Search Results - "Laird, J."

Transport investment and economic performance: A framework for project appraisal by Laird, James J., Venables, Anthony J.

“…The case for major transport investment is frequently made in terms of impact on economic performance. A recurring difficulty however faced by policy makers is…”
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Computed tomography‐defined low skeletal muscle index and density in cancer patients: observations from a systematic review by McGovern, Josh, Dolan, Ross D., Horgan, Paul G., Laird, Barry J., McMillan, Donald C.

“…Background Computed tomography (CT) analysis of body composition has garnered interest as a potential prognostic tool in those with cancer. A range of…”
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Stem Cell Trafficking in Tissue Development, Growth, and Disease by Laird, Diana J., von Andrian, Ulrich H., Wagers, Amy J.

“…Regulated movement of stem cells is critical for organogenesis during development and for homeostasis and repair in adulthood. Here we analyze the biological…”
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DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation by Sousa Martins, Joao P, Liu, Xueqing, Oke, Ashwini, Arora, Ripla, Franciosi, Federica, Viville, Stephan, Laird, Diana J, Fung, Jennifer C, Conti, Marco

“…Meiotic progression requires exquisitely coordinated translation of maternal messenger (m)RNA that has accumulated during oocyte growth. A major regulator of…”
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Insights from imaging the implanting embryo and the uterine environment in three dimensions by Arora, Ripla, Fries, Adam, Oelerich, Karina, Marchuk, Kyle, Sabeur, Khalida, Giudice, Linda C, Laird, Diana J

“…Although much is known about the embryo during implantation, the architecture of the uterine environment in which the early embryo develops is not well…”
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Apoptosis in the fetal testis eliminates developmentally defective germ cell clones by Nguyen, Daniel H., Soygur, Bikem, Peng, Su-Ping, Malki, Safia, Hu, Guang, Laird, Diana J.

“…Many germ cells are eliminated during development, long before oogenesis or spermatogenesis. In mouse fetal testes, the majority of germ cell apoptosis…”
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Porcine enterotoxigenic Escherichia coli: Antimicrobial resistance and development of microbial-based alternative control strategies by Laird, Tanya J., Abraham, Sam, Jordan, David, Pluske, John R., Hampson, David J., Trott, Darren J., O’Dea, Mark

“…•Global presence of ETEC strains resistant to critically important antimicrobials.•AMR stewardship and environmental concerns will impact on current…”
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Cancer cachexia: rationale for the MENAC (Multimodal-Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial by Solheim, Tora S, Laird, Barry J A, Balstad, Trude R, Bye, Asta, Stene, Guro, Baracos, Vickie, Strasser, Florian, Griffiths, Gareth, Maddocks, Matthew, Fallon, Marie, Kaasa, Stein, Fearon, Kenneth

“…Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional…”
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Vitamin D: determinants of status, indications for testing and knowledge in a convenience sample of Irish adults by Scully, Helena, Laird, Eamon J., Healy, Martin, Crowley, Vivion, Walsh, James Bernard, McCarroll, Kevin

“…Vitamin D deficiency is common in Irish adults, though there is limited research on its determinants, knowledge of vitamin D or indications for testing. We…”
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The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review by McGovern, Josh, Dolan, Ross D, Horgan, Paul G, Laird, Barry J, McMillan, Donald C

“…Frailty is a complex multifactorial syndrome characterised by a significant increase in vulnerability and worsened health outcomes. Despite a range of proposed…”
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Prognostic Tools in Patients With Advanced Cancer: A Systematic Review by Simmons, Claribel P.L., MBChB, MRCP, McMillan, Donald C., PhD, McWilliams, Kerry, MBChB, MRCP, Sande, Tonje A., MD, PhD, Fearon, Kenneth C., MD, Tuck, Sharon, BSc, Fallon, Marie T., MD, Laird, Barry J., MD

“…Abstract Purpose In 2005, the European Association for Palliative Care made recommendations for prognostic markers in advanced cancer. Since then, prognostic…”
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Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling by Cantú, Andrea V, Altshuler-Keylin, Svetlana, Laird, Diana J

“…Inheritance depends on the expansion of a small number of primordial germ cells (PGCs) in the early embryo. Proliferation of mammalian PGCs is concurrent with…”
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A systematic review examining the relationship between cytokines and cachexia in incurable cancer by Paval, D. Robert, Patton, Rebekah, McDonald, James, Skipworth, Richard J.E., Gallagher, Iain J., Laird, Barry J.

