Search Results - "Lahiri, Abhishake"
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Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities
Published in Nature communications (14-06-2021)“…Yeast is an integral part of mammalian microbiome, and like commensal bacteria, has the potential of being harnessed to influence immunity in clinical…”
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Butyrate limits inflammatory macrophage niche in NASH
Published in Cell death & disease (18-05-2023)“…Immune cell infiltrations with lobular inflammation in the background of steatosis and deregulated gut-liver axis are the cardinal features of non-alcoholic…”
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3
Proteasome dysfunction under compromised redox metabolism dictates liver injury in NASH through ASK1/PPARγ binodal complementary modules
Published in Redox biology (01-09-2021)“…Incidence of hepatotoxicity following acute drug-induced proteasomal inhibition and development of chronic proteasome dysfunction in obesity and insulin…”
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Association of gut microbial dysbiosis with disease severity, response to therapy and disease outcomes in Indian patients with COVID-19
Published in Gut pathogens (10-05-2023)“…Severe coronavirus disease 2019 (COVID-19) is associated with systemic hyper-inflammation. An adaptive interaction between gut microbiota and host immune…”
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Interplay of Various Evolutionary Modes in Genome Diversification and Adaptive Evolution of the Family Sulfolobaceae
Published in Frontiers in microbiology (25-06-2021)“…Sulfolobaceae family, comprising diverse thermoacidophilic and aerobic sulfur-metabolizing Archaea from various geographical locations, offers an ideal…”
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6
Human FKBP5 Negatively Regulates Transcription through Inhibition of P-TEFb Complex Formation
Published in Molecular and cellular biology (20-01-2022)“…Although a large number of recent studies indicate strong association of FKBP5 (aka FKBP51) functions with various stress-related psychiatric disorders, the…”
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Integrating Multi-Omics Data to Construct Reliable Interconnected Models of Signaling, Gene Regulatory, and Metabolic Pathways
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Alteration of the status of the metabolic enzymes could be a probable way to regulate metabolic reprogramming, which is a critical cellular adaptation…”
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8
Microbiome Metabolome Integration Platform (MMIP): a web-based platform for microbiome and metabolome data integration and feature identification
Published in Briefings in bioinformatics (22-09-2023)“…Abstract A microbial community maintains its ecological dynamics via metabolite crosstalk. Hence, knowledge of the metabolome, alongside its populace, would…”
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Exploring the resistome and virulome in major sequence types of Acinetobacter baumannii genomes: Correlations with genome divergence and sequence types
Published in Infection, genetics and evolution (01-04-2024)“…The increasing global prevalence of antimicrobial resistance in Acinetobacter baumannii has led to concerns regarding the effectiveness of infection treatment…”
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Nature and Dimensions of Systemic Hyperinflammation and its Attenuation by Convalescent Plasma in Severe COVID-19
Published in The Journal of infectious diseases (16-08-2021)“…Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19), has led to significant morbidity…”
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MACI: A machine learning-based approach to identify drug classes of antibiotic resistance genes from metagenomic data
Published in Computers in biology and medicine (01-12-2023)“…Novel methodologies are now essential for identification of antibiotic resistant pathogens in order to resist them. Here, we are presenting a model, MACI…”
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A phase 2 single center open label randomised control trial for convalescent plasma therapy in patients with severe COVID-19
Published in Nature communications (19-01-2022)“…A single center open label phase 2 randomised control trial (Clinical Trial Registry of India No. CTRI/2020/05/025209) was done to assess clinical and…”
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13
Nature and dimensions of the systemic hyper-inflammation and its attenuation by convalescent plasma in severe COVID-19
Published in The Journal of infectious diseases (12-01-2021)“…Novel coronavirus SARS-CoV2, causing coronavirus disease 2019 or COVID-19, led to significant morbidity and mortality. While most suffer from mild symptoms,…”
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14
Nature and dimensions of the systemic hyper-inflammation and its attenuation by convalescent plasma in severe COVID-19
Published in The Journal of infectious diseases (12-01-2021)“…Novel coronavirus SARS-CoV2, causing coronavirus disease 2019 or COVID-19, led to significant morbidity and mortality. While most suffer from mild symptoms,…”
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