Search Results - "Lai, Ruixue"
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The SNPs of mitochondrial DNA displacement loop region and mitochondrial DNA copy number associated with risk of polymyositis and dermatomyositis
Published in Scientific reports (07-04-2022)“…Oxidative damage-induced mitochondrial dysfunction may activate muscle catabolism and autophagy pathways to initiate muscle weakening in idiopathic…”
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Correlation Between Immune-Related Adverse Events and Prognosis in Hepatocellular Carcinoma Patients Treated With Immune Checkpoint Inhibitors
Published in Frontiers in immunology (07-12-2021)“…Immune-related adverse events (irAEs) caused by immune checkpoint inhibitors (ICIs) were associated with clinical benefit in cancer patients of melanoma, a…”
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Are anti-PD-1-associated immune related adverse events a harbinger of favorable clinical prognosis in patients with gastric cancer?
Published in BMC cancer (05-11-2022)“…Background Immune checkpoint inhibitors (ICIs) has shown remarkable benefit in the treatment of a range of cancer types, although it may initiate immune…”
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Mitochondrial Displacement Loop Region SNPs Modify Sjögren's Syndrome Development by Regulating Cytokines Expression in Female Patients
Published in Frontiers in genetics (11-03-2022)“…Mitochondrial dysfunction could induce innate immune response with cytokines releasing to initiate Sjögren's syndrome (SS) onset. Single nucleotide…”
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Dicer Suppresses Hepatocellular Carcinoma via Interleukin-8 Pathway
Published in Clinical Medicine Insights. Oncology (01-01-2023)“…Background: Elevated level of interleukin-8 (IL-8) promotes hepatocellular carcinoma (HCC) development and contributes to poor prognosis. Previously, we have…”
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Negative impact of antibiotic administration on the clinical activity in patients with advanced gastric cancer
Published in Biotechnology, biotechnological equipment (01-01-2021)“…Antibiotics (ATBs) induce dysbiosis of the gut microbiota by altering the diversity and composition of the microbiota, which mediates the efficacy and toxicity…”
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Type I collagen promotes tumor progression of integrin β1 positive gastric cancer through a BCL9L/β-catenin signaling pathway
Published in Aging (Albany, NY.) (28-07-2021)“…The mechanism of extracellular matrix induced tumor progression is poorly understood. Based on the TCGA database and clinical tumor tissues analysis, we…”
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Risk‐associated single nucleotide polymorphisms of mitochondrial D‐loop mediate imbalance of cytokines and redox in rheumatoid arthritis
Published in International journal of rheumatic diseases (01-01-2023)“…Background We have identified rheumatoid arthritis (RA) risk‐associated single nucleotide polymorphisms (SNPs) in the mitochondrial displacement loop (D‐loop)…”
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Identification of sequence polymorphisms in the mitochondrial deoxyribonucleic acid displacement-loop region as risk factors for systemic lupus erythematosus
Published in Archives of rheumatology (01-09-2021)“…Objectives: This study aims to evaluate the relationship between sequence polymorphisms (SNPs) in the displacement-loop (D-loop) region of mitochondrial…”
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Nonsynonymous C1653T Mutation of Hepatitis B Virus X Gene Enhances Malignancy of Hepatocellular Carcinoma Cells
Published in Journal of hepatocellular carcinoma (01-01-2022)“…Functional analysis was performed to elucidate the mechanism by which hepatocellular carcinoma (HCC) outcome-associated mutation in the hepatitis B virus X ( )…”
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Ischemic colitis caused by polycythemia vera: A case report and literature review
Published in Experimental and therapeutic medicine (01-10-2018)“…Polycythemia vera (PV) is a chronic myeloproliferative disorder originating from hematopoietic stem cells and complicated by thrombosis and bleeding. This…”
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Antibiotics Modulate Chemotherapy Efficacy in Patients with Esophageal Cancer
Published in Cancer management and research (01-01-2020)“…Accumulating evidence suggests that microbiota dysbiosis induced by antibiotic administration plays a crucial role in regulating the efficacy and toxicity of…”
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