Search Results - "Lai, Mingyao"
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Intracranial management of HER-2 overexpression breast cancer with extensive volume or symptomatic brain metastases
Published in Frontiers in oncology (01-07-2024)“…This study aimed to evaluate the impact of high intracranial burden and symptomatic presentation of brain metastases on treatment outcomes in patients with…”
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2
Stroke as initial manifestation of non-small cell lung cancer with Trousseau syndrome
Published in BMC cancer (10-11-2023)“…Abstract Objective Stroke is a rare but fatal complication of advanced cancer with Trousseau syndrome, especially as initial symptoms. Here, we report the…”
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3
Increased M1 Macrophages Infiltration Correlated With Poor Survival Outcomes and Radiation Response in Gliomas
Published in Dose-response (01-10-2020)“…Background: Gliomas are the malignance of a poor prognosis. The current WHO classification remains unable to predict survival outcomes accurately. Novel…”
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4
Whole brain radiotherapy (WBRT) for leptomeningeal metastasis from NSCLC in the era of targeted therapy: a retrospective study
Published in Radiation oncology (London, England) (31-07-2020)“…Abstract Background and purpose Leptomeningeal metastasis (LM) is a rare but detrimental complication in patients with non-small cell lung cancer (NSCLC)…”
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Case Report: Clinicopathological and Genetic Features of IDH-Mutant Brainstem Glioma in Adults: Report of Five Cases
Published in Pathology oncology research (04-08-2022)“…Adult brainstem gliomas are rare central nervous system tumors that represent a heterogeneous group of tumors. Somatic IDH mutations are uncommon in adult…”
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Efficacy and safety of osimertinib for leptomeningeal metastases from EGFR-mutant non-small cell lung cancer: a pooled analysis
Published in European journal of medical research (04-08-2023)“…The aim of this study was to evaluate the efficacy and safety of osimertinib for the treatment of leptomeningeal metastases (LM) from epidermal growth factor…”
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Survival outcomes, hematologic complications and growth impairment after sequential chemoradiotherapy in intracranial NGGCTs: a retrospective study
Published in Strahlentherapie und Onkologie (01-05-2022)“…Purpose This study aimed to evaluate the clinical features, prognostic factors, and survival outcomes for patients with intracranial nongerminomatous germ cell…”
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Efficacy and safety of combined immunotherapy and stereotactic radiosurgery in NSCLCBM patients and a novel prognostic nomogram: A real-world study
Published in Frontiers in oncology (14-04-2023)“…To explore the effectiveness of combined immunotherapy (IT) and stereotactic radiosurgery (SRS) and address the gap between evidence-based clinical practice…”
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A Novel Six Autophagy-Related Genes Signature Associated With Outcomes and Immune Microenvironment in Lower-Grade Glioma
Published in Frontiers in genetics (13-10-2021)“…Since autophagy and the immune microenvironment are deeply involved in the tumor development and progression of Lower-grade gliomas (LGG), our study aimed to…”
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Development and validation of a nomogram to predict leptomeningeal metastases in lung adenocarcinoma: Cervical lymph node metastasis is an important association factor
Published in Cancer medicine (Malden, MA) (01-05-2024)“…Background The goal of this study was to create a nomogram using routine parameters to predict leptomeningeal metastases (LMs) in advanced lung adenocarcinoma…”
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11
Gene Signatures for Latent Radiation-Induced Lung Injury Post X-ray Exposure in Mouse
Published in Dose-response (01-04-2023)“…Objective To investigate the X-ray-specific sensitive genes and potential signaling pathways involved in the latent period of radiation-induced lung injury…”
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Individualized Nomogram for Predicting Survival in Patients with Brain Metastases After Stereotactic Radiosurgery Utilizing Driver Gene Mutations and Volumetric Surrogates
Published in Frontiers in oncology (13-05-2021)“…It is well-known that genomic mutational analysis plays a significant role in patients with NSCLC for personalized treatment. Given the increasing use of…”
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13
Lorlatinib for ALK‐fused, infant‐type hemispheric glioma with lung metastasis: a case report
Published in Annals of clinical and translational neurology (01-05-2023)“…Infant‐type hemispheric glioma, a new subtype of pediatric high‐grade glioma, arises in the cerebral hemispheres. Despite better survival outcomes, the…”
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CNSC-35. TEMOZOLOMIDE POTENTIALLY POSTPONES THE DEVELOPMENT OF SUBSEQUENT METASTASES IN PEDIATRIC DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) PATIENTS
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2024)“…Abstract OBJECTIVE Surgical intervention is thought to increase the likelihood of subsequent dissemination in diffuse intrinsic pontine glioma (DIPG) patients…”
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CNSC-34. SURGICAL INTERVENTION ASSOCIATION WITH THE DEVELOPMENT OF SUBSEQUENT DISSEMINATION IN CHILDHOOD DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPG)
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2024)“…Abstract BACKGROUND Diffuse intrinsic pontine glioma (DIPG) is one of the most aggressive pediatric central nervous system tumors, and currently, there are no…”
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MDB-13. CURRENT STATUS OF DIAGNOSIS AND TREATMENT FOR HIGH-RISK STAGE M2/M3 NON-WNT SUBTYPES MEDULLOBLASTOMA IN SOUTH CHINA
Published in Neuro-oncology (Charlottesville, Va.) (12-06-2023)“…Abstract OBJECTIVE To analyze the current diagnosis and treatment status of high-risk stage M2/M3 non-WNT types medulloblastoma in China, and explore the…”
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OTHR-25 Germline Mutations in Pediatric Brain Tumor
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract BACKGROUND: The exploration of germline mutations in pediatric brain tumor is helpful to improve the understanding of tumor genesis, guide the…”
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PATH-07. Diagnostic and therapeutic value of cerebrospinal fluid biopsy in pediatric brain tumors
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract BACKGROUND: The application of cerebrospinal fluid (CSF) biopsy in brain tumors is valuable. This paper further explores the diagnostic and…”
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MEDB-58. Risk factors and risk prediction models for medulloblastoma recurrence
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract BACKGROUND: There is a clear need for systematic appraisal of models/factors predicting medulloblastoma recurrence because clinical decisions about…”
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LGG-36. Analysis of BRAF-related mutations in pediatric low-grade glioma
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract BACKGROUND: Most pediatric low-grade gliomas (pLGGs) are driven by a single genetic event resulting in up-regulation of the RAS/MAPK pathway…”
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