Search Results - "Lai, Zc"

SP1-induced lncRNA DUBR promotes stemness and oxaliplatin resistance of hepatocellular carcinoma via E2F1-CIP2A feedback by Liu, S, Bu, Xy, Kan, Anna, Luo, L, Xu, Yj, Chen, Hl, Lin, Xj, Lai, Zc, Wen, Ds, Huang, Lc, Shi, M

“…Oxaliplatin-based chemotherapy is widely used to treat advanced hepatocellular carcinoma (HCC), but many patients develop drug resistance that leads to tumor…”
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Control of Cell Proliferation and Apoptosis by Mob as Tumor Suppressor, Mats by Lai, Zhi-Chun, Wei, Xiaomu, Shimizu, Takeshi, Ramos, Edward, Rohrbaugh, Margaret, Nikolaidis, Nikolas, Ho, Li-Lun, Li, Ying

“…Appropriate cell number and organ size in a multicellular organism are determined by coordinated cell growth, proliferation, and apoptosis. Disruption of these…”
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A Large-Scale Structural Classification of Antimicrobial Peptides by Lai, Jim Z. C., Yang, Je-Ruei, Lee, Chen-Che, Lee, Hao-Ting, Chang, Kuan Y.

“…Antimicrobial peptides (AMPs) are potent drug candidates against microbial organisms such as bacteria, fungi, parasites, and viruses. AMPs have abundant…”
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Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack by Li, S, Li, Y, Carthew, R W, Lai, Z C

“…The transcription repressor Tramtrack (TTK) is found in cone cells but not photoreceptor cells of the Drosophila eye. We show that down-regulation of TTK…”
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Notch Activation of yan Expression Is Antagonized by RTK/Pointed Signaling in the Drosophila Eye by Rohrbaugh, Margaret, Ramos, Edward, Nguyen, Duc, Price, Mitch, Wen, Yu, Lai, Zhi-Chun

“…Receptor tyrosine kinase (RTK) signaling plays an instructive role in cell fate decisions, whereas Notch signaling is often involved in restricting cellular…”
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Friction characterization and compensation of a linear-motor rolling-guide stage by Chen, J.-S., Chen, K.-C., Lai, Z.-C., Huang, Y.-K.

“…In this article, characterization and compensation for the friction at the micro (plastic module and nonlinear spring) and macro modes (nonlinear Coulomb and…”
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Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein by Lai, Z C, Rubin, G M

“…Loss-of-function mutations in the yan gene result in the differentiation of supernumerary photoreceptors in the Drosophila eye. The yan gene encodes a protein…”
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Scabrous and Gp150 are endosomal proteins that regulate Notch activity by Li, Yanxia, Fetchko, Michael, Lai, Zhi-Chun, Baker, Nicholas E

“…Notch and Delta are required for lateral inhibition during eye development. They prevent a tenfold excess in R8 photoreceptor cell specification. Mutations in…”
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Scabrous and Gp150 are endosomal proteins that regulate Notch activity

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The N-terminal BTB/POZ Domain and C-Terminal Sequences Are Essential for Tramtrack69 to Specify Cell Fate in the Developing Drosophila Eye by Wen, Yu, Nguyen, Duc, Li, Ying, Lai, Zhi-Chun

“…The BTB/POZ (broad complex Tramtrack bric-a-brac/Pox virus and zinc finger) domain is an evolutionarily conserved protein-protein interaction motif. Many…”
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Executive system dysfunction in the aged monkey: Spatial and object reversal learning by Lai, Zona C., Moss, Mark B., Killiany, Ronald J., Rosene, Douglas L., Herndon, James G.

“…As part of an effort to characterize age-related cognitive changes in executive system function in a nonhuman primate model of human aging, the performance of…”
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Two distantly positioned PDZ domains mediate multivalent INAD-phospholipase C interactions essential for G protein-coupled signaling by Huizen, R. van, Miller, K, Chen, D.M, Li, Y, Lai, Z.C, Raab, R.W, Stark, W.S, Shortride, R.D, Li, M

“…Drosophila INAD, which contains five tandem protein interaction PDZ domains, plays an important role in the G protein‐coupled visual signal transduction…”
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Evolution of functional diversification of the paired box (Pax) DNA-binding domains by Balczarek, K A, Lai, Z C, Kumar, S

“…The Pax gene family consists of tissue-specific transcriptional regulators that always contain a highly conserved DNA-binding domain with six alpha-helices…”
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Tramtrack69 is positively and autonomously required for drosophila photoreceptor development by Lai, Z.C, Li, Y

“…Cell-fate specification and cellular differentiation are tightly controlled by both positive and negative transcriptional factors during development. The…”
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Rough clustering using generalized fuzzy clustering algorithm by Lai, Jim Z.C., Juan, Eric Y.T., Lai, Franklin J.C.

“…In this paper, we present a rough k-means clustering algorithm based on minimizing the dissimilarity, which is defined in terms of the squared Euclidean…”
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Recognition memory span in rhesus monkeys of advanced age by Moss, Mark B., Killiany, Ronald J., Lai, Zona C., Rosene, Douglas L., Herndon, James G.

“…Assessment of recognition memory was performed on eight rhesus monkeys of advanced age (25 to 27 years of age) using the delayed recognition span test (DRST)…”
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Drosophila Gp150 is required for early ommatidial development through modulation of Notch signaling by Fetchko, Michael, Huang, Wei, Li, Ying, Lai, Zhi-Chun

“…Cellular signaling activities must be tightly regulated for proper cell fate control and tissue morphogenesis. Here we report that the Drosophila leucine‐rich…”
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An agglomerative clustering algorithm using a dynamic k-nearest-neighbor list by Lai, Jim Z.C., Huang, Tsung-Jen

“…In this paper, a new algorithm is developed to reduce the computational complexity of Ward’s method. The proposed approach uses a dynamic k-nearest-neighbor…”
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Shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene by Treisman, J E, Lai, Z C, Rubin, G M

“…Differentiation in the Drosophila eye imaginal disc traverses the disc as a wave moving from posterior to anterior. The propagation of this wave is driven by…”
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Identifying functional cis-acting regulatory modules of the yan gene in Drosophila melanogaster by Ramos, Edward, Price, Mitch, Rohrbaugh, Margaret, Lai, Zhi-Chun

“…Yan is a nuclear DNA-binding protein that acts as a general inhibitor of cellular differentiation and proliferation in Drosophila melanogaster. The genetic and…”
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