Search Results - "Lafrasse, C. Rodriguez"

Cellular and molecular portrait of eleven human glioblastoma cell lines under photon and carbon ion irradiation by Ferrandon, S, Magné, N, Battiston-Montagne, P, Hau-Desbat, N.-H, Diaz, O, Beuve, M, Constanzo, J, Chargari, C, Poncet, D, Chautard, E, Ardail, D, Alphonse, G, Rodriguez-Lafrasse, C

“…Highlights • This study provides consistent database of the cellular and molecular response of glioblastoma cells to photon irradiation. • To the best of our…”
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Spectrum of pathogenic mutations and associated polymorphisms in a cohort of 44 unrelated patients with long QT syndrome by Millat, G, Chevalier, P, Restier-Miron, L, Da Costa, A, Bouvagnet, P, Kugener, B, Fayol, L, Gonzàlez Armengod, C, Oddou, B, Chanavat, V, Froidefond, E, Perraudin, R, Rousson, R, Rodriguez-Lafrasse, C

“…Long QT syndrome (LQTS) is a rare and clinically heterogeneous inherited disorder characterized by a long QT interval on the electrocardiogram, increased risk…”
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Use of nanoparticles as radiosensitizing agents in radiotherapy: State of play by Verry, C, Porcel, E, Chargari, C, Rodriguez-Lafrasse, C, Balosso, J

“…Nanomedicine has undergone significant development since the 2000s and it is only very recently that two metallic nanoparticles have emerged in clinical…”
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Gadolinium-Based Nanoparticles Can Overcome the Radioresistance of Head and Neck Squamous Cell Carcinoma Through the Induction of Autophagy by Simonet, S, Rodriguez-Lafrasse, C, Beal, D, Gerbaud, S, Malesys, C, Tillement, O, Lux, F, Fayyad-Kazan, H, Rachidi, W, Ardail, D

“…Radiation therapy is a mainstay in the therapeutic management of Head and Neck Squamous Cell Carcinoma (HNSCC). Despite significant progress in this field,…”
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Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers by Gibert, B, Hadchity, E, Czekalla, A, Aloy, M-T, Colas, P, Rodriguez-Lafrasse, C, Arrigo, A-P, Diaz-Latoud, C

“…Human heat shock protein 27 (Hsp27, HspB1) is an anti-apoptotic protein characterized for its tumorigenic and metastatic properties, and now referenced as a…”
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Proof of Concept of the Radiosensitizing Effect of Gadolinium Oxide Nanoparticles in Cell Spheroids and a Tumor-Implanted Murine Model of Chondrosarcoma by Aloy, Marie-Thérèse, Sidi Boumedine, Jacqueline, Deville, Agathe, Kryza, David, Gauthier, Arnaud, Brichart-Vernos, Delphine, Ollier, Grégoire, La Padula, Veronica, Lux, François, Tillement, Olivier, Rodriguez-Lafrasse, Claire, Janier, Marc

“…Chondrosarcomas (CHSs), which represent 20% of primary bone tumors in adults, are mostly resistant to radio- and chemotherapy. It is therefore essential that…”
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Comparison of OncoBEAM and NGS methods to detect plasma EGFR T790M mutations at progression of NSCLC by Garcia, J., Delherme, A., Geigeur, F., Merle, P., Tissot, C., Jones, F.S., Edelstein, D., Souquet, P.-J., Rodriguez-Lafrasse, C., Couraud, S., Payen, L.F., Xu, Z.

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Navigating the highlights of phase III trials: a watchful eye on evidence-based radiotherapy by Trone, J.C., Espenel, S., Rehailia-Blanchard, A., Guillaume, E., Vial, N., Rancoule, C., Rodriguez-Lafrasse, C., Ben Mrad, M., El Meddeb Hamrouni, A., Ollier, E., Chargari, C., Deutsch, E., Vallard, A., Magné, N.

