Search Results - "Laguna‐Goya, Rocío"

Immunogenicity of Anti-SARS-CoV-2 Vaccines in Common Variable Immunodeficiency by Arroyo-Sánchez, Daniel, Cabrera-Marante, Oscar, Laguna-Goya, Rocío, Almendro-Vázquez, Patricia, Carretero, Octavio, Gil-Etayo, Francisco Javier, Suàrez-Fernández, Patricia, Pérez-Romero, Pilar, Rodríguez de Frías, Edgard, Serrano, Antonio, Allende, Luis M., Pleguezuelo, Daniel, Paz-Artal, Estela

“…Common variable immunodeficiency (CVID) is characterized by hypogammaglobulinemia and/or a defective antibody response to T-dependent and T-independent…”
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Tocilizumab for the treatment of adult patients with severe COVID‐19 pneumonia: A single‐center cohort study by Fernández‐Ruiz, Mario, López‐Medrano, Francisco, Pérez‐Jacoiste Asín, María Asunción, Maestro de la Calle, Guillermo, Bueno, Héctor, Caro‐Teller, José Manuel, Catalán, Mercedes, Calle, Cristina, García‐García, Rocío, Gómez, Carlos, Laguna‐Goya, Rocío, Lizasoáin, Manuel, Martínez‐López, Joaquín, Origüen, Julia, Pablos, José Luis, Ripoll, Mar, San Juan, Rafael, Trujillo, Hernando, Lumbreras, Carlos, Aguado, José María

“…Coronavirus disease 2019 (COVID‐19) can lead to a massive cytokine release. The use of the anti‐interleukin‐6 receptor monoclonal antibody tocilizumab (TCZ)…”
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T cell–mediated response to SARS‐CoV‐2 in liver transplant recipients with prior COVID‐19 by Fernández‐Ruiz, Mario, Olea, Beatriz, Almendro‐Vázquez, Patricia, Giménez, Estela, Marcacuzco, Alberto, San Juan, Rafael, Justo, Iago, Calvo‐Pulido, Jorge, García‐Sesma, Álvaro, Manrique, Alejandro, Caso, Oscar, Cambra, Félix, Talayero, Paloma, López‐Medrano, Francisco, Remigia, María José, Ruiz‐Merlo, Tamara, Parra, Patricia, Paz‐Artal, Estela, Jiménez, Carlos, Loinaz, Carmelo, Navarro, David, Laguna‐Goya, Rocío, Aguado, José M.

“…Whether immunosuppression impairs severe acute respiratory syndrome coronavirus 2‐specific T cell–mediated immunity (SARS‐CoV‐2‐CMI) after liver…”
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Circulatory follicular helper T lymphocytes associate with lower incidence of CMV infection in kidney transplant recipients by Suàrez‐Fernández, Patricia, Utrero‐Rico, Alberto, Sandonis, Virginia, García‐Ríos, Estéfani, Arroyo‐Sánchez, Daniel, Fernández‐Ruiz, Mario, Andrés, Amado, Polanco, Natalia, González‐Cuadrado, Cecilia, Almendro‐Vázquez, Patricia, Pérez‐Romero, Pilar, Aguado, José María, Paz‐Artal, Estela, Laguna‐Goya, Rocío

“…Primary infection and/or reactivation of cytomegalovirus (CMV) in kidney transplant recipients (KTR) favor rejection and mortality. T follicular helper cells…”
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Perforin gene variant A91V in young patients with severe COVID-19 by Cabrera-Marante, Oscar, Rodríguez de Frías, Edgard, Pleguezuelo, Daniel E, Allende, Luis M, Serrano, Antonio, Laguna-Goya, Rocío, Mancebo, María Esther, Talayero, Paloma, Álvarez-Vallina, Luis, Morales, Pablo, Castro-Panete, Maria José, Paz-Artal, Estela

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Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination by Horndler, Lydia, Delgado, Pilar, Romero-Pinedo, Salvador, Quesada, Marina, Balabanov, Ivaylo, Laguna-Goya, Rocío, Almendro-Vázquez, Patricia, Llamas, Miguel A, Fresno, Manuel, Paz-Artal, Estela, van Santen, Hisse M, Álvarez-Fernández, Stela, Olmo, Asunción, Alarcón, Balbino

“…The rapid development of vaccines to prevent COVID-19 has raised the need to compare the capacity of different vaccines in terms of developing a protective…”
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Alterations in Circulating Monocytes Predict COVID-19 Severity and Include Chromatin Modifications Still Detectable Six Months after Recovery by Utrero-Rico, Alberto, González-Cuadrado, Cecilia, Chivite-Lacaba, Marta, Cabrera-Marante, Oscar, Laguna-Goya, Rocío, Almendro-Vazquez, Patricia, Díaz-Pedroche, Carmen, Ruiz-Ruigómez, María, Lalueza, Antonio, Folgueira, María Dolores, Vázquez, Enrique, Quintas, Ana, Berges-Buxeda, Marcos J., Martín-Rodriguez, Moisés, Dopazo, Ana, Serrano-Hernández, Antonio, Aguado, José María, Paz-Artal, Estela

