Search Results - "Lahkar, Mangala"

Amelioration of Repeated Restraint Stress-Induced Behavioral Deficits and Hippocampal Anomalies with Taurine Treatment in Mice by Jangra, Ashok, Rajput, Prabha, Dwivedi, Durgesh Kumar, Lahkar, Mangala

“…Taurine, an essential neutraceutical, has been reported to exhibit antioxidant and anti-inflammatory properties. Substantial evidence indicates that prolonged…”
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Therapeutic targets of triple‐negative breast cancer: a review by Jamdade, Vinayak S, Sethi, Nikunj, Mundhe, Nitin A, Kumar, Parveen, Lahkar, Mangala, Sinha, Neeraj

“…Breast cancer (BC) is the second most common cause of cancer deaths. Triple‐negative breast cancer (TNBC) does not show immunohistochemical expression of…”
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7,8-Dihydroxyflavone alleviated the high-fat diet and alcohol-induced memory impairment: behavioral, biochemical and molecular evidence by Pandey, Surya Narayan, Kwatra, Mohit, Dwivedi, Durgesh Kumar, Choubey, Priyansha, Lahkar, Mangala, Jangra, Ashok

“…Rationale Alcoholism and obesity impart a deleterious impact on human health and affects the quality of life. Chronic consumption of alcohol and western diet…”
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An Overview of the Heterogeneity of Major Depressive Disorder: Current Knowledge and Future Prospective by Athira, Kaipuzha Venu, Bandopadhyay, Sikta, Samudrala, Pavan Kumar, Naidu, V G M, Lahkar, Mangala, Chakravarty, Sumana

“…Major depressive disorder (MDD) is estimated to impose maximum debilitating effects on the society by 2030, with its critical effects on health, functioning,…”
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The ubiquitin proteasomal system: a potential target for the management of Alzheimer's disease by Gadhave, Kundlik, Bolshette, Nityanand, Ahire, Ashutosh, Pardeshi, Rohit, Thakur, Krishan, Trandafir, Cristiana, Istrate, Alexandru, Ahmed, Sahabuddin, Lahkar, Mangala, Muresanu, Dafin F., Balea, Maria

“…The cellular quality control system degrades abnormal or misfolded proteins and consists of three different mechanisms: the ubiquitin proteasomal system (UPS),…”
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Molecular and biochemical evidence on the protective effects of quercetin in isoproterenol‐induced acute myocardial injury in rats by Kumar, Mukesh, Kasala, Eshvendar Reddy, Bodduluru, Lakshmi Narendra, Kumar, Vikas, Lahkar, Mangala

“…Cardioprotection represents one of the most important and realistic aspects of preventive therapy today. Quercetin, a naturally occurring dietary flavone, has…”
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Hesperidin and Silibinin Ameliorate Aluminum-Induced Neurotoxicity: Modulation of Antioxidants and Inflammatory Cytokines Level in Mice Hippocampus by Jangra, Ashok, Kasbe, Prajapati, Pandey, Surya Narayan, Dwivedi, Shubham, Gurjar, Satendra S, Kwatra, Mohit, Mishra, Murli, Venu, Athira K, Sulakhiya, Kunjbihari, Gogoi, Ranadeep, Sarma, Nitul, Bezbaruah, Babul K, Lahkar, Mangala

“…Mounting evidence suggests that long-term aluminum exposure results in severe toxic effects, including neurobehavioral and neurochemical anomalies. The present…”
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Docosahexaenoic Acid Increases the Potency of Soluble Epoxide Hydrolase Inhibitor in Alleviating Streptozotocin-Induced Alzheimer's Disease-Like Complications of Diabetes by Pardeshi, Rohit, Bolshette, Nityanand, Gadhave, Kundlik, Arfeen, Mohammad, Ahmed, Sahabuddin, Jamwal, Rohitash, Hammock, Bruce D, Lahkar, Mangala, Goswami, Sumanta Kumar

“…Diabetes is a risk factor for Alzheimer's disease and it is associated with significant memory loss. In the present study, we hypothesized that the soluble…”
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A study on adverse drug reactions in a tertiary care hospital of Northeast India by Lihite, Ratan J., Lahkar, Mangala, Das, Sukirti, Hazarika, Debeeka, Kotni, Murali, Maqbool, Mudasir, Phukan, Swapna

“…Purpose of this study was to monitor adverse drug reactions reported from various departments of a tertiary care hospital in Northeast India. Reported adverse…”
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An Early Sign of Wilson's Disease: Dysarthria by Lihite, Ratan J, Choudhury, Urmi, Surender, G, Pal, Biplab, Lahkar, Mangala

