Search Results - "Lahav, Shlomtzion"
-
1
ConSurf‐DB: An accessible repository for the evolutionary conservation patterns of the majority of PDB proteins
Published in Protein science (01-01-2020)“…Patterns observed by examining the evolutionary relationships among proteins of common origin can reveal the structural and functional importance of specific…”
Get full text
Journal Article -
2
DNA methylation patterns expose variations in enhancer-chromatin modifications during embryonic stem cell differentiation
Published in PLoS genetics (12-04-2021)“…In mammals, cellular identity is defined through strict regulation of chromatin modifications and DNA methylation that control gene expression. Methylation of…”
Get full text
Journal Article -
3
Repetitive DNA symmetry elements negatively regulate gene expression in embryonic stem cells
Published in Biophysical journal (16-08-2022)“…Transcription factor (TF) binding to genomic DNA elements constitutes one of the key mechanisms that regulates gene expression program in cells. Both consensus…”
Get full text
Journal Article -
4
CRISPys: Optimal sgRNA Design for Editing Multiple Members of a Gene Family Using the CRISPR System
Published in Journal of molecular biology (20-07-2018)“…The development of the CRISPR–Cas9 system in recent years has made eukaryotic genome editing, and specifically gene knockout for reverse genetics, a simple and…”
Get full text
Journal Article -
5
Esrrb is a cell-cycle-dependent associated factor balancing pluripotency and XEN differentiation
Published in Stem cell reports (14-06-2022)“…Cell cycle and differentiation decisions are linked; however, the underlying principles that drive these decisions are unclear. Here, we combined cell-cycle…”
Get full text
Journal Article