Search Results - "Lai, Sizhen"

An novel effective and safe model for the diagnosis of nonalcoholic fatty liver disease in China: gene excavations, clinical validations, and mechanism elucidation by Wang, Jida, Jia, Beitian, Miao, Jing, Li, Dun, Wang, Yin, Han, Lu, Yuan, Yin, Zhang, Yuan, Wang, Yiyang, Guo, Liying, Jia, Jianwei, Zheng, Fang, Lai, Sizhen, Niu, Kaijun, Li, Weidong, Bian, Yuhong, Wang, Yaogang

“…Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases. NAFLD leads to liver fibrosis and hepatocellular carcinoma, and it…”
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FTO promotes colorectal cancer progression and chemotherapy resistance via demethylating G6PD/PARP1 by Wang, Jiyan, Qiao, Yaya, Sun, Mingming, Sun, Huanran, Xie, Fei, Chang, Hongkai, Wang, Yingzhi, Song, Jiaqi, Lai, Sizhen, Yang, Chenxin, Li, Xichuan, Liu, Shuangping, Zhao, Xuanzhu, Ni, Kemin, Meng, Kewei, Zhang, Shuai, Shan, Changliang, Zhang, Chunze

“…SEE PDF] G6PD, as first key enzyme of pentose phosphate pathway (PPP), is main producer of NADPH.4 PARP1 plays an indispensable role in DNA damage repair,…”
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PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism by Sun, Mingming, Li, Leilei, Niu, Yujia, Wang, Yingzhi, Yan, Qi, Xie, Fei, Qiao, Yaya, Song, Jiaqi, Sun, Huanran, Li, Zhen, Lai, Sizhen, Chang, Hongkai, Zhang, Han, Wang, Jiyan, Yang, Chenxin, Zhao, Huifang, Tan, Junzhen, Li, Yanping, Liu, Shuangping, Lu, Bin, Liu, Min, Kong, Guangyao, Zhao, Yujun, Zhang, Chunze, Lin, Shu-Hai, Luo, Cheng, Zhang, Shuai, Shan, Changliang

“…Metabolic reprogramming is a hallmark of cancer, including lung cancer. However, the exact underlying mechanism and therapeutic potential are largely unknown…”
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Clinicopathological and prognostic value of SIRT6 in patients with solid tumors: a meta-analysis and TCGA data review by Wu, Xiaojing, Wang, Shuyuan, Zhao, Xuanzhu, Lai, Sizhen, Yuan, Zhen, Zhan, Yixiang, Ni, Kemin, Liu, Zhaoce, Liu, Lina, Xin, Ran, Zhou, Xingyu, Yin, Xin, Liu, Xinyu, Zhang, Xipeng, Cui, Wei, Zhang, Chunze

“…In addition to its role in cellular progression and cancer, SIRT6, a member of nicotinamide adenine dinucleotide (NAD )-dependent class III deacylase sirtuin…”
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Connexin 43 contributes to the sensitization of colorectal cancer cells to photodynamic therapy through Akt inhibition by Wang, Yijia, Chen, Lankai, Lai, Sizhen, Liu, Yanfei, Yi, Ben, Zhu, Siwei, Hu, Xia, Zhang, Qinghuai, Zhang, Chunze

“…•Akt activation is a cellular survival response to photodynamic therapy.•Akt interacts with connexin 43 during photodynamic therapy.•Connexin 43 sensitizes…”
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Young Patients With Colorectal Cancer Have Higher Early Mortality but Better Long-Term Survival by Wang, Shuyuan, Yuan, Zhen, Ni, Kemin, Zhan, Yixiang, Zhao, Xuanzhu, Liu, Zhaoce, Liu, Yanfei, Yi, Ben, Lai, Sizhen, Yin, Xin, Zhou, Xingyu, Wang, Yuqi, Ping, Hangyu, Xin, Ran, Wang, Wenhong, Li, Hongzhou, Zhao, Yuanshun, Han, Youkui, Gao, Weifeng, Jin, Xinlei, Wang, Guihua, Zhang, Zili, Li, Guoxun, Zhang, Qinghuai, Zhang, Xipeng, Ma, Hong, Zhang, Chunze

“…To define the prognosis of colorectal cancer (CRC) in young patients and to compare their postoperative treatment with that of older patients. This multicenter…”
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