Search Results - "Laird, Barry J"

Computed tomography‐defined low skeletal muscle index and density in cancer patients: observations from a systematic review by McGovern, Josh, Dolan, Ross D., Horgan, Paul G., Laird, Barry J., McMillan, Donald C.

“…Background Computed tomography (CT) analysis of body composition has garnered interest as a potential prognostic tool in those with cancer. A range of…”
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Prognostic Tools in Patients With Advanced Cancer: A Systematic Review by Simmons, Claribel P.L., MBChB, MRCP, McMillan, Donald C., PhD, McWilliams, Kerry, MBChB, MRCP, Sande, Tonje A., MD, PhD, Fearon, Kenneth C., MD, Tuck, Sharon, BSc, Fallon, Marie T., MD, Laird, Barry J., MD

“…Abstract Purpose In 2005, the European Association for Palliative Care made recommendations for prognostic markers in advanced cancer. Since then, prognostic…”
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Cancer cachexia: rationale for the MENAC (Multimodal-Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial by Solheim, Tora S, Laird, Barry J A, Balstad, Trude R, Bye, Asta, Stene, Guro, Baracos, Vickie, Strasser, Florian, Griffiths, Gareth, Maddocks, Matthew, Fallon, Marie, Kaasa, Stein, Fearon, Kenneth

“…Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional…”
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The use of opioids in cancer patients with renal impairment—a systematic review by Sande, Tonje A., Laird, Barry J. A., Fallon, Marie T.

“…Purpose Opioids are recommended for moderate to severe cancer pain; however, in patients with cancer, impaired renal function can affect opioid metabolism. The…”
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A systematic review examining the relationship between cytokines and cachexia in incurable cancer by Paval, D. Robert, Patton, Rebekah, McDonald, James, Skipworth, Richard J.E., Gallagher, Iain J., Laird, Barry J.

“…Cancer cachexia is an unmet clinical need that affects more than 50% of patients with cancer. The systemic inflammatory response, which is mediated by a…”
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Comparison of the prognostic value of ECOG-PS, mGPS and BMI/WL: Implications for a clinically important framework in the assessment and treatment of advanced cancer by Dolan, Ross D., Daly, Louise, Sim, Wei M.J., Fallon, Marie, Ryan, Aoife, McMillan, Donald C., Laird, Barry J.

“…The systemic inflammatory response is associated with the loss of lean tissue, anorexia, weakness, fatigue and reduced survival in patients with advanced…”
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REVOLUTION (Routine EValuatiOn of people LivIng with caNcer)-Protocol for a prospective characterisation study of patients with incurable cancer by Patton, Rebekah, Cook, Jane, Haraldsdottir, Erna, Brown, Duncan, Dolan, Ross D, McMillan, Donald C, Skipworth, Richard J E, Fallon, Marie, Laird, Barry J A

“…There is a pressing need for a holistic characterisation of people with incurable cancer. In this group, where quality of life and improvement of symptoms are…”
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The Systemic Inflammatory Response and Its Relationship to Pain and Other Symptoms in Advanced Cancer by Laird, Barry J., McMillan, Donald C., Fayers, Peter, Fearon, Kenneth, Kaasa, Stein, Fallon, Marie T., Klepstad, Pål

“…Introduction. Inflammation has been identified as a hallmark of cancer and may be necessary for tumorgenesis and maintenance of the cancer state…”
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The relationship between frailty, nutritional status, co-morbidity, CT-body composition and systemic inflammation in patients with COVID-19 by McGovern, Josh, Al-Azzawi, Yassir, Kemp, Olivia, Moffitt, Peter, Richards, Conor, Dolan, Ross D, Laird, Barry J, McMillan, Donald C, Maguire, Donogh

“…Frailty, determined by the Canadian Study of Health and Aging-Clinical Frailty Scale (CFS), is strongly associated with clinical outcomes including mortality…”
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The relationship between the BMI‐adjusted weight loss grading system and quality of life in patients with incurable cancer by Daly, Louise, Dolan, Ross, Power, Derek, Ní Bhuachalla, Éadaoin, Sim, Wei, Fallon, Marie, Cushen, Samantha, Simmons, Claribel, McMillan, Donald C., Laird, Barry J., Ryan, Aoife

“…Background Weight loss (WL) has long been recognized as an important factor associated with reduced quality of life (QoL) and reduced survival in patients with…”
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Understanding Cancer Cachexia and Its Implications in Upper Gastrointestinal Cancers by Brown, Leo R., Laird, Barry J. A., Wigmore, Stephen J., Skipworth, Richard J. E.

