Search Results - "Lagasse, Alex"

Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators by Allensworth‐James, Melody L., Odle, Angela K., Lim, Juchan, LaGasse, Alex N., Miles, Tiffany K., Hardy, Linda L., Haney, Anessa C., MacNicol, Melanie C., MacNicol, Angus M., Childs, Gwen V.

“…In normal individuals, pituitary somatotrophs optimise body composition by responding to metabolic signals from leptin. To identify mechanisms behind the…”
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The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs by Banik, Jewel, Moreira, Ana Rita Silva, Lim, Juchan, Tomlinson, Sophia, Hardy, Linda L., Lagasse, Alex, Haney, Anessa, Crimmins, Meghan R., Boehm, Ulrich, Odle, Angela K., MacNicol, Melanie C., Childs, Gwen V., MacNicol, Angus M.

“…The pituitary functions as a master endocrine gland that secretes hormones critical for regulation of a wide variety of physiological processes including…”
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Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain by Miles, Tiffany K, Allensworth-James, Melody L, Odle, Angela K, Silva Moreira, Ana Rita, Haney, Anessa C, LaGasse, Alex N, Gies, Allen J, Byrum, Stephanie D, Riojas, Angelica M, MacNicol, Melanie C, MacNicol, Angus M, Childs, Gwen V

“…Maternal nutrition during embryonic development and lactation influences multiple aspects of offspring health. Using mice, this study investigates the effects…”
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Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism by Miles, Tiffany K, Odle, Angela K, Byrum, Stephanie D, Lagasse, Alex, Haney, Anessa, Ortega, Victoria G, Bolen, Cole R, Banik, Jewel, Reddick, Milla M, Herdman, Ashley, MacNicol, Melanie C, MacNicol, Angus M, Childs, Gwen V

“…Abstract Anterior pituitary cell function requires a high level of protein synthesis and secretion which depend heavily on mitochondrial adenosine triphosphate…”
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Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle by Moreira, Ana Rita Silva, Lim, Juchan, Urbaniak, Alicja, Banik, Jewel, Bronson, Katherine, Lagasse, Alex, Hardy, Linda, Haney, Anessa, Allensworth, Melody, Miles, Tiffany K, Gies, Allen, Byrum, Stephanie D, Wilczynska, Ania, Boehm, Ulrich, Kharas, Michael, Lengner, Christopher, MacNicol, Melanie C, Childs, Gwen V, MacNicol, Angus M, Odle, Angela K

“…Abstract The anterior pituitary controls key biological processes, including growth, metabolism, reproduction, and stress responses through distinct cell types…”
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Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi by Allensworth-James, Melody, Banik, Jewel, Odle, Angela, Hardy, Linda, Lagasse, Alex, Moreira, Ana Rita Silva, Bird, Jordan, Thomas, Christian L, Avaritt, Nathan, Kharas, Michael G, Lengner, Christopher J, Byrum, Stephanie D, MacNicol, Melanie C, Childs, Gwen V, MacNicol, Angus M

“…Abstract The adipokine leptin regulates energy homeostasis through ubiquitously expressed leptin receptors. Leptin has a number of major signaling targets in…”
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8649 Ablation of Leptin Receptors in Somatotropes Impacts Transcriptomic Plasticity in the Pou1f1 Lineage of Female Pituitary Cells by Miles, Tiffany K, Odle, Angela Katherine, Byrum, Stephanie, Lagasse, Alex, Haney, Anessa, Ortega, Victoria G, Herdman, Ashley, MacNicol, Melanie C, MacNicol, Angus M, Childs, Gwen V

“…Abstract Disclosure: T.K. Miles: None. A.K. Odle: None. S. Byrum: None. A. Lagasse: None. A. Haney: None. V.G. Ortega: None. A. Herdman: None. M.C. MacNicol:…”
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PMON55 Calcium Imaging in the Intact Mouse Pituitary: A Novel Design for Understanding the Formation and Modulation of the Gonadotrope Network by Herdman, Ashley, Lagasse, Alex, MacNicol, Kenzie, Haney, Anessa, Boehm, Uli, MacNicol, Melanie, MacNicol, Angus, Childs, Gwen, Hyde, James, Odle, Angela