“…An early analysis of circulating monocytes may be critical for predicting COVID-19 course and its sequelae. In 131 untreated, acute COVID-19 patients at…”
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A Short Corticosteroid Course Reduces Symptoms and Immunological Alterations Underlying Long-COVID by Utrero-Rico, Alberto, Ruiz-Ruigómez, María, Laguna-Goya, Rocío, Arrieta-Ortubay, Estíbaliz, Chivite-Lacaba, Marta, González-Cuadrado, Cecilia, Lalueza, Antonio, Almendro-Vazquez, Patricia, Serrano, Antonio, Aguado, José María, Lumbreras, Carlos, Paz-Artal, Estela

“…Despite the growing number of patients with persistent symptoms after acute SARS-CoV-2 infection, the pathophysiology underlying long-COVID is not yet well…”
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Discordance Between SARS-CoV-2–specific Cell-mediated and Antibody Responses Elicited by mRNA-1273 Vaccine in Kidney and Liver Transplant Recipients by Fernández-Ruiz, Mario, Almendro-Vázquez, Patricia, Carretero, Octavio, Ruiz-Merlo, Tamara, Laguna-Goya, Rocío, San Juan, Rafael, López-Medrano, Francisco, García-Ríos, Estéfani, Más, Vicente, Moreno-Batenero, Miguel, Loinaz, Carmelo, Andrés, Amado, Pérez-Romero, Pilar, Paz-Artal, Estela, Aguado, José María

“…Severe acute respiratory syndrome coronavirus 2-specific cell-mediated immunity (SARS-CoV-2-CMI) elicited by mRNA-based vaccines in solid organ transplant…”
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Complement C3F allotype synthesized by liver recipient modifies transplantation outcome independently from donor hepatic C3 by Valero‐Hervás, Diana María, Sánchez‐Zapardiel, Elena, Castro, María José, Gallego‐Bustos, Fernando, Cambra, Félix, Justo, Iago, Laguna‐Goya, Rocío, Jiménez‐Romero, Carlos, Moreno, Enrique, López‐Medrano, Francisco, San Juan, Rafael, Fernández‐Ruiz, Mario, Aguado, José María, Paz‐Artal, Estela

“…Complement component 3 (C3) presents both slow (C3S) and fast (C3F) variants, which can be locally produced and activated by immune system cells. We studied C3…”
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Defending against SARS-CoV-2: The T cell perspective by Almendro-Vázquez, Patricia, Laguna-Goya, Rocío, Paz-Artal, Estela

“…SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-19 outcome and long-term memory. Impaired early T cell-driven immunity…”
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SARS-CoV-2-specific Cell-mediated Immunity in Kidney Transplant Recipients Recovered From COVID-19 by Fernández-Ruiz, Mario, Olea, Beatriz, Giménez, Estela, Laguna-Goya, Rocío, Trujillo, Hernando, Caravaca-Fontán, Fernando, Gutiérrez, Eduardo, López-Medrano, Francisco, Remigia, María José, Almendro-Vazquez, Patricia, Polanco, Natalia, González, Esther, Ruiz-Merlo, Tamara, Parra, Patricia, San Juan, Rafael, Andrés, Amado, Navarro, David, Aguado, José María

“…The magnitude and kinetics of severe acute respiratory syndrome coronavirus 2-specific cell-mediated immunity (SARS-CoV-2-CMI) in kidney transplant (KT)…”
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WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis by Kaiser, Karol, Gyllborg, Daniel, Procházka, Jan, Salašová, Alena, Kompaníková, Petra, Molina, Francisco Lamus, Laguna-Goya, Rocio, Radaszkiewicz, Tomasz, Harnoš, Jakub, Procházková, Michaela, Potěšil, David, Barker, Roger A., Casado, Ángel Gato, Zdráhal, Zbyněk, Sedláček, Radislav, Arenas, Ernest, Villaescusa, J. Carlos, Bryja, Vítězslav

“…WNTs are lipid-modified proteins that control multiple functions in development and disease via short- and long-range signaling. However, it is unclear how…”
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Longitudinal profile of circulating T follicular helper lymphocytes parallels anti‐HLA sensitization in renal transplant recipients by Cano‐Romero, Francisco Luis, Laguna Goya, Rocío, Utrero‐Rico, Alberto, Gómez‐Massa, Elena, Arroyo‐Sánchez, Daniel, Suárez‐Fernández, Patricia, Lora, David, Andrés, Amado, Castro‐Panete, Mª José, Paz‐Artal, Estela

“…Antibody‐mediated rejection is responsible for 30%‐50% of renal graft failures. Differentiation of B cells into antibody‐producing plasmablasts depends on the…”
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SARS-CoV-2-specific T-cell responses after COVID-19 recovery in patients with rheumatic diseases on immunosuppressive therapy by Lledó, Ana, Retuerto, Miriam, Almendro-Vázquez, Patricia, Fernández-Ruiz, Mario, Galindo, María, Laguna-Goya, Rocío, Paz-Artal, Estela, Lalueza, Antonio, Aguado, José M., Pablos, José L.

