Search Results - "Lai, Edward K"

Specificity of a phenobarbital-induced cytochrome P-450 for metabolism of carbon tetrachloride to the trichloromethyl radical by Noguchi, T, Fong, K L, Lai, E K, Alexander, S S, King, M M, Olson, L, Poyer, J L, McCay, P B

“…Evidence is presented which demonstrates that the first polypeptide to disappear in liver microsomes of phenobarbital-induced rats treated with CC14 was the…”
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Marked Reduction of Free Radical Generation and Contractile Dysfunction by Antioxidant Therapy Begun at the Time of Reperfusion Evidence That Myocardial "Stunning" Is a Manifestation of Reperfusion Injury by Bolli, Roberto, Jeroudi, Mohamed O, Patel, Bharat S, Aruoma, Okezie I, Halliwell, Barry, Lai, Edward K, McCay, Paul B

“…Recent evidence suggests that postischemic myocardial dysfunction (“stunning”) may be mediated by oxygen free radicals, but the exact time window during which…”
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Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog by Bolli, R, Jeroudi, M.O, Patel, B.S, DuBose, C.M, Lai, E.K, Roberts, R, McCay, P.B

“…Electron paramagnetic resonance (EPR) spectroscopy was used to investigate whether (i) the free radicals produced in the ``stunned'' myocardium (myocardium…”
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Evidence that alpha-tocopherol functions cyclically to quench free radicals in hepatic microsomes. Requirement for glutathione and a heat-labile factor by McCay, P B, Brueggemann, G, Lai, E K, Powell, S R

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In vivo spin trapping of free radicals generated in brain, spleen, and liver during gamma radiation of mice by Lai, E K, Crossley, C, Sridhar, R, Misra, H P, Janzen, E G, McCay, P B

“…Spin trapping techniques combined with electron spin resonance spectroscopy were used to capture and detect free radicals generated in vivo during exposure to…”
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Spin trapping of free radicals produced in vivo in heart and liver during endotoxemia by Brackett, D J, Lai, E K, Lerner, M R, Wilson, M F, McCay, P B

“…Studies using free radical scavengers and measurements of lipid peroxidation have suggested that free radicals are generated during endotoxemia. Conclusions…”
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Selective early loss of polypeptides in liver microsomes of CCl4-treated rats. Relationship to cytochrome P-450 content by Noguchi, T, Fong, K L, Lai, E K, Olson, L, McCay, P B

“…Treatment of rats with carbon tetrachloride (CCl4) resulted in early reproducible losses of either one or two specific polypeptides (depending on the inducing…”
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In vivo spin-trapping of trichloromethyl radicals formed from CCl4 by Lai, E K, McCay, P B, Noguchi, T, Fong, K L

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Ethanol feeding stimulates trichloromethyl radical formation from carbon tetrachloride in liver by Reinke, L A, Lai, E K, McCay, P B

“…1. Female, Sprague-Dawley rats were fed liquid ethanol or control diets, both of which contained fat either at 35% (high fat, HF) or 12% (low fat, LF) of total…”
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An update on antioxidant theory: spin trapping of trichloromethyl radicals in vivo by McCay, P B, King, M M, Poyer, J L, Lai, E K

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Gulonolactone Oxidase by Eliceiri, G L, Lai, E K, McCay, P B

“…A gulonolactone oxidase ( l -gulono-γ-lactone:O 2 oxidoreductase, EC 1.1.3.b) preparation was obtained from rat liver microsomes in which the enzyme was…”
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Studies on the properties of the singlet oxygen-like factor produced during lipid peroxidation by Lai, E K, Fong, K L, McCay, P B

“…The singlet oxygen reaction product of various trapping agents is observed during enzymic and nonenzymic peroxidation of microsomes as well as during the…”
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