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Crocin attenuates cyclophosphamide induced testicular toxicity by preserving glutathione redox system by Potnuri, Ajay Godwin, Allakonda, Lingesh, Lahkar, Mangala

“…[Display omitted] Chemotherapy induced testicular toxicity is an emerging reason for azoospermia and impotency in males. Cyclophosphamide (CP) is a widely used…”
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Mangiferin ameliorates aluminium chloride-induced cognitive dysfunction via alleviation of hippocampal oxido-nitrosative stress, proinflammatory cytokines and acetylcholinesterase level by Kasbe, Prajapati, Jangra, Ashok, Lahkar, Mangala

“…Mangiferin is a phytochemical primarily present in the stem, leaves and bark of Mangifera indica. It offers neuroprotection mainly through inhibition of…”
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Lipopolysaccharide-Induced Behavioral Alterations Are Alleviated by Sodium Phenylbutyrate via Attenuation of Oxidative Stress and Neuroinflammatory Cascade by Jangra, Ashok, Sriram, Chandra Shaker, Lahkar, Mangala

“…Oxido-nitrosative stress, neuroinflammation, and reduced level of neurotrophins are implicated in the pathophysiology of anxiety and depressive illness. A few…”
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Hepatoprotective potential of 7,8-Dihydroxyflavone against alcohol and high-fat diet induced liver toxicity via attenuation of oxido-nitrosative stress and NF-κB activation by Kumar, Dinesh, Dwivedi, Durgesh Kumar, Lahkar, Mangala, Jangra, Ashok

“…Fatty liver diseases are the most common and major health concern arises from the modern lifestyle and alcohol (ethanol) abuse. The prevalence of non-alcoholic…”
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Baicalein protects isoproterenol induced myocardial ischemic injury in male Wistar rats by mitigating oxidative stress and inflammation by Kumar, Mukesh, Kasala, Eshvendar Reddy, Bodduluru, Lakshmi Narendra, Dahiya, Vicky, Lahkar, Mangala

“…Objective The aim of the present study was to investigate the cardioprotective effects of baicalein, main bioactive constituent from roots of Scutellaria…”
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Diosmin Modulates the NF-kB Signal Transduction Pathways and Downregulation of Various Oxidative Stress Markers in Alloxan-Induced Diabetic Nephropathy by Ahmed, Sahabuddin, Mundhe, Nitin, Borgohain, Manash, Chowdhury, Liakat, Kwatra, Mohit, Bolshette, Nityanand, Ahmed, Anwaruddin, Lahkar, Mangala

“…Hyperglycaemia-mediated oxidative stress plays an imperative role in the progression of diabetic nephropathy. NF-kB is an important transcription factor in…”
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Edaravone alleviates cisplatin-induced neurobehavioral deficits via modulation of oxidative stress and inflammatory mediators in the rat hippocampus by Jangra, Ashok, Kwatra, Mohit, Singh, Tavleen, Pant, Rajat, Kushwah, Pawan, Ahmed, Sahabuddin, Dwivedi, Durgesh, Saroha, Babita, Lahkar, Mangala

“…Cisplatin is a chemotherapeutic agent used in the treatment of malignant tumors. A major clinical limitation of cisplatin is its potential toxic effects,…”
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Ameliorative effect of fisetin against lipopolysaccharide and restraint stress-induced behavioral deficits via modulation of NF-[kappa]B and IDO-1 by Choubey, Priyansha, Kwatra, Mohit, Pandey, Surya Narayan, Kumar, Dinesh, Dwivedi, Durgesh Kumar, Rajput, Prabha, Mishra, Abhishek

“…Background Fisetin, a plant active polyphenol, is well known for its antioxidant and free radical scavenging activities. The present study was designed to…”
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Lipopolysaccharide induced anxiety- and depressive-like behaviour in mice are prevented by chronic pre-treatment of esculetin by Sulakhiya, Kunjbihari, Keshavlal, Gohil Pratik, Bezbaruah, Babul B., Dwivedi, Shubham, Gurjar, Satendra Singh, Munde, Nitin, Jangra, Ashok, Lahkar, Mangala, Gogoi, Ranadeep

“…[Display omitted] •ESC pre-treatment attenuated LPS-induced anxiety- & depressive-like behaviour in mice.•LPS-induced elevated brain IL-1β, IL-6, and TNF-α…”
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Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice by Jangra, Ashok, Lukhi, Manish M., Sulakhiya, Kunjbihari, Baruah, Chandana C., Lahkar, Mangala

“…Numerous studies have demonstrated that inflammation, oxidative stress and altered level of neurotrophins are involved in the pathogenesis of depressive…”
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