“…•Patients with rheumatic diseases show an adequate cellular immune response after SARS-COV-2 infection.•T-cell responses to SARS-COV-2 antigens were similar in…”
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A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease by Villaescusa, J Carlos, Li, Bingsi, Toledo, Enrique M, Rivetti di Val Cervo, Pia, Yang, Shanzheng, Stott, Simon RW, Kaiser, Karol, Islam, Saiful, Gyllborg, Daniel, Laguna-Goya, Rocio, Landreh, Michael, Lönnerberg, Peter, Falk, Anna, Bergman, Tomas, Barker, Roger A, Linnarsson, Sten, Selleri, Licia, Arenas, Ernest

“…Pre‐B‐cell leukemia homeobox (PBX) transcription factors are known to regulate organogenesis, but their molecular targets and function in midbrain dopaminergic…”
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Analysis of the factors predicting clinical response to tocilizumab therapy in patients with severe COVID-19 by San-Juan, Rafael, Fernández-Ruiz, Mario, López-Medrano, Francisco, Carretero, Octavio, Lalueza, Antonio, Maestro de la Calle, Guillermo, Pérez-Jacoiste Asín, María Asunción, Bueno, Héctor, Caro-Teller, José Manuel, Catalán, Mercedes, de la Calle, Cristina, García-García, Rocío, Gómez, Carlos, Laguna-Goya, Rocío, Lizasoáin, Manuel, Martínez-López, Joaquín, Origüen, Julia, Sevillano, Ángel, Gutiérrez, Eduardo, de Miguel, Borja, Aguilar, Fernando, Parra, Patricia, Ripoll, Mar, Ruiz-Merlo, Tamara, Trujillo, Hernando, Pablos, José Luis, Paz-Artal, Estela, Lumbreras, Carlos, Aguado, José María

“…•Improvement at 14 days occurs in 63.3% of severe COVID-19 treated with tocilizumab.•Early administration of tocilizumab is associated with better clinical…”
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Early renal graft function deterioration in recipients with preformed anti-MICA antibodies: partial contribution of complement-dependent cytotoxicity by Sánchez-Zapardiel, Elena, Castro-Panete, María José, Mancebo, Esther, Morales, Pablo, Laguna-Goya, Rocío, Morales, José María, Apaza, Jacqueline, de Andrés, Amado, Talayero, Paloma, Paz-Artal, Estela

“…We previously reported that preformed anti-MHC class I-related chain A (MICA) antibodies increase the risk for renal graft rejection and enhance the…”
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Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens by Ribeiro, Diogo, Laguna Goya, Rocio, Ravindran, Geeta, Vuono, Romina, Parish, Clare L, Foldi, Claire, Piroth, Tobias, Yang, Shanzheng, Parmar, Malin, Nikkhah, Guido, Hjerling-Leffler, Jens, Lindvall, Olle, Barker, Roger A, Arenas, Ernest

“…Abstract Human fetal midbrain tissue grafting has provided proof-of-concept for dopamine cell replacement therapy (CRT) in Parkinson's disease (PD). However,…”
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Longitudinal dynamics of SARS-CoV-2-specific cellular and humoral immunity after natural infection or BNT162b2 vaccination by Almendro-Vázquez, Patricia, Laguna-Goya, Rocio, Ruiz-Ruigomez, Maria, Utrero-Rico, Alberto, Lalueza, Antonio, Maestro de la Calle, Guillermo, Delgado, Pilar, Perez-Ordoño, Luis, Muro, Eva, Vila, Juan, Zamarron, Isabel, Moreno-Batanero, Miguel, Chivite-Lacaba, Marta, Gil-Etayo, Francisco Javier, Martín-Higuera, Carmen, Meléndez-Carmona, María Ángeles, Lumbreras, Carlos, Arellano, Irene, Alarcon, Balbino, Allende, Luis Miguel, Aguado, Jose Maria, Paz-Artal, Estela

“…The timing of the development of specific adaptive immunity after natural SARS-CoV-2 infection, and its relevance in clinical outcome, has not been…”
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