Search Results - "Lai, Fernand"
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The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification
Published in Kidney international (01-09-2009)“…IgA nephropathy is the most common glomerular disease worldwide, yet there is no international consensus for its pathological or clinical classification. Here…”
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The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility
Published in Kidney international (01-09-2009)“…Pathological classifications in current use for the assessment of glomerular disease have been typically opinion-based and built on the expert assumptions of…”
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3
Urinary Long Non-Coding RNA Levels as Biomarkers of Lupus Nephritis
Published in International journal of molecular sciences (01-07-2023)“…Emerging evidence suggests that long non-coding RNA (lncRNA) plays important roles in the regulation of gene expression. We determine the role of using urinary…”
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4
Intrarenal expression of microRNAs in patients with IgA nephropathy
Published in Laboratory investigation (01-01-2010)“…MicroRNAs (miRNAs) are noncoding, single-stranded RNA molecules that have important roles in a number of physiological and pathological processes. Previous…”
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Urinary miR-21, miR-29, and miR-93: novel biomarkers of fibrosis
Published in American journal of nephrology (01-01-2012)“…MicroRNAs (miRNAs) play important roles in the progression of renal fibrosis. We studied the urinary levels of miR-21, miR-29 family and miR-93, which are…”
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6
Long-term Outcome of Biopsy-Proven Minimal Change Nephropathy in Chinese Adults
Published in American journal of kidney diseases (01-05-2015)“…Background Minimal change nephropathy is a common cause of primary nephrotic syndrome in adults. However, there are few studies of its clinical course,…”
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Urinary mi-106a for the diagnosis of IgA nephropathy: Liquid biopsy for kidney disease
Published in Clinica chimica acta (01-05-2022)“…•Previous studies showed that urinary levels of some miRNA targets are significantly altered in IgA nephropathy.•The persent study used healthy subjects and…”
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8
Glomerular and tubulointerstitial miR-638, miR-198 and miR-146a expression in lupus nephritis
Published in Nephrology (Carlton, Vic.) (01-05-2012)“…ABSTRACT Aim: MicroRNAs (miRNAs) play important roles in the pathogenesis of autoimmune diseases. We studied the intra‐renal expression of miRNA targets that…”
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9
Up-regulated pancreatic tissue microRNA-375 associates with human type 2 diabetes through beta-cell deficit and islet amyloid deposition
Published in Pancreas (01-08-2010)“…The aim of this study was to examine correlations of the islet-specific microRNA-375 expression to islet amyloid formation and pancreatic islet damage in human…”
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10
Urinary sediment miRNA levels in adult nephrotic syndrome
Published in Clinica chimica acta (15-03-2013)“…MicroRNAs are a group of non-coding RNA molecules that play important roles in the pathogenesis of various kidney diseases. We investigate the urinary sediment…”
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11
Acute renal impairment in coronavirus-associated severe acute respiratory syndrome
Published in Kidney international (01-02-2005)“…Acute renal impairment in coronavirus-associated severe acute respiratory syndrome. Severe acute respiratory syndrome (SARS) is a newly emerged infection from…”
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12
Expression and Functional Study of Estrogen Receptor-Related Receptors in Human Prostatic Cells and Tissues
Published in The journal of clinical endocrinology and metabolism (01-03-2005)“…Estrogen receptor-related receptors (ERRs; α, β, γ) are orphan nuclear receptors and constitutively active without binding to estrogen. Like estrogen receptors…”
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13
Causes of nephrotic syndrome and nephrotic‐range proteinuria are different in adult Chinese patients: A single centre study over 33 years
Published in Nephrology (Carlton, Vic.) (01-06-2018)“…Aim The reported causes of nephrotic syndrome (NS) varies between different countries. Less is known about the causes of nephrotic‐range proteinuria (NPU). We…”
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14
The gene expression of type 17 T-helper cell-related cytokines in the urinary sediment of patients with systemic lupus erythematosus
Published in Rheumatology (Oxford, England) (01-12-2009)“…Objective. We studied the role of type 17 Th cells (TH17) in the pathogenesis of SLE. Methods. We quantified the mRNA expression of IL-17, -23, -27 and…”
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Elevated levels of miR-146a and miR-155 in kidney biopsy and urine from patients with IgA nephropathy
Published in Disease markers (01-01-2011)“…BACKGROUNDPrevious studies suggested miR-146a and miR-155 play important roles in innate and adaptive immune responses. We studied intra-renal and urinary…”
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Prostate Health Index and %p2PSA Predict Aggressive Prostate Cancer Pathology in Chinese Patients Undergoing Radical Prostatectomy
Published in Annals of surgical oncology (01-08-2016)“…Purpose To investigate the performance of prostate health index (PHI) and percentage prostate-specific antigen (PSA) isoform [−2]proPSA (%p2PSA) in predicting…”
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Activation of podocytes by mesangial-derived TNF-alpha: glomerulo-podocytic communication in IgA nephropathy
Published in American journal of physiology. Renal physiology (01-04-2008)“…We have previously documented that human mesangial cell (HMC)-derived TNF-alpha is an important mediator involved in the glomerulo-tubular communication in the…”
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Intrarenal Expression of miRNAs in Patients With Hypertensive Nephrosclerosis
Published in American journal of hypertension (01-01-2010)“…Background MicroRNAs (miRNAs) are non-coding, single-stranded RNA molecules that play important roles in a number of physiological and pathological processes…”
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19
Fat redistribution and adipocyte transformation in uninephrectomized rats
Published in Kidney international (01-08-2008)“…Dyslipidemia complicates renal function leading to disturbances of major homeostatic organs in the body. Here we examined the effect of chronic renal…”
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Ultrasound-guided synovial Tru-cut biopsy: indications, technique, and outcome in 111 cases
Published in European radiology (01-05-2017)“…Objective To investigate the diagnostic performance of ultrasound-guided synovial biopsy. Methods Clinical notes, pathology and microbiology reports,…”
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