“…Phase III randomized controlled trials (RCTs) are the cornerstone of evidence-based oncology. However, there is no exhaustive review describing the…”
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In vitro radiosensitizing effects of ultrasmall gadolinium based particles on tumour cells by Mowat, P, Mignot, A, Rima, W, Lux, F, Tillement, O, Roulin, C, Dutreix, M, Bechet, D, Huger, S, Humbert, L, Barberi-Heyob, M, Aloy, M T, Armandy, E, Rodriguez-Lafrasse, C, Le Duc, G, Roux, S, Perriat, P

“…Since radiotherapy is widely used in cancer treatment, it is essential to develop strategies which lower the irradiation burden while increasing efficacy and…”
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HER Family Blockade in Head and Neck Squamous Cell Carcinoma: Couple Therapy Efficacy of Cetuximab and Pertuzumab Combined With Photon Irradiation by Guy, J.B, Méry, B, Rancoule, C, Vallard, A, Espenel, S, Wozny, A.S, Simonet, S, Bernard, D, Ardail, D, Beuve, M, Alphonse, G, Rodriguez-Lafrasse, C, Magné, N

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HIF-1α plays a key role in the response of HNSCC cancer stem cells to photon and carbon ion exposures by Wozny, A.-S, Lauret, A, Saintigny, Y, Battiston-Montagne, P, Beuve, M, Alphonse, G, Rodriguez-Lafrasse, C

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High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer by Berthier, A, Seguin, S, Sasco, A J, Bobin, J Y, De Laroche, G, Datchary, J, Saez, S, Rodriguez-Lafrasse, C, Tolle, F, Fraichard, A, Boyer-Guittaut, M, Jouvenot, M, Delage-Mourroux, R, Descotes, F

“…Background: This study evaluates the relation of the early oestrogen-regulated gene gabarapl1 to cellular growth and its prognostic significance in breast…”
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50: Radiograaff: a medium energy proton irradiation platform for radiobiological studies. Presentation and first results by Dauvergne, D, Constanzo, J, Fallavier, M, Alphonse, G, Battiston-Montagne, P, Bernard, C, Rodriguez-Lafrasse, C, Beuve, M

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From the carbon track to therapeutic efficiency of hadrontherapy by Rodriguez-Lafrasse, C, Balosso, J

“…Carbon ions, thanks to their relative biological effectiveness much higher than that of photons and protons and their ballistic characteristics similar to…”
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Radiograaff, a proton irradiation facility for radiobiological studies at a 4MV Van de Graaff accelerator by Constanzo, J., Fallavier, M., Alphonse, G., Bernard, C., Battiston-Montagne, P., Rodriguez-Lafrasse, C., Dauvergne, D., Beuve, M.

“…A horizontal beam facility for radiobiological experiments with low-energy protons has been set up at the 4MV Van de Graaff accelerator of the Institut de…”
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168: Gadolinium based nanoparticles for radiosensitization of head and neck squamous cell carcinoma by Rodriguez-Lafrasse, C, Aloy, M.–T, Miladi, I, Armandy, E, Sancey, L, Berniard, A, Billotey, C, Tillement, O, Lux, F, Perriat, P, Janier, M

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Genetic heterogeneity in Niemann-Pick C disease : A study using somatic cell hybridization and linkage analysis by VANIER, M. T, DUTHEL, S, RODRIGUEZ-LAFRASSE, C, PENTCHEV, P, CASTEA, E. D

“…The primary molecular defect underlying Niemann-Pick C disease (NPC) is still unknown. A wide spectrum of clinical and biochemical phenotypes has previously…”
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Niemann‐Pick disease type C: An update by Vanier, M. T., Pentchev, P., Rodriguez‐Lafrasse, C., Rousson, R.

“…Summary The concept of Niemann‐Pick disease type C as a secondary sphingomyelin storage disorder (in contrast to the sphingomyelinase‐deficient types A and B)…”
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Temporal relationships between ceramide production, caspase activation and mitochondrial dysfunction in cell lines with varying sensitivity to anti-Fas-induced apoptosis by Rodriguez-Lafrasse, C, Alphonse, G, Broquet, P, Aloy, M T, Louisot, P, Rousson, R

“…To clarify the chronology of events leading to anti-Fas-induced apoptosis, and the mechanisms of resistance to this death effector, we compared the response…”
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Ceramide induces activation of the mitochondrial/caspases pathway in Jurkat and SCC61 cells sensitive to γ-radiation but activation of this sequence is defective in radioresistant SQ20B cells by Alphonse, G., Aloy, M.-T., Broquet, P., Gerard, J.-P., Louisot, P., Rousson, R., Rodriguez-Lafrasse, C.

“…Purpose : To clarify the molecular mechanisms leading to radiation-induced apoptosis or resistance, the kinetics (1-48 h) and sequence of events triggered in…”
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