Malaysian Aaptos aaptos
Published in Marine drugs (01-03-2009)“…In a preliminary screen, Aaptos aaptos showed significant cytotoxic activity towards a panel of cell lines and was thus subjected to bioassay-guided isolation…”
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16
New vasorelaxant indole alkaloids, villocarines A–D from Uncaria villosa
Published in Bioorganic & medicinal chemistry (01-07-2011)“…Villocarines A–D ( 1– 4), four new indole alkaloids have been isolated from the leaves of Uncaria villosa (Rubiaceae) and their structures were elucidated by…”
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New class of acetylcholinesterase inhibitors from the stem bark of Knema laurina and their structural insights
Published in Bioorganic & medicinal chemistry letters (01-07-2011)“…Bioassay-guided extraction of the stem bark of Knema laurina showed the acetylcholinesterase (AChE) inhibitory activity of DCM and hexane fractions. Further…”
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18
A geranyl acetophenone targeting cysteinyl leukotriene synthesis prevents allergic airway inflammation in ovalbumin-sensitized mice
Published in Toxicology and applied pharmacology (01-03-2012)“…Asthma is associated with increased pulmonary inflammation and airway hyperresponsiveness. The current use of corticosteroids in the management of asthma has…”
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19
Vertical distribution and source identification of polycyclic aromatic hydrocarbons in anoxic sediment cores of Chini Lake, Malaysia: Perylene as indicator of land plant-derived hydrocarbons
Published in Applied geochemistry (01-09-2009)“…Four anoxic sediment cores were collected from Chini Lake, Malaysia in order to investigate the variability of polycyclic aromatic hydrocarbon (PAH) and…”
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Inhabitation Effect of Linoleic Acid, the Ingredient of Nigella sativa (Black Seed) on MDA-MB-231 and MCF-7 Human Breast Cancer Cells
Published in Journal of family & reproductive health (01-12-2010)“…Objective: The objective of this study was to investigate inhibition and anti-cancer effects of Linoleic acid on the MCF-7 and MDA-MB-231 human breast cancer…”
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