Search Results - "Laissue, J."

Effects of pulsed, spatially fractionated, microscopic synchrotron X-ray beams on normal and tumoral brain tissue by Bräuer-Krisch, E., Serduc, R., Siegbahn, E.A., Le Duc, G., Prezado, Y., Bravin, A., Blattmann, H., Laissue, J.A.

“…Microbeam radiation therapy (MRT) uses highly collimated, quasi-parallel arrays of X-ray microbeams of 50–600 keV, produced by third generation synchrotron…”
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Computational modelling of the cerebral cortical microvasculature: effect of x-ray microbeams versus broad beam irradiation by Merrem, A, Bartzsch, S, Laissue, J, Oelfke, U

“…Microbeam Radiation Therapy is an innovative pre-clinical strategy which uses arrays of parallel, tens of micrometres wide kilo-voltage photon beams to treat…”
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Survival of rats bearing advanced intracerebral F 98 tumors after glutathione depletion and microbeam radiation therapy: conclusions from a pilot project by Schültke, E, Bräuer-Krisch, E, Blattmann, H, Requardt, H, Laissue, J A, Hildebrandt, G

“…Resistance to radiotherapy is frequently encountered in patients with glioblastoma multiforme. It is caused at least partially by the high glutathione content…”
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Prospects for microbeam radiation therapy of brain tumours in children to reduce neurological sequelae by Laissue, JA, Blattmann, H, Wagner, H P, Grotzer, M A, Slatkin, D N

“…Microbeam radiation therapy (MRT), a form of experimental radiosurgery of tumours using multiple parallel, planar, micrometres‐wide, synchrotron‐generated…”
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Microbeam radiation therapy: Clinical perspectives by Grotzer, M.A, Schültke, E, Bräuer-Krisch, E, Laissue, J.A

“…Abstract Microbeam radiation therapy (MRT), a novel form of spatially fractionated radiotherapy (RT), uses arrays of synchrotron-generated X-ray microbeams…”
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Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands by Reubi, J C, Waser, B, Schaer, J C, Laissue, J A

“…Somatostatin receptors are known to be expressed in a large number of human tumours and represent the basis for in vivo tumour targeting. Stable somatostatin…”
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New technology enables high precision multislit collimators for microbeam radiation therapy by Bräuer-Krisch, E, Requardt, H, Brochard, T, Berruyer, G, Renier, M, Laissue, J A, Bravin, A

“…During the past decade microbeam radiation therapy has evolved from preclinical studies to a stage in which clinical trials can be planned, using spatially…”
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Synchrotron X-ray microtransections: a non invasive approach for epileptic seizures arising from eloquent cortical areas by Pouyatos, B., Nemoz, C., Chabrol, T., Potez, M., Bräuer, E., Renaud, L., Pernet-Gallay, K., Estève, F., David, O., Kahane, P., Laissue, J. A., Depaulis, A., Serduc, R.

“…Synchrotron-generated X-ray (SRX) microbeams deposit high radiation doses to submillimetric targets whilst minimizing irradiation of neighboring healthy…”
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Vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor subtypes in human tumors and their tissues of origin by REUBI, J. C, LÄDERACH, U, WASER, B, GEBBERS, J.-O, ROBBERECHT, P, LAISSUE, J. A

“…The evaluation of peptide receptors in man is needed not only to discover the physiological target tissues of a given peptide but also to identify diseases…”
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New irradiation geometry for microbeam radiation therapy by Bräuer-Krisch, E, Requardt, H, Régnard, P, Corde, S, Siegbahn, E, LeDuc, G, Brochard, T, Blattmann, H, Laissue, J, Bravin, A

“…Microbeam radiation therapy (MRT) has the potential to treat infantile brain tumours when other kinds of radiotherapy would be excessively toxic to the…”
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Synergy of gene-mediated immunoprophylaxis and microbeam radiation therapy for advanced intracerebral rat 9L gliosarcomas by Smilowitz, H M, Blattmann, H, Bräuer-Krisch, E, Bravin, A, Di Michiel, M, Gebbers, J-O, Hanson, A L, Lyubimova, N, Slatkin, D N, Stepanek, J, Laissue, J A