“…Abstract The reproductive cells of the pituitary, the gonadotropes, develop after e12.75 in mice and continue to differentiate and migrate throughout puberty…”
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THU043 Single-cell Transcriptomics Show Sex-specific Responses To A High Fat Diet, Under Thermoneutral Conditions, Pointing To Reduced Pituitary Plasticity by Miles, Tiffany K, Lagasse, Alex N, Odle, Angela Katherine, Lira, Samia Sultana, Syed, Mohsin M, Akhter, Noor, MacNicol, Melanie C, MacNicol, Angus M, Childs, Gwen V

“…Abstract Disclosure: T.K. Miles: None. A.N. Lagasse: None. A.K. Odle: None. S.S. Lira: None. M.M. Syed: None. N. Akhter: None. M.C. MacNicol: None. A.M…”
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FRI290 Proteomic Identification Of Secretoneurin-Stimulated Proteins In Purified Mouse Gonadotropes by Herdman, Ashley, Lagasse, Alex, Haney, Anessa, Byrum, Stephanie, Miles, Tiffany, Boehm, Uli, MacNicol, Melanie C, MacNicol, Angus M, Childs, Gwen V, Odle, Angela K

“…Abstract Disclosure: A. Herdman: None. A. Lagasse: None. A. Haney: None. S. Byrum: None. U. Boehm: None. M.C. MacNicol: None. A.M. MacNicol: None. G.V. Childs:…”
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8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice by Miles, Tiffany K, Ortega, Victoria G, Carroll, Kya D, Odle, Angela Katherine, Byrum, Stephanie D, Gies, Allen J, Lagasse, Alex N, Haney, Anessa C, MacNicol, Melanie C, MacNicol, Angus M, Childs, Gwen V

“…Abstract Disclosure: T.K. Miles: None. V.G. Ortega: None. K.D. Carroll: None. A.K. Odle: None. S.D. Byrum: None. A.J. Gies: None. A.N. Lagasse: None. A.C…”
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Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi by Allensworth-James, Melody, Banik, Jewel, Odle, Angela, Hardy, Linda, Lagasse, Alex, Moreira, Ana Rita Silva, Bird, Jordan, Thomas, Christian L, Avaritt, Nathan, Kharas, Michael G, Lengner, Christopher J, Byrum, Stephanie D, MacNicol, Melanie C, Childs, Gwen V, MacNicol, Angus M

“…The adipokine leptin regulates energy homeostasis through ubiquitously expressed leptin receptors. Leptin has a number of major signaling targets in the brain,…”
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Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi by Allensworth-James, Melody, Banik, Jewel, Odle, Angela, Hardy, Linda, Lagasse, Alex, Moreira, Ana Rita Silva, Bird, Jordan, Thomas, Christian L, Avaritt, Nathan, Kharas, Michael G, Lengner, Christopher J, Byrum, Stephanie D, MacNicol, Melanie C, Childs, Gwen V, MacNicol, Angus M

“…The adipokine leptin regulates energy homeostasis through ubiquitously expressed leptin receptors. Leptin has a number of major signaling targets in the brain,…”
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SAT-284 Musashi Exerts Translational Control Within Anterior Pituitary Cells of the POU1F1 Lineage by Allensworth, Melody Lyn, Odle, Angela Katherine, Moreira, Ana Rita Silva, Lim, Juchan, Banik, Jewel, Haney, Anessa, Lagasse, Alex, Hardy, Linda, Byrum, Stephanie, Avaritt, Nathan, MacNicol, Melanie C, Childs, Gwen V, MacNicol, Angus M

“…Abstract The activation of transcription factor Pou1f1 at embryonic day 13 gives rise to the pituitary populations of somatotropes, lactotropes, and…”
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