Search Results - "Lai, P. B."

Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services by Søreide, K, Hallet, J, Matthews, J B, Schnitzbauer, A A, Line, P D, Lai, P B S, Otero, J, Callegaro, D, Warner, S G, Baxter, N N, Teh, C S C, Ng-Kamstra, J, Meara, J G, Hagander, L, Lorenzon, L

“…Abstract Background The ongoing pandemic is having a collateral health effect on delivery of surgical care to millions of patients. Very little is known about…”
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Meta‐analysis: the efficacy of anti‐viral therapy in prevention of recurrence after curative treatment of chronic hepatitis B‐related hepatocellular carcinoma by Wong, J. S.‐W., Wong, G. L.‐H., Tsoi, K. K.‐F., Wong, V. W.‐S., Cheung, S. Y.‐S., Chong, C.‐N., Wong, J., Lee, K.‐F., Lai, P. B.‐S., Chan, H. L.‐Y.

“…Aliment Pharmacol Ther 2011; 33: 1104–1112 Summary Background  The role of anti‐viral therapy in prevention of hepatocellular carcinoma (HCC) recurrence is to…”
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HBx mutants differentially affect the activation of hypoxia-inducible factor-1α in hepatocellular carcinoma by Liu, L-p, Hu, B-g, Ye, C, Ho, R L K, Chen, G G, Lai, P B S

“…Background: Mutations in HBx gene are frequently found in HBV-associated hepatocellular carcinoma (HCC). Activation of hypoxia-inducible factor-1 α (HIF-1 α )…”
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Randomized clinical trial of open hepatectomy with or without intermittent Pringle manoeuvre by Lee, K. F., Cheung, Y. S., Wong, J., Chong, C. C., Wong, J. S., Lai, P. B.

“…Background: The intermittent Pringle manoeuvre (IPM) is commonly applied during liver resection. Few randomized trials have addressed its effectiveness in…”
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The analgesic efficacy of continuous wound instillation with ropivacaine after open hepatic surgery by Chan, S. K., Lai, P. B., Li, P. T., Wong, J., Karmakar, M. K., Lee, K. F., Gin, T.

“…Summary The analgesic efficacy of continuous local anaesthetic wound instillation after open hepatic surgery was evaluated. Forty‐eight patients scheduled for…”
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Quality of life is predictive of survival in patients with unresectable hepatocellular carcinoma by Yeo, W., Mo, F.K.F., Koh, J., Chan, A.T.C., Leung, T., Hui, P., Chan, L., Tang, A., Lee, J.J., Mok, T.S.K., Lai, P.B.S., Johnson, P.J., Zee, B.

“…Background: Patients with unresectable hepatocellular carcinoma (HCC) have a dismal prognosis. The objective of this study was to evaluate whether…”
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Increased expression of nucleophosmin B23 in hepatocellular carcinoma and correlation with clinicopathological parameters by YUN, J.-P, MIAO, J, CHEN, G. G, TIAN, Q.-H, ZHANG, C.-Q, XIANG, J, FUL, J, LAI, P. B. S

“…Nucleophosmin (NPM, B23, numatrin, NO38) is an abundant nucleolar phosphoprotein involved in multiple cellular functions. Previous evidence indicates that…”
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Antiviral therapy after curative resection for patients with hepatitis B-related hepatocellular carcinoma by Chong, C. C. N., Lai, P. B. S.

“…Merits evaluation in the West…”
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Bid stands at the crossroad of stress-response pathways by Song, G, Chen, G G, Hu, T, Lai, P B S

“…Bid, a BH3-only Bcl-2 family member, is proven to be a pivotal molecule for the regulation of tumorigenesis by its multiple functions in promoting apoptosis,…”
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Therapeutic effect of α-fetoprotein promoter-mediated tBid and chemotherapeutic agents on orthotopic liver tumor in mice by Ma, S-H, Chen, G G, Yip, J, Lai, P B S

“…Previous studies have shown that the application of Ad/AFPtBid significantly and specifically killed hepatocellular carcinoma (HCC) cells in culture and…”
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Randomized trial of early versus delayed laparoscopic cholecystectomy for acute cholecystitis by Lai, P. B. S., Kwong, K. H., Leung, K. L., Kwok, S. P. Y., Chan, A. C. W., Chung, S. C. S., Lau, W. Y.