“…Cancer cachexia is an unmet clinical need that affects more than 50% of patients with cancer. The systemic inflammatory response, which is mediated by a…”
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Comparison of the prognostic value of ECOG-PS, mGPS and BMI/WL: Implications for a clinically important framework in the assessment and treatment of advanced cancer by Dolan, Ross D., Daly, Louise, Sim, Wei M.J., Fallon, Marie, Ryan, Aoife, McMillan, Donald C., Laird, Barry J.

“…The systemic inflammatory response is associated with the loss of lean tissue, anorexia, weakness, fatigue and reduced survival in patients with advanced…”
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Increase in Colorado Tick Fever Virus Disease Cases and Effect of COVID-19 Pandemic on Behaviors and Testing Practices, Montana, 2020 by Soto, Raymond A, Baldry, Erika, Vahey, Grace M, Lehman, Jennifer, Silver, Margaret, Panella, Amanda, Brault, Aaron C, Hughes, Holly R, Fitzpatrick, Kelly A, Velez, Jason, Biggerstaff, Brad J, Wolff, Brent, Randolph, Jean, Ruth, Laird J, Staples, J Erin, Gould, Carolyn V

“…In 2020, Montana, USA, reported a large increase in Colorado tick fever (CTF) cases. To investigate potential causes of the increase, we conducted a…”
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The use of opioids in cancer patients with renal impairment—a systematic review by Sande, Tonje A., Laird, Barry J. A., Fallon, Marie T.

“…Purpose Opioids are recommended for moderate to severe cancer pain; however, in patients with cancer, impaired renal function can affect opioid metabolism. The…”
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Differential susceptibility of male and female germ cells to glucocorticoid-mediated signaling by Cincotta, Steven A, Richardson, Nainoa, Foecke, Mariko H, Laird, Diana J

“…While physiologic stress has long been known to impair mammalian reproductive capacity through hormonal dysregulation, mounting evidence now suggests that…”
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Evaluation of Serial Testing After Exposure to COVID-19 in Early Care and Education Facilities, Illinois, March–May 2022 by Holman, Emily J., Winfield, Christina M., Borkowf, Craig B., Kauerauf, Judy, Baur, Courtney, Ahmed, Sana, Funk, Michelle, Pinsoneault, Anna, Barnes, Arti, Hutcherson, Hailee, Oberholtzer, Zach, Carter, Brittani, Ruth, Laird J., Thomas, Ebony S.

“…Objective: To understand SARS-CoV-2 transmission in early care and education (ECE) settings, we implemented a Test to Stay (TTS) strategy, which allowed…”
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Ror2 enhances polarity and directional migration of primordial germ cells by Laird, Diana J, Altshuler-Keylin, Svetlana, Kissner, Michael D, Zhou, Xin, Anderson, Kathryn V

“…The trafficking of primordial germ cells (PGCs) across multiple embryonic structures to the nascent gonads ensures the transmission of genetic information to…”
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Postnatal oogenesis leads to an exceptionally large ovarian reserve in naked mole-rats by Brieño-Enríquez, Miguel Angel, Faykoo-Martinez, Mariela, Goben, Meagan, Grenier, Jennifer K., McGrath, Ashley, Prado, Alexandra M., Sinopoli, Jacob, Wagner, Kate, Walsh, Patrick T., Lopa, Samia H., Laird, Diana J., Cohen, Paula E., Wilson, Michael D., Holmes, Melissa M., Place, Ned J.

“…In the long-lived naked mole-rat (NMR), the entire process of oogenesis occurs postnatally. Germ cell numbers increase significantly in NMRs between postnatal…”
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