“…Microbeam radiation therapy (MRT), a novel experimental radiosurgery that largely spares the developing CNS and other normal tissues, is tolerated well by…”
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Synchrotron X-ray microbeams: A promising tool for drug-resistant epilepsy treatment by Studer, F, Serduc, R, Pouyatos, B, Chabrol, T, Bräuer-Krisch, E, Donzelli, M, Nemoz, C, Laissue, J.A, Estève, F, Depaulis, A

“…Abstract Epilepsy is one of the most important neurological diseases. It concerns about 1% of the population worldwide. Despite the discovery of new molecules,…”
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MOSFET dosimetry for microbeam radiation therapy at the European Synchrotron Radiation Facility by Bräuer-Krisch, E., Bravin, A., Lerch, M., Rosenfeld, A., Stepanek, J., Di Michiel, M., Laissue, J. A.

“…Preclinical experiments are carried out with ∼20–30 μm wide, ∼10 mm high parallel microbeams of hard, broad-“white”-spectrum x rays (∼50–600 keV) to…”
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Neurotensin receptors: a new marker for human ductal pancreatic adenocarcinoma by Reubi, J C, Waser, B, Friess, H, Büchler, M, Laissue, J

“…Background/Aims—New imaging possibilities for early diagnosis of the devastating exocrine pancreatic adenocarcinomas would be highly welcome. Recently,…”
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Subacute Neuropathological Effects of Microplanar Beams of X-Rays from a Synchrotron Wiggler by Slatkin, D. N., Spanne, P., Dilmanian, F. A., J.-O. Gebbers, Laissue, J. A.

“…Microplanar beam radiation therapy has been proposed to treat brain tumors by using a series of rapid exposures to an array of parallel x-ray beams, each beam…”
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SP-0343: Microbeam Radiation Therapy: Current status of the MRT pet trial project by Brauer-Krisch, E, Bartzsch, S, Berkvens, P, Crosbie, J, Brochard, T, Fournier, P, Laissue, J, Kaser-Hotz, B, Nemoz, C, Serduc, R

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Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation by Mazzucchelli, L, Hauser, C, Zgraggen, K, Wagner, H, Hess, M, Laissue, JA, Mueller, C

“…Interleukin-8 (IL-8) is a potent cytokine for recruitment and activation of neutrophils. To visualize its distribution in the intestinal mucosa and to…”
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Neuropathology of ablation of rat gliosarcomas and contiguous brain tissues using a microplanar beam of synchrotron‐wiggler‐generated X rays by Laissue, Jean A., Geiser, Gabrielle, Spanne, Per O., Dilmanian, F. Avraham, Gebbers, Jan‐Olaf, Geiser, Marianne, Wu, Xiao‐Ye, Makar, Michael S., Micca, Peggy L., Nawrocky, Marta M., Joel, Darrel D., Slatkin, Daniel N.

“…Adult‐rat‐brain tissues display an unusually high resistance to necrosis when serially irradiated with parallel, thin slices of a microplanar (i.e.,…”
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Radiosurgical palliation of aggressive murine SCCVII squamous cell carcinomas using synchrotron-generated X-ray microbeams by MIURA, M, BLATTMANN, H, BRÄUER-KRISCH, E, BRAVIN, A, HANSON, A. L, NAWROCKY, M. M, MICCA, P. L, SLATKIN, D. N, LAISSUE, J. A

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Substance-P receptors in human primary neoplasms: tumoral and vascular localization by Hennig, I M, Laissue, J A, Horisberger, U, Reubi, J C

“…Primary human neoplasms were examined for the presence of substance-P receptors by receptor autoradiography with 125I-labelled Bolton-Hunter substance P…”
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