“…Background The aim of this prospective randomized study was to define the optimum management between early and delayed laparoscopic cholecystectomy for…”
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BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma by Chan, B C-L, Ching, A K-K, To, K-F, Leung, J C-K, Chen, S, Li, Q, Lai, P B-S, Tang, N L-S, Shaw, P-C, Chan, J Y-H, James, A E, Lai, K-N, Lim, P-L, Lee, K K-H, Chui, Y-L

“…BRE binds to the cytoplasmic domains of tumor necrosis factor receptor-1 and Fas, and in cell lines can attenuate death receptor-initiated apoptosis by…”
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Clinical significance of CDX2-positive circulating tumour cells in colorectal cancer patients by Wong, S C C, Ng, S S M, Cheung, M T, Luk, L Y, Chan, C M L, Cheung, A H K, Lee, V H M, Lai, P B S, Ma, B B Y, Hui, E P, Lam, M Y Y, Au, T C C, Chan, A T C

“…Background: Our recent work has shown the feasibility of using a refined immunomagnetic enrichment (IE) assay to detect cytokeratin 20-positive circulating…”
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5-(Dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide as a novel bifunctional antitumor agent and two-photon induced bio-imaging probe by Chui, C-H, Wang, Q, Chow, W-C, Yuen, M C-W, Wong, K-L, Kwok, W-M, Cheng, G Y-M, Wong, R S-M, Tong, S-W, Chan, K-W, Lau, F-Y, Lai, P B-S, Lam, K-H, Fabbri, E, Tao, X-M, Gambari, R, Wong, W-Y

“…A novel compound, (5-(dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide), was prepared and characterized; it shows dual functional roles as an…”
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Preoperative serum α-fetoprotein and prognosis after hepatectomy for hepatocellular carcinoma by Yang, S.-L., Liu, L.-P., Yang, S., Liu, L., Ren, J.-W., Fang, X., Chen, G. G., Lai, P. B. S.

“…Background While the majority of studies report that a raised serum α‐fetoprotein (AFP) level before operation is associated with a high risk of recurrence and…”
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Routine early laparoscopic cholecystectomy for acute cholecystitis after conclusion of a randomized controlled trial by Teoh, A. Y. B., Chong, C. N., Wong, J., Lee, K. F., Chiu, P. W. Y., Ng, S. S. M., Lai, P. B. S.

“…Background: The aim of this retrospective review was to assess the clinical outcomes of laparoscopic cholecystectomy for acute cholecystitis since the…”
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Cumulative effects of pre-pandemic vulnerabilities and pandemic-related hardship on psychological distress among pregnant individuals by Giesbrecht, G.F., van de Wouw, M., Rioux, C., Lai, B.P.Y., King, S., Tomfohr-Madsen, L., Lebel, C.

“…Our primary objective was to determine whether pre-existing vulnerabilities and resilience factors combined with objective hardship resulted in cumulative…”
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Selection of patients for laparoscopic repair of perforated peptic ulcer by Lee, F. Y. J., Leung, K. L., Lai, P. B. S., Lau, J. W. Y.

“…Background: Although randomized and non‐randomized studies have evaluated the safety of laparoscopic repair for perforated peptic ulcer, no definite guidelines…”
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Effect of local injection of mesenchymal stem cells on healing of sutured gastric perforation in an experimental model by Liu, L., Chiu, P. W. Y., Lam, P. K., Poon, C. C. Y., Lam, C. C. H., Ng, E. K. W., Lai, P. B. S.

“…Background Mesenchymal stem cells are proposed to facilitate repair of organ injuries. The aim of this study was to investigate whether local injection of…”
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Antiviral therapy improves post‐hepatectomy survival in patients with hepatitis B virus‐related hepatocellular carcinoma: a prospective‐retrospective study by Chong, C. C. N., Wong, G. L. H., Wong, V. W. S., Ip, P. C. T., Cheung, Y. S., Wong, J., Lee, K. F., Lai, P. B. S., Chan, H. L. Y.

“…Summary Background The effect of antiviral therapy on the post‐hepatectomy long‐term survival in patients with hepatitis B virus (HBV)‐related hepatocellular…”
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