Search Results - "Lai, Weifeng"

Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State by Li, Xiang, Liu, Defang, Ma, Yantao, Du, Xiaomin, Jing, Junzhan, Wang, Lipeng, Xie, Bingqing, Sun, Da, Sun, Shaoqiang, Jin, Xueqin, Zhang, Xu, Zhao, Ting, Guan, Jingyang, Yi, Zexuan, Lai, Weifeng, Zheng, Ping, Huang, Zhuo, Chang, Yanzhong, Chai, Zhen, Xu, Jun, Deng, Hongkui

“…Direct lineage reprogramming, including with small molecules, has emerged as a promising approach for generating desired cell types. We recently found that…”
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Chemically defined and xeno-free culture condition for human extended pluripotent stem cells by Liu, Bei, Chen, Shi, Xu, Yaxing, Lyu, Yulin, Wang, Jinlin, Du, Yuanyuan, Sun, Yongcheng, Liu, Heming, Zhou, Haoying, Lai, Weifeng, Xue, Anqi, Yin, Ming, Li, Cheng, Bai, Yun, Xu, Jun, Deng, Hongkui

“…Extended pluripotent stem (EPS) cells have shown great applicative potentials in generating synthetic embryos, directed differentiation and disease modeling…”
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A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts by Xie, Bingqing, Sun, Da, Du, Yuanyuan, Jia, Jun, Sun, Shicheng, Xu, Jun, Liu, Yifang, Xiang, Chengang, Chen, Sitong, Xie, Huangfan, Wang, Qiming, Li, Guangya, LYU, Xuehui, Shen, Hui, Li, Shiyu, Wu, Min, Zhang, Xiaonan, Pu, Yue, Xiang, Kuanhui, Lai, Weifeng, Du, Peng, Yuan, Zhenghong, Li, Cheng, Shi, Yan, Lu, Shichun, Deng, Hongkui

“…Terminally differentiated cells can be generated by lineage reprogramming, which is, however, hindered by incomplete conversion with residual initial cell…”
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Chemical reprogramming of human somatic cells to pluripotent stem cells by Guan, Jingyang, Wang, Guan, Wang, Jinlin, Zhang, Zhengyuan, Fu, Yao, Cheng, Lin, Meng, Gaofan, Lyu, Yulin, Zhu, Jialiang, Li, Yanqin, Wang, Yanglu, Liuyang, Shijia, Liu, Bei, Yang, Zirun, He, Huanjing, Zhong, Xinxing, Chen, Qijing, Zhang, Xu, Sun, Shicheng, Lai, Weifeng, Shi, Yan, Liu, Lulu, Wang, Lipeng, Li, Cheng, Lu, Shichun, Deng, Hongkui

“…Cellular reprogramming can manipulate the identity of cells to generate the desired cell types 1 – 3 . The use of cell intrinsic components, including oocyte…”
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CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo by Xu, Lei, Yang, Huan, Gao, Yang, Chen, Zeyu, Xie, Liangfu, Liu, Yulin, Liu, Ying, Wang, Xiaobao, Li, Hanwei, Lai, Weifeng, He, Yuan, Yao, Anzhi, Ma, Liying, Shao, Yiming, Zhang, Bin, Wang, Chengyan, Chen, Hu, Deng, Hongkui

“…Transplantation of hematopoietic stem cells (HSCs) with a naturally occurring CCR5 mutation confers a loss of detectable HIV-1 in the patient, making ablation…”
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Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency by Yang, Yang, Liu, Bei, Xu, Jun, Wang, Jinlin, Wu, Jun, Shi, Cheng, Xu, Yaxing, Dong, Jiebin, Wang, Chengyan, Lai, Weifeng, Zhu, Jialiang, Xiong, Liang, Zhu, Dicong, Li, Xiang, Yang, Weifeng, Yamauchi, Takayoshi, Sugawara, Atsushi, Li, Zhongwei, Sun, Fangyuan, Li, Xiangyun, Li, Chen, He, Aibin, Du, Yaqin, Wang, Ting, Zhao, Chaoran, Li, Haibo, Chi, Xiaochun, Zhang, Hongquan, Liu, Yifang, Li, Cheng, Duo, Shuguang, Yin, Ming, Shen, Huan, Belmonte, Juan Carlos Izpisua, Deng, Hongkui

“…Of all known cultured stem cell types, pluripotent stem cells (PSCs) sit atop the landscape of developmental potency and are characterized by their ability to…”
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Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity by Li, Yuanjun, Huang, Jie, Zhu, Junyi, Bao, Lijun, Wang, Hui, Jiang, Yongpeng, Tian, Kai, Wang, Rui, Zheng, Haonan, Duan, WenJia, Lai, Weifeng, Yi, Xiao, Zhu, Yi, Guo, Tiannan, Ji, Xiong

“…RNA polymerase II (RNA Pol II) subunits are thought to be involved in various transcription-associated processes, but it is unclear whether they play different…”
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Drug sensitivity profiling identifies potential therapies for myeloid neoplasm with eosinophilia driven by a novel G3BP1-PDGFRB fusion gene by Wang, Jianli, Xu, Lei, Li, Yuqing, Wang, Jun, Shao, Yangliu, Lai, Weifeng, Yong, Jun, Zhao, Ling, Wei, Xuemin, Gao, Chunji, Liu, Daihong, Gao, Xiaoning, Zhang, Yongqing

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Human pluripotent stem cell-derived eosinophils reveal potent cytotoxicity against solid tumors by Lai, Weifeng, Xie, Huangfan, Liu, Yuting, Zheng, Feng, Zhang, Yingfeng, Lei, Qi, Lv, Lejun, Dong, Jiebin, Song, Jian, Gao, Xue, Yin, Ming, Wang, Chengyan, Deng, Hongkui

“…Eosinophils are attractive innate immune cells to use to potentiate T cell antitumor efficacy because they are capable of infiltrating tumors at early stages…”
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Targeting JNK pathway promotes human hematopoietic stem cell expansion by Xiao, Xiong, Lai, Weifeng, Xie, Huangfan, Liu, Yang, Guo, Weijie, Liu, Yifang, Li, Yu, Li, Yuanjun, Zhang, Jingliang, Chen, Wenhan, Shi, Minhui, Shang, Lijun, Yin, Ming, Wang, Chengyan, Deng, Hongkui

“…The limited number of human hematopoietic stem cells (HSCs) has restrained their widespread clinical application. Despite great efforts in recent years, the in…”
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Identification and characterization of the Oct4 extended transcriptional regulatory region in Guanzhong dairy goat by Cheng, Xiang, Meng, Shuyan, Deng, Jie, Lai, Weifeng, Wang, Huayan

“…The octamer-binding transcription factor 4 gene (Oct4) plays a critical role in maintaining pluripotency during early mammalian embryonic development and…”
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