Search Results - "Laimins, L"

Histone deacetylase 3 localizes to the plasma membrane and is a substrate of Src by LONGWORTH, M. S, LAIMINS, L. A

“…Histone deacetylases (HDACs) negatively regulate gene expression by removing acetyl groups from lysine residues present in histones and other proteins. Histone…”
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The E8E2C protein, a negative regulator of viral transcription and replication, is required for extrachromosomal maintenance of human papillomavirus type 31 in keratinocytes by Stubenrauch, F, Hummel, M, Iftner, T, Laimins, L A

“…The viral E2 protein is a major regulator of papillomavirus DNA replication. An important way to influence viral replication is through modulation of the…”
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The E8^E2C Protein, a Negative Regulator of Viral Transcription and Replication, Is Required for Extrachromosomal Maintenance of Human Papillomavirus Type 31 in Keratinocytes by Stubenrauch, F., Hummel, M., Iftner, T., Laimins, L. A.

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Inhibition of p53 DNA binding by human papillomavirus E6 proteins by LECHNER, M. S, LAIMINS, L. A

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Microarray Analysis Identifies Interferon-Inducible Genes and Stat-1 as Major Transcriptional Targets of Human Papillomavirus Type 31 by Chang, Y E, Laimins, L A

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Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes by HUMMEL, M, HUDSON, J. B, LAIMINS, L. A

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Human papillomavirus life cycle: active and latent phases by Stubenrauch, Frank, Laimins, Laimonis A.

“…Productive infection by human papillomaviruses (HPV) is dependent upon the differentiation of the host cell. Following entry into basal epithelial cells, HPV…”
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Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53 by Mack, David H, Vartikar, Jai, Pipas, James M, Laimins, Laimonis A

“…The p53 protein is apparently central to the development of human cancers because both alleles are often found to be mutated in different tumour types. In…”
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Telomerase Activation by Human Papillomavirus Type 16 E6 Protein: Induction of Human Telomerase Reverse Transcriptase Expression through Myc and GC-Rich Sp1 Binding Sites by Oh, S T, Kyo, S, Laimins, L A

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Biosynthesis of Human Papillomavirus from a Continuous Cell Line Upon Epithelial Differentiation by Meyers, Craig, Frattini, Mark G., Hudson, John B., Laimins, Laimonis A.

“…The study of the human pathogen papillomaviruses (HPVs) has been hampered by the inability to propagate the virus in tissue culture. The addition of…”
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Differentiation-Dependent Chromatin Rearrangement Coincides with Activation of Human Papillomavirus Type 31 Late Gene Expression by Peña, Loren del Mar, Laimins, Laimonis A.

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In vitro Synthesis of Oncogenic Human Papillomaviruses Requires Episomal Genomes for Differentiation-Dependent Late Expression by Frattini, Mark G., Lim, Hock B., Laimins, Laimonis A.

“…Human papillomavirus (HPV) types 16, 18, 31, and 51 are the etiologic agents of many anogenital cancers including those of the cervix. These ``high risk'' HPVs…”
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Cellular Changes Induced by Low-Risk Human Papillomavirus Type 11 in Keratinocytes That Stably Maintain Viral Episomes by Thomas, J T, Oh, S T, Terhune, S S, Laimins, L A

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Early Polyadenylation Signals of Human Papillomavirus Type 31 Negatively Regulate Capsid Gene Expression by Terhune, S S, Hubert, W G, Thomas, J T, Laimins, L A

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Human Papillomavirus Type 16 Alters Human Epithelial Cell Differentiation in vitro by McCance, Dennis J., Kopan, Raphael, Fuchs, Elaine, Laimins, Laimonis A.

“…Human papillomavirus (HPV) types 16, 18, 31, and 33 have been implicated as etiologic agents of cervical and penile cancer. Using a cell culture system for…”
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Initiation of DNA synthesis by human papillomavirus E7 oncoproteins is resistant to p21-mediated inhibition of cyclin E-cdk2 activity by Ruesch, M N, Laimins, L A

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Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation by BEDELL, M. A, HUDSON, J. B, GOLUB, T. R, TURYK, M. E, HOSKEN, M, WILBANKS, G. D, LAIMINS, L. A

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Binding of the Human Papillomavirus E1 Origin-Recognition Protein is Regulated Through Complex Formation with the E2 Enhancer-Binding Protein by Frattini, Mark G., Laimins, Laimonis A.

“…The papillomavirus E1 and E2 proteins form heteromeric complexes and individually bind specific sequences within the viral origin of replication. The mechanism…”
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Human Papillomavirus Type 31 Oncoproteins E6 and E7 Are Required for the Maintenance of Episomes during the Viral Life Cycle in Normal Human Keratinocytes by Thomas, Jennifer T., Hubert, Walter G., Ruesch, Margaret N., Laimins, Laimonis A.

“…The E6 and E7 oncoproteins of the high-risk human papillomavirus (HPV) types are able to immortalize human keratinocytes in vitro and likely contribute to the…”
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Human papillomavirus type 18 E7 protein requires intact Cys-X-X-Cys motifs for zinc binding, dimerization, and transformation but not for Rb binding by MCINTYRE, M. C, FRATTINI, M. G, GROSSMAN, S. R, LAIMINS, L. A

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