Search Results - "Lai, Pei F"

Progesterone-Related Immune Modulation of Pregnancy and Labor by Shah, Nishel M, Lai, Pei F, Imami, Nesrina, Johnson, Mark R

“…Pregnancy involves a complex interplay between maternal neuroendocrine and immunological systems in order to establish and sustain a growing fetus. It is…”
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Myometrial Transcriptional Signatures of Human Parturition by Stanfield, Zachary, Lai, Pei F, Lei, Kaiyu, Johnson, Mark R, Blanks, Andrew M, Romero, Roberto, Chance, Mark R, Mesiano, Sam, Koyutürk, Mehmet

“…The process of parturition involves the transformation of the quiescent myometrium (uterine smooth muscle) to the highly contractile laboring state. This is…”
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Labour classified by cervical dilatation & fetal membrane rupture demonstrates differential impact on RNA-seq data for human myometrium tissues by Lai, Pei F, Lei, Kaiyu, Zhan, Xiaoyu, Sooranna, Gavin, Li, Jonathan K H, Georgiou, Ektoras X, Das, Ananya, Singh, Natasha, Li, Qiye, Stanfield, Zachary, Zhang, Guojie, Tribe, Rachel M, Mesiano, Sam, Johnson, Mark R

“…High throughput sequencing has previously identified differentially expressed genes (DEGs) and enriched signalling networks in human myometrium for term (≥37…”
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Evaluating aminophylline and progesterone combination treatment to modulate contractility and labor‐related proteins in pregnant human myometrial tissues by Lai, Pei F., Young, Roger C., Tribe, Rachel M., Johnson, Mark R.

“…Progesterone (P4) and cyclic adenosine monophosphate (cAMP) are regarded as pro‐quiescent factors that suppress uterine contractions during pregnancy. We…”
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Corrigendum: Myometrial Transcriptional Signatures of Human Parturition by Stanfield, Zachary, Lai, Pei F, Lei, Kaiyu, Johnson, Mark R, Blanks, Andrew M, Romero, Roberto, Chance, Mark R, Mesiano, Sam, Koyutürk, Mehmet

“…[This corrects the article DOI: 10.3389/fgene.2019.00185.]…”
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Tetrabromobisphenol A (TBBPA), induces cell death in TM4 Sertoli cells by modulating Ca2+ transport proteins and causing dysregulation of Ca2+ homeostasis by Ogunbayo, Oluseye A., Lai, Pei F., Connolly, Thomas J., Michelangeli, Francesco

“…Tetrabromobisphenol A (TBBPA) is a commonly used brominated flame retardant (BFR) utilized to reduce the flammability of a variety of products. Studies have…”
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Aminophylline and progesterone prevent inflammation-induced preterm parturition in the mouse by Herbert, Bronwen R, Markovic, Danijela, Georgiou, Ektoras, Lai, Pei F, Singh, Natasha, Yulia, Angela, Johnson, Mark R

“…Although progesterone (P4) supplementation is the most widely used therapy for the prevention of preterm labor (PTL), reports of its clinical efficacy have…”
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Differential impact of acute and prolonged cAMP agonist exposure on protein kinase A activation and human myometrium contractile activity by Lai, Pei F., Tribe, Rachel M., Johnson, Mark R.

“…Key points Over 15 million babies are born prematurely each year with approximately 1 million of these babies dying as a direct result of preterm delivery…”
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Transcription factors regulated by cAMP in smooth muscle of the myometrium at human parturition by Li, Jonathan K H, Lai, Pei F, Tribe, Rachel M, Johnson, Mark R

“…Cyclic adenosine monophosphate (cAMP) contributes to maintenance of a quiescent (relaxed) state in the myometrium (i.e. uterine smooth muscle) during…”
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Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology by Huang, Zhengyuan, Lai, Pei F, Cocker, Alexander T H, Haslam, Stuart M, Dell, Anne, Brady, Hugh J M, Johnson, Mark R

“…Protein N-linked glycosylation is a structurally diverse post-translational modification that stores biological information in a larger order of magnitude than…”
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The impact of progesterone and RU-486 on classic pro-labour proteins & contractility in human myometrial tissues during 24-hour exposure to tension & interleukin-1β by Lai, Pei F., Georgiou, Ektoras X., Tribe, Rachel M., Johnson, Mark R.

