Search Results - "Lahoutte, T."
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Next-generation muscle-directed gene therapy by in silico vector design
Published in Nature communications (30-01-2019)“…There is an urgent need to develop the next-generation vectors for gene therapy of muscle disorders, given the relatively modest advances in clinical trials…”
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CAM-H2 effectively targets and treats HER2 positive brain lesions: A comparative preclinical study with trastuzumab
Published in Annals of oncology (01-05-2019)Get full text
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3
Imaging and radioimmunotherapy of multiple myeloma with anti-idiotypic Nanobodies
Published in Leukemia (01-02-2014)Get full text
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Phase II trial of HER2-PET/CT using 68Ga-anti-HER2 VHH1 for characterization of HER2 presence in brain metastases of breast cancer patients
Published in Annals of oncology (01-05-2019)Get full text
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5
Human blood outgrowth endothelial cells improve islet survival and function when co-transplanted in a mouse model of diabetes
Published in Diabetologia (01-02-2013)“…Aims/hypothesis As current islet-transplantation protocols suffer from significant graft loss and dysfunction, strategies to sustain the long-term benefits of…”
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Biological carrier molecules of radiopharmaceuticals for molecular cancer imaging and targeted cancer therapy
Published in Current pharmaceutical design (01-01-2014)“…Many tumors express one or more proteins that are either absent or hardly present in normal tissues, and which can be targeted by radiopharmaceuticals for…”
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7
Using microdialysis to analyse the passage of monovalent nanobodies through the blood–brain barrier
Published in British journal of pharmacology (01-04-2012)“…BACKGROUND AND PURPOSE Nanobodies are promising antigen‐binding moieties for molecular imaging and therapeutic purposes because of their favourable…”
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Influence of Heart Rate Reduction on Doppler Myocardial Imaging Parameters in a Small Animal Model
Published in Ultrasound in medicine & biology (01-01-2009)“…Abstract In small animals studies, sick animals often have a significant reduction in heart rate while under anesthesia. The influence of heart rate reduction…”
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The role of diffusion-weighted MR imaging and ADC values in the diagnosis of gastric tumors
Published in Journal of the Belgian Society of Radiology (01-09-2012)“…In order to exclude acute pulmonary embolism, a lung perfusion scintigraphy was performed in a 53-year-old male, with a history of Fallot’s tetralogy. He had…”
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10
Quality control of micro-computed tomography systems
Published in Radiation protection dosimetry (01-04-2010)“…The rapid proliferation of micro-computed tomography (micro-CT) scanners in preclinical small animal studies has created a need for a method on scanner…”
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Complete right-to-left shunt on lung perfusion SPECT results in the detection of a persistent left vena cava superior draining to the left atrium
Published in Journal of the Belgian Society of Radiology (01-09-2012)“…In order to exclude acute pulmonary embolism, a lung perfusion scintigraphy was performed in a 53-year-old male, with a history of Fallot’s tetralogy. He had…”
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12
Synthesis, radiosynthesis, and in vitro characterization of [ 125I]-2- iodo-L-phenylalanine in a R1M rhabdomyosarcoma cell model as a new potential tumor tracer for SPECT
Published in Nuclear medicine and biology (01-08-2004)“…[ 125I]-2-iodo-L-phenylalanine, a new radioiodinated phenylalanine analog was evaluated as a potential specific tumor tracer for SPECT. The tracer is obtained…”
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184PCAM-H2 effectively targets and treats HER2 positive brain lesions: A comparative preclinical study with trastuzumab
Published in Annals of oncology (01-05-2019)Get full text
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14
Labelled sigma receptor ligands: can their role in neurology and oncology be extended?
Published in European Journal of Nuclear Medicine (01-02-2001)Get full text
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15
In vitro characterization of the influx of 3-[ 125I]iodo-L-α-methyltyrosine and 2-[ 125I]iodo-L-tyrosine into U266 human myeloma cells: Evidence for System T transport
Published in Nuclear medicine and biology (01-02-2001)“…The aim of this study was to investigate the cellular uptake mechanisms responsible for the accumulation of 3-[ 125I]iodo-L-α-methyltyrosine ( 125I-3-IMT) and…”
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Labeling of Anti-HER2 Nanobodies with Astatine-211: Optimization and the Effect of Different Coupling Reagents on Their in Vivo Behavior
Published in Molecular pharmaceutics (05-08-2019)“…The use of nanobodies (Nbs) as vehicles in targeted alpha therapy (TAT) has gained great interest because of their excellent properties. They combine high in…”
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85TiPPhase II trial of HER2-PET/CT using 68Ga-anti-HER2 VHH1 for characterization of HER2 presence in brain metastases of breast cancer patients
Published in Annals of oncology (01-05-2019)Get full text
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Diagnosis of recurrent head and neck squamous cell carcinoma with 3-[123I]iodo-L-alpha-methyltyrosine SPET
Published in European Journal of Nuclear Medicine (01-03-2001)“…The distribution of 3-[123I]iodo-L-alpha-methyltyrosine (123I-3-IMT) in the tumour region of 21 patients with clinically suspected recurrent squamous cell head…”
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Evaluation of the response to therapy of head and neck squamous cell carcinoma by using 3-[123I]iodo-L-α-methyl tyrosine and single photon emission tomography
Published in Nuclear medicine communications (01-06-2003)“…Early detection of residual tumour tissue offers the possibility for rapid administration of adjuvant treatment. Single photon emission tomography (SPET) with…”
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Complete right-to-left shunt on lung perfusion SPECT results in the detection of a persistent left vena cava superior draining to the left atrium
Published in JBR-BTR : organe de la Societe royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR) (01-09-2012)Get more information
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