“…Opinion statement Considerable advances in the investigation and management of oesophagogastric cancer have occurred over the last few decades. While the…”
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The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review by McGovern, Josh, Dolan, Ross D, Horgan, Paul G, Laird, Barry J, McMillan, Donald C

“…Frailty is a complex multifactorial syndrome characterised by a significant increase in vulnerability and worsened health outcomes. Despite a range of proposed…”
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Is Radiotherapy Useful for Treating Pain in Mesothelioma?: A Phase II Trial by MacLeod, Nicholas, Chalmers, Anthony, O'Rourke, Noelle, Moore, Karen, Sheridan, Jonathan, McMahon, Lynn, Bray, Caroline, Stobo, Jon, Price, Alan, Fallon, Marie, Laird, Barry J

“…Radiotherapy is often used to treat pain in malignant pleural mesothelioma (MPM), although there is limited evidence to support this. The aim of this trial was…”
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Oral Ketamine vs Placebo in Patients With Cancer-Related Neuropathic Pain: A Randomized Clinical Trial by Fallon, Marie T, Wilcock, Andrew, Kelly, Caroline A, Paul, James, Lewsley, Liz-Anne, Norrie, John, Laird, Barry J A

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Integration of palliative rehabilitation in cancer care: a multinational mixed method study by Stene, Guro Birgitte, Hauken, May Aasebø, Ahmedzai, Hilde Hjelmeland, Storvestre, Constance Gaard, Vervik, Skjalg Eirik, Bayly, Joanne, Caraceni, Augusto Tommaso, Costi, Stefania, Economos, Guillaume, Guldin, Mai-Britt, Laird, Barry J. A., Nottelmann, Lise, Maddocks, Matthew, Prevost, Andrew Toby, Romeyer, Julia, Oldervoll, Line Merethe

“…Abstract Background Incurable cancer is a major contributor to societal suffering and disability, and palliative rehabilitation is recommended to be integrated…”
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Pain, Depression, and Fatigue as a Symptom Cluster in Advanced Cancer by Laird, Barry J.A., MBChB, MRCGP, DRCOG, MD, Scott, Angela C., MBChB, MRCP, MRCGP, MD, Colvin, Lesley A., MBChB, BSc, FRCA, PhD, McKeon, Amy-Louise, MSc, Murray, Gordon D., FRSE, FFPH, FRCP(Ed), C Stat, PhD, Dip Math Stat, MA, Fearon, Kenneth C.H., MBChB, MD, FRCPS(Glas), FRCS(Ed), FRCS (Eng), Fallon, Marie T., MBChB, MD, MRCGP, FRCP(Ed), FRCP(Glas), DRCOG, DCH

“…Abstract Context Pain, depression, and fatigue are common symptoms in cancer populations. They often coexist and have been suggested as a specific symptom…”
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The prevalence and prognostic value of systemic inflammation in good performance status patients with advanced, inoperable non‐small cell lung cancer receiving palliative radiotherapy: Comparison of composite ratios and cumulative scores by McGovern, Josh, O'Rourke, Fraser, Will, Sarah, Nguyen, Hanh Thi Ngoc, Cranfield, Elise, Maseland, Charlotte, MacLeod, Nicholas, Maclay, John D., Laird, Barry J., Dolan, Ross D., McMillan, Donald C.

“…Introduction The present study sought to examine the relationships between systemic inflammatory composite ratios/cumulative scores, magnitude of systemic…”
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The Impact of Acute Systemic Inflammation Secondary to Oesophagectomy and Anastomotic Leak on Computed Tomography Body Composition Analyses by Brown, Leo R, Ramage, Michael I, Dolan, Ross D, Sayers, Judith, Bruce, Nikki, Dick, Lachlan, Sami, Sharukh, McMillan, Donald C, Laird, Barry J A, Wigmore, Stephen J, Skipworth, Richard J E

“…This study aimed to longitudinally assess CT body composition analyses in patients who experienced anastomotic leak post-oesophagectomy. Consecutive patients,…”
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Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series by Vagnildhaug, Ola Magne, Balstad, Trude R., Ottestad, Inger, Bye, Asta, Greil, Christine, Arends, Jann, Baracos, Vickie, Brown, Leo R., Dajani, Olav F., Dolan, Ross D., Fallon, Marie, Fraser, Eilidh, Grzyb, Aleksandra, Hjermstad, Marianne J., Jakobsen, Gunnhild, Kaasa, Stein, McDonald, James, Philips, Iain, Sayers, Judith, Simpson, Melanie R., Sousa, Mariana S., Skipworth, Richard J.E., Laird, Barry J.A., Solheim, Tora S.

“…There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when comparing interventions and their clinical…”
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Characterization of cancer-induced bone pain: an exploratory study by Laird, Barry J. A., Walley, John, Murray, Gordon D., Clausen, Eleanor, Colvin, Lesley A., Fallon, Marie T.

“…Purpose Cancer-induced bone pain (CIBP) is the commonest cause of pain in patients with cancer. Its association with increased morbidity combined with…”
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