Search Results - "Laguna, C."
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Pemafibrate abrogates SLD in a rat experimental dietary model, inducing a shift in fecal bile acids and microbiota composition
Published in Biomedicine & pharmacotherapy (01-08-2024)“…Drugs resolving steatotic liver disease (SLD) could prevent the evolution of metabolic dysfunction associated SLD (MASLD) to more aggressive forms but must…”
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Bempedoic Acid Restores Liver H2S Production in a Female Sprague-Dawley Rat Dietary Model of Non-Alcoholic Fatty Liver
Published in International journal of molecular sciences (28-12-2022)“…We previously demonstrated that treatment with BemA (bempedoic acid), an inhibitor of ATP citrate lyase, significantly reduces fatty liver in a model of liver…”
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Way back for fructose and liver metabolism: Bench side to molecular insights
Published in World journal of gastroenterology : WJG (07-12-2012)“…The World Health Organization recommends that the daily intake of added sugars should make up no more than 10% of total energy. The consumption of sugar-…”
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Fructose supplementation impairs rat liver autophagy through mTORC activation without inducing endoplasmic reticulum stress
Published in Biochimica et biophysica acta (01-02-2015)“…Supplementation with 10% liquid fructose to female rats for 2weeks caused hepatic steatosis through increased lipogenesis and reduced peroxisome proliferator…”
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Liver AMP/ATP ratio and fructokinase expression are related to gender differences in AMPK activity and glucose intolerance in rats ingesting liquid fructose
Published in The Journal of nutritional biochemistry (01-08-2011)“…Women, but not men, show an association between fructose consumption and an increased risk of Type 2 diabetes mellitus. As rats are considered a model for…”
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Fructose during pregnancy affects maternal and fetal leptin signaling
Published in The Journal of nutritional biochemistry (01-10-2013)“…Fructose intake from added sugars correlates with the epidemic rise in obesity, metabolic syndrome and cardiovascular diseases. Fructose intake also causes…”
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Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells
Published in Biochimica et biophysica acta (01-04-2014)“…Fructose ingestion is associated with the production of hepatic steatosis and hypertriglyceridemia. For fructose to attain these effects in rats, simultaneous…”
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Liquid fructose in pregnancy exacerbates fructose-induced dyslipidemia in adult female offspring
Published in The Journal of nutritional biochemistry (01-06-2016)“…Fructose intake from added sugars correlates with the epidemic rise in metabolic syndrome and related events. Nevertheless, consumption of beverages sweetened…”
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Activation of Peroxisome Proliferator–Activated Receptor β/δ Inhibits Lipopolysaccharide-Induced Cytokine Production in Adipocytes by Lowering Nuclear Factor-κB Activity via Extracellular Signal–Related Kinase 1/2
Published in Diabetes (New York, N.Y.) (01-08-2008)“…Activation of Peroxisome Proliferator–Activated Receptor β/δ Inhibits Lipopolysaccharide-Induced Cytokine Production in Adipocytes by Lowering Nuclear…”
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Fructose during pregnancy provokes fetal oxidative stress: The key role of the placental heme oxygenase-1
Published in Molecular nutrition & food research (01-12-2016)“…Scope One of the features of metabolic syndrome caused by liquid fructose intake is an impairment of redox status. We have investigated whether maternal…”
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Effects of Maternal Fructose Intake on Perinatal ER-Stress: A Defective XBP1s Nuclear Translocation Affects the ER-stress Resolution
Published in Nutrients (17-08-2019)“…Endoplasmic reticulum (ER) homeostasis is crucial to appropriate cell functioning, and when disturbed, a safeguard system called unfolded protein response…”
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Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment
Published in Toxicology and applied pharmacology (15-02-2011)“…Consumption of beverages that contain fructose favors the increasing prevalence of metabolic syndrome alterations in humans, including non-alcoholic fatty…”
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Emphysematous pancreatitis: Clinical course and management
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-04-2022)Get full text
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Metabolic alterations and increased liver mTOR expression precede the development of autoimmune disease in a murine model of lupus erythematosus
Published in PloS one (04-12-2012)“…Although metabolic syndrome (MS) and systemic lupus erythematosus (SLE) are often associated, a common link has not been identified. Using the BWF1 mouse,…”
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Opposite fates of fructose in the development of metabolic syndrome
Published in World journal of gastroenterology : WJG (07-09-2012)“…This short review comments on the recently published work of Ishimoto et al regarding the opposing effects of fructokinase C and A isoforms on fructoseinduced…”
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A Wavelet-Based Correlation Analysis Framework to Study Cerebromuscular Activity in Essential Tremor
Published in Complexity (New York, N.Y.) (01-01-2018)“…Objective. Deep brain stimulation (DBS) provides dramatic tremor relief in patients with severe essential tremor (ET). Typically, the VIM nucleus is the most…”
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Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages
Published in Biochimica et biophysica acta (01-06-2011)“…Tissue factor pathway inhibitor 2 (TFPI2) is a serine protease inhibitor critical for the regulation of extracellular matrix remodeling and atherosclerotic…”
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Type II interleukin-1 receptor expression is reduced in monocytes/macrophages and atherosclerotic lesions
Published in Biochimica et biophysica acta (01-09-2011)“…Type II interleukin-1 receptor (IL-1R2) is a non-signaling decoy receptor that negatively regulates the activity of interleukin-1 (IL-1), a pro-inflammatory…”
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Multilayer Structure in SeAsGeSi-based OTS for High Thermal Stability and Reliability Enhancement
Published in ESSDERC 2022 - IEEE 52nd European Solid-State Device Research Conference (ESSDERC) (19-09-2022)“…In this paper, we present an innovative Multilayer SeAsGeSi-based Ovonic Threshold Switching (OTS) Selector targeting high reliability for Crossbar arrays. We…”
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