“…Increased expression of pro-labour genes that encode cyclooxygenase-2 (COX-2), oxytocin receptor (OTR) and connexin-43 (Cx43) at parturition is often…”
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Targeting an Initiator Allergen Provides Durable and Expansive Protection against House Dust Mite Allergy by Zhang, Jihui, Chen, Jie, Richardson, Jonathan P., Francis-Newton, Nicola-Jane, Lai, Pei F., Jenkins, Kerry, Major, Meriel R., Key, Rebekah E., Stewart, Mark E., Firth-Clark, Stuart, Lloyd, Steven M., Newton, Gary K., Perrior, Trevor R., Garrod, David R., Robinson, Clive

“…Whereas treatment of allergic diseases such as asthma relies largely on the targeting of dysregulated effector pathways, the conceptually attractive…”
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Isolation of single cells from human uterus in the third trimester of pregnancy: myometrium, decidua, amnion and chorion by Cocker, Alexander T H, Whettlock, Emily M, Browne, Brendan, Lai, Pei F, Li, Jonathan K H, Sivarajasingam, Sivatharjini P, Imami, Nesrina, Johnson, Mark R, Male, Victoria

“…During pregnancy, interactions between uterine immune cells and cells of the surrounding reproductive tissues are thought to be vital for regulating labour…”
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Endocrine disrupting alkylphenols: structural requirements for their adverse effects on Ca2+ pumps, Ca2+ homeostasis & Sertoli TM4 cell viability by Michelangeli, Francesco, Ogunbayo, Oluseye A, Wootton, Laura L, Lai, Pei F, Al-Mousa, Fawaz, Harris, Robert M, Waring, Rosemary H, Kirk, Christopher J

“…Alkylphenols such as nonylphenol are pollutants that are widely dispersed within our environment. They bio-accumulate within man, with levels in the muM…”
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Labour classified by cervical dilatation fetal membrane rupture demonstrates differential impact on RNA-seq data for human myometrium tissues by Pei F Lai, Kaiyu Lei, Xiaoyu Zhan, Gavin Sooranna, Jonathan K H Li, Ektoras X Georgiou, Ananya Das, Natasha Singh, Qiye Li, Zachary Stanfield, Guojie Zhang, Rachel M Tribe, Sam Mesiano, Mark R Johnson

“…High throughput sequencing has previously identified differentially expressed genes (DEGs) and enriched signalling networks in human myometrium for term (≥37…”
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Endocrine disrupting alkylphenols: Structural requirements for their adverse effects on Ca super(2+)pumps, Ca super(2+) homeostasis & Sertoli TM4 cell viability by Michelangeli, Francesco, Ogunbayo, Oluseye A, Wootton, Laura L, Lai, Pei F, Al-Mousa, Fawaz, Harris, Robert M, Waring, Rosemary H, Kirk, Christopher J

“…Alkylphenols such as nonylphenol are pollutants that are widely dispersed within our environment. They bio-accumulate within man, with levels in the kM…”
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Endocrine disrupting alkylphenols: Structural requirements for their adverse effects on Ca 2+pumps, Ca 2+ homeostasis & Sertoli TM4 cell viability by Michelangeli, Francesco, Ogunbayo, Oluseye A., Wootton, Laura L., Lai, Pei F., Al-Mousa, Fawaz, Harris, Robert M., Waring, Rosemary H., Kirk, Christopher J.

“…Alkylphenols such as nonylphenol are pollutants that are widely dispersed within our environment. They bio-accumulate within man, with levels in the μM…”
Get full text