Search Results - "Lahti, R."
-
1
Enzymes regulated via cystathionine β-synthase domains
Published in Biochemistry (Moscow) (01-10-2017)“…Cystathionine β-synthase (CBS) domains discovered 20 years ago can bind different adenosine derivatives (AMP, ADP, ATP, S-adenosylmethionine, NAD, diadenosine…”
Get full text
Journal Article -
2
The validity of death certificates: routine validation of death certification and its effects on mortality statistics
Published in Forensic science international (2001)“…The 3478 death certificates (7.1% of all annual death certificates) of this study comprise those national death certificates in 1995 submitted for validation…”
Get full text
Journal Article -
3
How precise is egg discrimination in weaverbirds?
Published in Animal behaviour (01-06-2002)“…The village weaverbird, Ploceus cucullatus, lays eggs of an extremely broad range of appearance between individuals. This variation is thought to have evolved…”
Get full text
Journal Article -
4
Cause and manner of death and phase of the blood alcohol curve
Published in Forensic science international (01-11-2014)“…Highlights • Phase of the blood–alcohol curve at time of death was estimated from the concentrations of ethanol in blood and urine at autopsy. • People dying…”
Get full text
Journal Article -
5
Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridium perfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate
Published in Journal of molecular biology (07-05-2010)“…Nucleotide-binding cystathionine b-synthase (CBS) domains serve as regulatory units in numerous proteins distributed in all kingdoms of life. However, the…”
Get full text
Journal Article -
6
Cause-of-death query in validation of death certification by expert panel; effects on mortality statistics in Finland, 1995
Published in Forensic science international (28-01-2003)“…The correctness of selection, coding and registration of underlying cause-of-death is important for the quality of mortality statistics. One measure to improve…”
Get full text
Journal Article -
7
Stimulating and inhibitory effects of the dopamine "stabilizer" (-)-OSU6162 on dopamine D2 receptor function in vitro
Published in Journal of Neural Transmission (01-09-2007)“…The effect of (-)-OSU6162 on the incorporation of GTPgammaS(35) in the membranes of hD(2l)-transfected CHO cells was investigated. In the absence of dopamine…”
Get full text
Journal Article -
8
Blood-positive illicit-drug findings: Implications for cause-of-death certification, classification and coding
Published in Forensic science international (30-05-2009)“…Abstract National cause-of-death data are important for national health administration, international comparisons and epidemiological research. The process of…”
Get full text
Journal Article -
9
Toward a Quantum-Mechanical Description of Metal-Assisted Phosphoryl Transfer in Pyrophosphatase
Published in Proceedings of the National Academy of Sciences - PNAS (13-03-2001)“…The wealth of kinetic and structural information makes inorganic pyrophosphatases (PPases) a good model system to study the details of enzymatic phosphoryl…”
Get full text
Journal Article -
10
Fatal drug poisonings: medico-legal reports and mortality statistics
Published in Forensic science international (09-09-2003)“…The entire fatal drug poisoning panorama in Finland is considered in terms of three categories: accidental, self-inflicted and undetermined (whether accidental…”
Get full text
Journal Article -
11
Fatal alcohol poisoning: medico-legal practices and mortality statistics
Published in Forensic science international (23-05-2002)“…Compilation of mortality statistics from death certificate data is based on international and national conventions which in certain situations result in the…”
Get full text
Journal Article -
12
Fast kinetics of nucleotide binding to Clostridium perfringens family II pyrophosphatase containing CBS and DRTGG domains
Published in Biochemistry (Moscow) (01-02-2012)“…We earlier described CBS-pyrophosphatase of Moorella thermoacetica ( mt CBS-PPase) as a novel phosphohydrolase that acquired a pair of nucleotide-binding CBS…”
Get full text
Journal Article -
13
Direct determination of dopamine D4 receptors in normal and schizophrenic postmortem brain tissue : a [3H]NGD-94-1 study
Published in Molecular psychiatry (01-11-1998)“…Using an indirect subtraction binding technique and human postmortem tissue, several laboratories reported finding increases in dopamine D4 receptors in…”
Get full text
Journal Article -
14
Crystal Structures of the CBS and DRTGG Domains of the Regulatory Region of Clostridiumperfringens Pyrophosphatase Complexed with the Inhibitor, AMP, and Activator, Diadenosine Tetraphosphate
Published in Journal of molecular biology (07-05-2010)“…Nucleotide-binding cystathionine β-synthase (CBS) domains serve as regulatory units in numerous proteins distributed in all kingdoms of life. However, the…”
Get full text
Journal Article -
15
Antipsychotic Properties of the Partial Dopamine Agonist (−)-3-(3-Hydroxyphenyl)-N-n-Propylpiperidine (Preclamol) in Schizophrenia
Published in Biological psychiatry (1969) (1998)“…Background: In an ongoing effort to characterize the clinical pharmacologic profile of the partial dopamine agonist…”
Get full text
Journal Article -
16
Inhibition of family II pyrophosphatases by analogs of pyrophosphate and phosphate
Published in Biochemistry (Moscow) (01-08-2005)“…Imidodiphosphate (the pyrophosphate analog containing a nitrogen atom in the bridge position instead of oxygen) is a potent inhibitor of family II…”
Get full text
Journal Article -
17
Intrinsic activity determinations at the dopamine D2 guanine nucleotide-binding protein-coupled receptor: utilization of receptor state binding affinities
Published in Molecular pharmacology (01-09-1992)“…Guanine nucleotide-binding protein-coupled receptors have been shown to exist in both a high affinity agonist (HiAg) and a low affinity agonist (LowAg) state…”
Get more information
Journal Article -
18
U-78517F: a potent inhibitor of lipid peroxidation with activity in experimental brain injury and ischemia
Published in The Journal of pharmacology and experimental therapeutics (01-08-1991)“…U-78517F (2-[4-[2,6-di-(1-pyrrolidinyl)-4-pyridinyl)-1-piperazinyl] methyl]-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol, dihydrochloride), which…”
Get more information
Journal Article -
19
U-50,488: a selective and structurally novel non-Mu (kappa) opioid agonist
Published in The Journal of pharmacology and experimental therapeutics (01-01-1983)“…U-50,488 (trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzeneacetamide) displays analgesic actions in a variety (thermal, pressure and…”
Get more information
Journal Article -
20
Exploitation of autopsy in determining natural cause of death: Trends in Finland with special reference to the diagnostics of ischemic heart diseases and cerebrovascular diseases in middle-aged males, 1974–1993
Published in Forensic science international (30-01-1998)“…Finnish mortality statistics show a marked decrease in coronary disease mortality especially among middle-aged males during the last 20 to 25 years. At the…”
Get full text
Journal Article